Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-04-05Clinical Trial Update: Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy [Phase 2]
Phase 2 clinical trial update evaluating regorafenib for second-line treatment of C-kit mutated malignant melanoma.
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CLINICAL_TRIALS trial_result · 2021-04-01Clinical Trial Update: Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Investigational Treatments in Combination With Standard of Care Immune Checkpoint Inhibitors in Participants With Advanced Melanoma [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacodynamics of investigational treatments in combination with standard of care immun…
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: MK-3475 in Melanoma and NSCLC Patients With Brain Metastases [Phase 2]
Phase 2 trial update for MK-3475 (pembrolizumab) in melanoma and non-small cell lung cancer patients with brain metastases has completed wit…
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer [Phase 2]
Phase 2 trial update on T cell receptor immunotherapy targeting NY-ESO-1 in NY-ESO-1 expressing cancers; study is completed with results pos…
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Study to Investigate the Objective Response Rate of Dabrafenib in Combination With Trametinib in Subjects With BRAF V600 Mutation-Positive Melanoma [Phase 2]
Phase 2 trial update evaluating dabrafenib plus trametinib for BRAF V600 mutation-positive melanoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-03-11Clinical Trial Update: Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer [Phase 2]
Phase II trial of the CDK inhibitor PD 0332991 (palbociclib) in various adult solid tumors including colon and breast cancers has completed …
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CLINICAL_TRIALS trial_result · 2021-03-11Clinical Trial Update: Safety of TKI258 in Advanced/Metastatic Melanoma Subjects [Phase 1, Phase 2]
Clinical trial update reporting safety data for TKI258 in advanced/metastatic melanoma across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression [Phase 2]
Phase 2 trial update evaluating nivolumab plus relatlimab or nivolumab plus ipilimumab in metastatic melanoma stratified by MHC-II expressio…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Ipilimumab vs Ipilimumab Plus Nivolumab in Patients With Stage III-IV Melanoma Who Have Progressed or Relapsed on PD-1 Inhibitor Therapy [Phase 2]
Phase 2 trial comparing ipilimumab alone versus ipilimumab plus nivolumab in melanoma patients who progressed on PD-1 inhibitors; results co…
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: Ipilimumab With Carboplatin and Paclitaxel in Patients With Unresectable Stage III and Stage IV Melanoma [Phase 2]
Phase 2 trial evaluating ipilimumab with carboplatin and paclitaxel in patients with untreated unresectable stage III or stage IV melanoma.
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CLINICAL_TRIALS trial_result · 2021-02-01Clinical Trial Update: HD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic Melanoma [Phase 4]
Phase 4 trial update of HD IL-2 plus vemurafenib in patients with BRAF mutation-positive metastatic melanoma; study terminated.
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Trial of PI-88 With Dacarbazine in Patients With Metastatic Melanoma [Phase 2]
Phase II trial of PI-88 in combination with dacarbazine for metastatic melanoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant Melanoma [Phase 2]
A Phase 2 clinical trial evaluating axitinib, an anti-angiogenesis agent, in patients with stage III malignant melanoma has completed with p…
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma [Phase 2]
Phase II study of MEK162 as a single agent in patients with BRAF or NRAS mutant metastatic melanoma has completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Stage IV Melanoma [Phase 2]
Phase 2 trial of antineoplaston therapy in patients with Stage IV melanoma has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: A Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic Melanoma [Phase 1, Phase 2]
Clinical trial update for RAF265 in locally advanced or metastatic melanoma across Phase 1 and Phase 2; study completed.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol® [Phase 2]
Phase 2 trial updating autologous therapeutic vaccination against solid cancers using intratumoral Hiltonol shows completed status.
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma [Phase 2]
Phase 2 trial update comparing continuous vs intermittent dabrafenib plus trametinib in BRAFV600-mutant unresectable/metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2020-11-23Clinical Trial Update: Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT) [Phase 2]
Phase 2 trial exploring pembrolizumab effects on natural killer cell exhaustion in melanoma was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-11-19Clinical Trial Update: A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma [Phase 3]
A Phase 3 trial evaluated atezolizumab plus cobimetinib and vemurafenib versus placebo plus cobimetinib and vemurafenib in previously untrea…
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CLINICAL_TRIALS trial_result · 2020-11-13Clinical Trial Update: Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma [Phase 3]
Phase 3 trial comparing fotemustine and dacarbazine to dacarbazine with or without alpha interferon in advanced malignant melanoma has compl…
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit [Phase 3]
A Phase 3 trial evaluating masitinib in metastatic melanoma with a c-KIT juxtamembrane domain mutation was terminated.
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Vaccination Plus Ontak in Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial update for vaccination plus Ontak in metastatic melanoma has been terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-10-26Clinical Trial Update: Ticilimumab (CP-675,206) in Treating Patients With Stage IIIC or Stage IV Melanoma [Phase 2]
Phase 2 trial update for ticilimumab (CP-675,206) in stage IIIC or stage IV melanoma; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer [Phase 1, Phase 2]
Phase 1/2 trial update of uprosertib combined with dabrafenib and trametinib in patients with stage IIIC-IV melanoma (cutaneous/metastatic/u…