Melanoma
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Cryoablation+Ipilimumab+Nivolumab in Melanoma [Phase 2]
A Phase 2 clinical trial at Massachusetts General Hospital is evaluating the combination of cryoablation with ipilimumab and nivolumab for m…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: CARE-Melanoma Trial [Phase 1]
Clinical trial update for CARE-Melanoma, a Phase 1 study in melanoma that is currently NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating PET-guided stereotactic body radiation therapy for oligoprogressive disease in non-small cell lung ca…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma [Phase 2]
A Phase 2 clinical trial is evaluating the combination of the IL-6 receptor inhibitor sarilumab with ipilimumab, nivolumab, and relatlimab f…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Study of Alterations in Tumor Metabolism Associated With the Development of Immunotherapy Resistance in Melanoma [NA]
Clinical trial update on a study examining alterations in tumor metabolism associated with immunotherapy resistance in melanoma; currently r…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study [NA]
This clinical trial update describes a microdosing PET imaging study using a 124I-labeled cRGDY silica nanomolecular particle tracer in pati…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma
A clinical trial update describing validation of molecular diagnostic assays that detect cancer biomarkers in blood and primary tumors. The …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
A clinical trial evaluating anti-PD-1 therapy by monitoring T cell responses in melanoma, lung cancer, and other cancers; currently recruiti…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Predictive Factors of Complete Response to Immunotherapy in Metastatic Melanoma: a Single-center Retrospective Study Between 2013 and 2021
A single-center retrospective study from University Hospital Strasbourg (2013–2021) examines factors that predict complete response to immun…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS) [NA]
This clinical trial update describes a telemedicine and mobile health symptom management intervention for advanced cancer patients (FOCUS), …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors [Phase 1]
A Phase 1 study evaluating KIN-2787 in participants with BRAF and/or NRAS mutation-positive solid tumors. The study includes patients with n…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating infliximab or vedolizumab to treat immune checkpoint inhibitor-related colitis in patients with genito…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Study of GC101 TIL in Advanced Melanoma [Phase 2]
A Phase 2 clinical trial evaluating GC101 TIL in advanced melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study) [Phase 2]
An update on a Phase 2 study evaluating SCIB1 and iSCIB1+ in melanoma patients treated with checkpoint inhibitors (nivolumab+ipilimumab or p…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Investigation of the ROle of faT and inflAmmaTory Cells in mElanoma
This entry describes a clinical trial investigating the role of fat and inflammatory cells in melanoma; recruitment has not yet begun.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: An Expanded Access Program for VO (RP1) in Combination With Nivolumab in Patients With Advanced Melanoma
This update notes that the Expanded Access Program for VO (RP1) in combination with nivolumab for advanced melanoma is no longer available.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of INBRX-106 in combination with pembrolizumab for locally advanced or metastatic sol…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers
A clinical trial update announcing a liquid biomarker study in melanoma and non-melanoma skin cancers that is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Neoadjuvant Dabrafenib + Trametinib for AJCC Stage IIIB-C BRAF V600 Mutation Positive Melanoma [Phase 2]
This document provides an update on a Phase 2 neoadjuvant trial of dabrafenib plus trametinib for AJCC Stage IIIB-C BRAF V600 mutation-posit…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body [Phase 1, Phase 2]
First-in-human Phase 1/2 trial evaluating REGN10597 alone or with cemiplimab in adults with melanoma, clear-cell renal cell carcinoma, and o…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Study of the Selective PI3K-Beta Inhibitor GSK2636771 in Combination With Pembrolizumab in Patients With Metastatic Melanoma and PTEN Loss [Phase 1, Phase 2]
Status update on a Phase 1/2 study of the selective PI3K-β inhibitor GSK2636771 in combination with pembrolizumab for metastatic melanoma wi…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Prospective Collection of Clinical Data and Human Body Material (HBM) of Cutaneous Melanoma and Non Melanoma Patients. Biobank Huidkanker
Prospective collection of clinical data and human body material from patients with cutaneous melanoma and non-melanoma skin cancer for bioba…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Reflectance Confocal Microscopy and Molecular Correlation in Atypical Melanocytic Lesions
Clinical trial evaluating reflectance confocal microscopy with molecular correlation and sequencing data to study atypical melanocytic lesio…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial evaluating immunotherapy or targeted therapy with or without stereotactic radiosurgery for brain metastases in patien…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study of GC101 TIL in Advanced Melanoma (10hospital) [EARLY_Phase 1]
An early-phase study evaluating GC101 Tumor Infiltrating Lymphocytes (TIL) for advanced melanoma is listed as recruiting, sponsored by Shang…