Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial update for autologous CAR-T/TCR-T cell immunotherapy targeting multiple malignancies; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma [Phase 1]
Phase 1 biomarker study evaluating nivolumab with ipilimumab, and nivolumab in combination with ipilimumab, in advanced/metastatic melanoma;…
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CLINICAL_TRIALS trial_result · 2019-11-19Clinical Trial Update: Hu14.18-Interleukin-2 Fusion Protein in Treating Patients With Advanced Melanoma [Phase 2]
Phase 2 trial assessing Hu14.18-Interleukin-2 fusion protein in advanced melanoma has been completed.
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases [Phase 2]
Phase 2 trial evaluating metformin for preventing glucocorticoid-induced diabetes in patients with brain metastases, with melanoma context.
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CLINICAL_TRIALS trial_result · 2019-11-12Clinical Trial Update: RFT-5-dgA in Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial update for RFT-5-dgA in metastatic melanoma; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: Tumor-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy Following Cyclophosphamide And Fludarabine In Patients With Melanoma [Phase 2]
Phase 2 trial evaluating tumor-infiltrating lymphocytes with low-dose interleukin-2 after cyclophosphamide and fludarabine in metastatic mel…
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CLINICAL_TRIALS trial_result · 2019-10-22Clinical Trial Update: Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma [Phase 2]
Phase 2 pilot trial of hu14.18-IL2 in resectable recurrent stage III or stage IV melanoma has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-16Clinical Trial Update: Melanoma Vaccine With Peptides and Leuprolide [Phase 2]
Phase 2 trial update of a melanoma vaccine combining peptides with leuprolide has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: Neoadjuvant Trial of Nivolumab in Combination With HF10 Oncolytic Viral Therapy in Resectable Stage IIIB, IIIC, IVM1a Melanoma [Phase 2]
Phase 2 neoadjuvant trial evaluating nivolumab with HF10 oncolytic viral therapy in resectable advanced melanoma was terminated; results pos…
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CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: Evaluation of a New Anti-cancer Immunotherapy in Patients With Non-operable and Progressing Metastatic Cutaneous Melanoma [Phase 1]
Phase 1 trial update evaluating a new anti-cancer immunotherapy in non-operable, progressing metastatic cutaneous melanoma.
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CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors [Phase 1, Phase 2]
A phase 1/2 study evaluating PLX3397 in combination with pembrolizumab in advanced melanoma and other solid tumors was terminated; results w…
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Improving Goals of Care Discussion in Advanced Cancer Patients [NA]
Clinical trial update reporting completion and results posting for a study focused on improving goals of care discussions in advanced cancer…
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CLINICAL_TRIALS trial_result · 2019-09-27Clinical Trial Update: Study of GSK2132231A Antigen-Specific Cancer Immunotherapeutic in Patients With Inoperable Metastatic Cutaneous Melanoma [Phase 2]
Phase 2 trial update for an antigen-specific cancer immunotherapeutic in patients with inoperable metastatic cutaneous melanoma has complete…
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CLINICAL_TRIALS trial_result · 2019-09-26Clinical Trial Update: Trial of pIL-12 Electroporation Malignant Melanoma [Phase 2]
Phase 2 clinical trial update for pIL-12 electroporation in malignant melanoma completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-20Clinical Trial Update: Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography Texture Analysis as a Predictive Biomarker [Phase 2]
Phase 2 trial investigating pembrolizumab in metastatic melanoma with CT texture analysis as a predictive biomarker; study terminated with p…
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: A Phase I Clinical Study With Investigational Compound LTT462 in Adult Patients With Specific Advanced Cancers. [Phase 1]
Phase I trial update for investigational compound LTT462 in adults with advanced cancers; trial terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: High-activity Natural Killer Immunotherapy for Small Metastases of Melanoma [Phase 1, Phase 2]
Clinical trial updates in high-activity natural killer immunotherapy for small metastases of melanoma (Phase 1/Phase 2) has completed.
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced Melanoma [Phase 2]
Phase 2 study of Glembatumumab Vedotin as monotherapy or with immunotherapies in advanced melanoma was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: A Study to Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma [Phase 2]
Phase 2 trial evaluating detection of BRAF V600 mutation in cfDNA from plasma in participants with metastatic melanoma; completed.
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Trial of pIL-12/MK-3475 in Metastatic Melanoma [Phase 2]
Phase 2 trial of pIL-12/MK-3475 in metastatic melanoma completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma [Phase 1]
This Phase I study evaluates the safety and dosing of ipilimumab given with whole-brain radiation therapy or radiosurgery in patients with r…
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CLINICAL_TRIALS trial_result · 2019-08-08Clinical Trial Update: Trametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 Mutations [Phase 2]
Phase 2 trial update evaluating trametinib in advanced melanoma with BRAF non-V600 mutations; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-08-06Clinical Trial Update: Dendritic Cell Vaccines + Dasatinib for Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating dendritic cell vaccines in combination with dasatinib for metastatic melanoma has completed with results p…
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: SCH 54031 PEG12000 Interferon Alfa-2b (PEG Intron, MK-4031) vs. INTRON®A (SCH 30500, MK-2958) as Adjuvant Therapy for Melanoma (C98-135, MK-4031-002) [Phase 2, Phase 3]
A phase 2/3 trial comparing SCH 54031 PEG12000 interferon alfa-2b (PEG Intron) to INTRON A as adjuvant therapy for melanoma was terminated w…
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Ipilimumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma [Phase 2]
Phase 2 clinical trial evaluating the combination of ipilimumab and all-trans retinoic acid in advanced melanoma has completed with results …