Melanoma
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial [NA]
The ICEMAN trial is evaluating narrow excision versus wide excision for adults with invasive cutaneous melanoma at clinical stages IA–IB to …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update for MC1R-targeted alpha-particle monotherapy, with a nivolumab combination, in adults with advance…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: IL-17 Blockade to Decrease irAEs (REPLAY) [Phase 1]
A Phase 1 clinical trial (REPLAY) is evaluating an IL-17 blockade approach to reduce immune-related adverse events in patients with metastat…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma [NA]
This clinical trial update compares imaging characteristics of the uEXPLORER PET/CT scanner with conventional PET/CT in patients with lung c…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma [Phase 1]
Phase 1 trial evaluating an intralesional influenza vaccine for treating stage I-IV cutaneous melanoma; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma
This clinical trial update describes an NCI study to characterize individuals and families at high risk of melanoma, including clinical, lab…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase II Clinical Trial on Neo-adjuvant Pembrolizumab in Patients With pT3b-T4a/b cN0M0 Melanoma. [Phase 2]
Phase II study assessing neoadjuvant pembrolizumab in patients with pT3b-T4a/b cN0M0 melanoma; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating a triple combination of tocilizumab, ipilimumab, and nivolumab for advanced melanoma, non-small cel…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma
Mayo Clinic is conducting a study to collect blood and tissue samples from family members of patients with pancreatic diseases, pancreatic c…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Characterisation of T Lymphocytes, NK Cells and Macrophages in Melanoma Patients
A completed clinical trial characterizing T lymphocytes, NK cells, and macrophages in melanoma patients to understand immune cell profiles i…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 With Lymphocyte-depleting Chemotherapy and TILs in the Treatment of Melanoma [Phase 1]
A Phase 1 clinical trial evaluating TILT-123, an oncolytic adenovirus encoding TNFα and IL-2, in combination with lymphocyte-depleting chemo…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: PD-L1 Targeting Peptide Probe for PET Imaging of Solid Tumor
A clinical trial update describes a PD-L1–targeting peptide probe for PET imaging of solid tumors, with not-yet-recruiting status and condit…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma [NA]
A trial is investigating consolidative radiotherapy to block oligoprogression in metastatic melanoma and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Belvarafenib in Combination With Cobimetinib in Patients With Locally Advanced or Metastatic NRAS-Mutant Melanoma [Phase 2]
A Phase 2 trial is evaluating belvarafenib in combination with cobimetinib for NRAS-mutant locally advanced or metastatic melanoma and is cu…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder [Phase 2]
Phase 2 clinical trial evaluating psilocybin-assisted psychotherapy for adjustment disorder in cancer patients; recruitment is ongoing acros…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases [Phase 1]
This document reports a Phase 1 trial update for an oncolytic adenovirus therapy targeting melanoma with intracranial and extracranial metas…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
This ClinicalTrials.gov entry notes molecular testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program and indicates on…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: RWS of Tunlametinib in NRAS-Mutant Advanced Melanoma [Phase 4]
Clinical trial update showing Phase 4 study of tunlametinib in NRAS-mutant advanced melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Investigating Real-Time Immunotherapy Symptoms Study [NA]
University of Pittsburgh is sponsoring a clinical trial to study real-time immunotherapy symptom monitoring, currently not yet recruiting, f…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Phase II Trial of LM103 in Advanced Melanoma [Phase 2]
Phase II clinical trial of LM103 for melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma [EARLY_Phase 1]
An early-phase clinical trial update evaluating adjuvant therapy guided by pathologic response after neoadjuvant treatment with encorafenib …
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: IDOV-Immune for Advanced Solid Tumors [Phase 1]
This report summarizes a Phase 1 trial of IDOV-Immune from ViroMissile, Inc. for advanced solid tumors, which is currently recruiting across…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update for HMBD-501 evaluating safety, tolerability, pharmacokinetics, and preliminary efficacy in HER3-e…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Immune Related Toxicity and Symptom Burden in Chronic Cancer Survivors With Melanoma Receiving Adjuvant Immunotherapy With Immune Checkpoint Inhibitors
This clinical trial update describes immune-related toxicity and symptom burden in chronic melanoma survivors receiving adjuvant immune chec…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Influence of a High-fiber Diet on the Microbiota and the Response to Immunotherapy in Patients Treated for Melanoma.
This clinical trial investigates whether a high-fiber diet modulates gut microbiota to improve the effectiveness of immunotherapy in melanom…