Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma [Phase 2]
Phase 2 trial investigating the effects of vemurafenib on the immune system in advanced melanoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Safety and Efficacy of Recombinant Humanized Anti-PD-1 mAb for Patients With Locally Advanced or Metastatic Melanoma [Phase 2]
Phase 2 clinical trial update evaluating safety and efficacy of a recombinant humanized anti-PD-1 monoclonal antibody in locally advanced or…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: International Trial of the Efficacy and Safety of BCD-100 in Patients With Melanoma [Phase 2]
Phase 2 clinical trial update for BCD-100 in patients with melanoma.
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Survivorship Promotion In Reducing IGF-1 Trial [Phase 2]
Phase 2 trial evaluating survivorship promotion by reducing IGF-1 has completed, with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations [Phase 2]
Phase II open-label trial evaluating dabrafenib plus trametinib in unresectable stage III/IV BRAF-mutant melanoma; study completed with post…
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Doxycycline, Temozolomide and Ipilimumab in Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating doxycycline with temozolomide and ipilimumab in melanoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Safety and Efficacy of Sonocloud Device Combined With Nivolumab in Brain Metastases From Patients With Melanoma [Phase 1, Phase 2]
Clinical trial update on safety and efficacy of the Sonocloud device combined with nivolumab for brain metastases from melanoma, spanning Ph…
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CLINICAL_TRIALS trial_result · 2020-08-10Clinical Trial Update: Study of MLN2480 in Participants With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion in Participants With Metastatic Melanoma [Phase 1]
Phase 1 study of MLN2480 in relapsed/refractory solid tumors with dose expansion in metastatic melanoma has completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating a vaccine therapy for stage IV or recurrent malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161) [Phase 2]
Phase 2 trial investigating immunologic determinants of response to pembrolizumab (MK-3475) in advanced melanoma; study terminated with post…
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CLINICAL_TRIALS trial_result · 2020-06-18Clinical Trial Update: Immunotherapy of Stage III/IV Melanoma Patients [Phase 1]
Phase 1 immunotherapy trial in stage III/IV melanoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma [Phase 3]
Phase 3 trial comparing cobimetinib plus atezolizumab versus pembrolizumab in previously untreated advanced BRAFV600 wild-type melanoma; stu…
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma [Phase 1, Phase 2]
A clinical trial investigating an IDO inhibitor in combination with checkpoint inhibitors for metastatic melanoma has completed Phase 1/2 st…
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy [Phase 2]
Phase 2 trial evaluating induction therapy with vemurafenib and cobimetinib to optimize subsequent nivolumab and ipilimumab therapy in melan…
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CLINICAL_TRIALS trial_result · 2020-05-28Clinical Trial Update: Efficacy and Safety of Talimogene Laherparepvec Neoadjuvant Treatment Plus Surgery Versus Surgery Alone for Melanoma [Phase 2]
Phase 2 trial updating efficacy and safety of talimogene laherparepvec plus neoadjuvant surgery versus surgery alone for completely resectab…
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Adjuvant Dabrafenib (GSK2118436) in Patients With Surgically Resected AJCC Stage IIIC Melanoma Characterized by a BRAFV600E/K Mutation [Phase 2]
Phase 2 trial evaluating adjuvant dabrafenib (BRAFV600E/K) in surgically resected AJCC Stage IIIC melanoma with BRAFV600E/K mutation has com…
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CLINICAL_TRIALS trial_result · 2020-05-21Clinical Trial Update: Camrelizumab Plus Apatinib and Temozolomide as First Line Therapy in Advanced Acral Melanoma [Phase 2]
Phase 2 trial update evaluating camrelizumab plus apatinib and temozolomide as first-line therapy for advanced acral melanoma.
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CLINICAL_TRIALS trial_result · 2020-05-20Clinical Trial Update: Study of CDX-3379, a Human Monoclonal Antibody Targeting ERBB3, in Combination With the MEK Inhibitor, Trametinib, in Patients With Advanced Stage NRAS Mutant and BRAF/NRAS Wildtype (WT) Melanoma [Phase 1, Phase 2]
Phase 1/2 trial of CDX-3379 with trametinib in advanced NRAS-mutant or WT melanoma was terminated; no results posted in the snippet.
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: A Comparative Study in Chinese Subjects With Chemotherapy Naïve Stage IV Melanoma Receiving Ipilimumab (3 mg/kg) vs. Dacarbazine [Phase 3]
Phase 3 trial comparing ipilimumab (3 mg/kg) to dacarbazine in chemotherapy-naïve stage IV melanoma in Chinese subjects; results posted.
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CLINICAL_TRIALS trial_result · 2020-04-29Clinical Trial Update: Immunotherapy Study for Patients With Stage IV Melanoma [Phase 2]
Phase 2 clinical trial update for an immunotherapy study in stage IV/metastatic melanoma; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer [Phase 1, Phase 2]
Phase 1/2 trial of an individualized mRNA cancer vaccine targeting neoantigens in autologous tumors; study terminated with results posted in…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Flavopiridol in Treating Patients With Metastatic Malignant Melanoma [Phase 2]
Phase 2 trial investigating flavopiridol for metastatic malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: A Study of PLX3397 in Patients With Unresectable or Metastatic KIT-mutated Melanoma [NA]
The clinical trial evaluating PLX3397 (pexidartinib) in patients with unresectable or metastatic KIT-mutated melanoma has completed, with re…
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Immunotherapy of HLA-A2 Positive Stage II-IV Melanoma Patients [Phase 1, Phase 2]
Phase 1/2 trial update on immunotherapy for HLA-A2 positive stage II-IV melanoma; trial terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Study of Combination of Ipilimumab and Nivolumab in Patients With Melanoma [Phase 2]
This Phase 2 study evaluated the combination of ipilimumab and nivolumab in patients with melanoma. The trial has completed and results were…