Melanoma
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma [Phase 2]
Phase II trial evaluating a combination of anti-PD-1 therapy and aldesleukin (IL-2) for metastatic melanoma and metastatic renal cell carcin…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Storage Facility for Tissues Obtained From Patients With Malignant Melanoma
Ongoing recruitment for a study at Ohio State University Comprehensive Cancer Center that involves collecting and storing tissue samples fro…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma [Phase 1]
A phase 1 trial investigating Nilotinib in combination with either Dabrafenib/Trametinib or Encorafenib/Binimetinib in metastatic melanoma w…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study [Phase 2]
A Phase 2 trial (The Knight SHIFT Study) is comparing morning versus afternoon administration of immunotherapy for advanced or metastatic so…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: HS-IT101 Injection Versus Chemotherapy in the Treatment of Advanced Melanoma [Phase 2]
A Phase 2 clinical trial update comparing HS-IT101 injection to chemotherapy for advanced melanoma (excluding uveal melanoma) is not yet rec…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App
This clinical trial is evaluating digital remote monitoring of immune checkpoint inhibitor–related toxicity using the Vigilant App. The stud…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population
This clinical trial update analyzes clinical outcomes and genomic data from American Indian patients across several cancer indications, with…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma [Phase 2]
This clinical trial update describes a Phase 2 study evaluating whether combination therapy with Fianlimab and Cemiplimab is safer and more …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1-2 study of ST101 in patients with advanced solid tumors, including glioblastoma and melanoma. The trial is currently active but not …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Personalized Circulating DNA Follow-up in Melanoma (PERCIMEL) [NA]
The PERCIMEL clinical trial investigates personalized circulating DNA follow-up in melanoma and is listed as active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED [Phase 2]
A Phase 2 neoadjuvant trial in melanoma evaluating immune checkpoint blockade in combination with a prebiotic dietary intervention (NEO-PreF…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating adaptive BRAF-MEK inhibitor therapy for advanced BRAF-mutant melanoma. The study is currently …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Study of MGC026 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update for MGC026 in participants with advanced solid tumors; study is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
This update describes the Moonshot Study's genetic analysis of blood and tissue samples from patients with advanced cancer; the study status…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma [Phase 1]
This Phase 1 study evaluates LN-144 or LN-145 in people with advanced uveal melanoma, undifferentiated pleomorphic sarcoma, dedifferentiated…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) [Phase 2]
Phase 2 clinical trial named ABC-X Study is evaluating an anti-PD-1 therapy in melanoma with radiotherapy extension, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients [NA]
A Mayo Clinic-led clinical trial is recruiting to assess whether incorporating mental health support and cognitive behavioral therapy for ca…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Diet and Immune Effects Trial: DIET- A Randomized Double Blinded Dietary Intervention Study in Patients With Metastatic Melanoma Receiving Immunotherapy [Phase 2]
A Phase 2 randomized, double-blind dietary intervention study in patients with melanoma receiving immunotherapy, evaluating whether dietary …
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Impact of a Prebiotic Food-enriched Diet (PreFED) in Combination With Ipilimumab/Nivolumab Combination Immune Checkpoint Blockade (ICB) in ICB-refractory Melanoma Patients [Phase 2]
Phase 2 study evaluating a PreFED diet in combination with ipilimumab and nivolumab for patients with ICB-refractory melanoma. The trial is …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating TGI-5 as a monotherapy and in combination with nivolumab in locally advanced or metastatic solid tumors; recruiting…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma [Phase 2]
Phase 2 neoadjuvant trial evaluating ipilimumab combined with nivolumab for recurrent, high-risk resectable melanoma; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Predicting Response to Anti-PD-1/PD-L1 Immunotherapy by Plasma Extracellular Vesicle Analysis
A clinical trial evaluating whether plasma extracellular vesicle analysis can predict response to anti-PD-1/PD-L1 immunotherapy in non-small…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS) [Phase 2]
Phase 2 clinical trial evaluating optimization of immunotherapy for advanced melanoma in the Brazilian public health system; the study is cu…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis [Phase 2]
Phase 2 clinical trial update on infliximab for immune checkpoint inhibitor–induced colitis; the study in melanoma patients is currently act…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors [NA]
A clinical trial update for proton pencil beam scanning GRID therapy aimed at bulky tumors, with ongoing activity but not recruiting, invest…