Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-mutant Advanced Melanoma. [Phase 1]
A Phase 1 clinical trial evaluating belvarafenib as a single agent and in combination with cobimetinib or cobimetinib plus nivolumab in NRAS…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Neoadjuvant Pucotenlimab Combined With Lenvatinib and Temozolomide in Resectable Stage IIB/III Acral Melanoma [Phase 2]
A Phase 2 neoadjuvant trial is evaluating pucotenlimab with lenvatinib and temozolomide for resectable acral melanoma (Stage IIB/III); the s…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue [NA]
A Memorial Sloan Kettering Cancer Center trial evaluating radiation therapy for solid tumors that have metastasized to soft tissue. The stud…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Evaluation of Skin Tests in Biotherapy Allergies [NA]
A University Hospital, Angers-sponsored trial evaluating skin tests in biotherapy allergies is NOT_YET_RECRUITING. The study lists Locally A…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Safety and Efficacy of OBX-115 in Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update indicates OBX-115 is being studied in advanced solid tumors in Phase 1 and Phase 2, with recruitment ongoing for ind…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors [Phase 1, Phase 2]
Georgiamune Inc. is conducting a Phase 1/2 safety and tolerability trial of GIM-531 in patients with advanced solid tumors, including stage …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanoma [Phase 2]
A Phase 2 clinical trial evaluating LND101 in fecal microbiota transplantation combined with immune checkpoint blockade for advanced melanom…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma [Phase 1]
A Phase 1 study from Dana-Farber Cancer Institute evaluating NeoVax plus CDX-301 with nivolumab or pembrolizumab in melanoma; the trial is c…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis [Phase 1, Phase 2]
This document outlines an ongoing Phase 1/2 clinical trial evaluating Hepzato Kit in combination with Opdualag for metastatic melanoma with …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma [Phase 2]
A Phase 2 clinical trial (NCT06466434) investigating a prebiotic food-enriched diet to enhance the microbiome and improve response to first-…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial [Phase 2]
A Phase 2 clinical trial update on the PET-Stop trial uses biomarkers to guide safe discontinuation of immunotherapy in patients with unrese…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV [Phase 1]
This is a Phase 1 clinical trial evaluating the combination of cabozantinib (XL184) and nivolumab in patients with various advanced cancers …
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial in metastatic melanoma evaluates lymphodepletion followed by adoptive cell transfer, with or without dendritic cell…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors. [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of BGB-A445 with tislelizumab in patients with select advanced solid tumors, includ…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases [Phase 2]
Phase 2 trial evaluating stereotactic brain-directed radiation with or without Aguix gadolinium-based nanoparticles for brain metastases; th…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors [Phase 1, Phase 2]
Roche is conducting a dose-escalation Phase 1/2 trial of a PD-1/LAG-3 bispecific antibody in patients with advanced or metastatic solid tumo…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A clinical trial is evaluating benefits and harms of cannabis/cannabinoid use among cancer patients treated in community oncology clinics; r…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma [Phase 1]
A Phase 1-1b clinical trial is evaluating the safety, preliminary efficacy, and dosimetry of study drug A9-3408 in patients with metastatic …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051) [Phase 1, Phase 2]
A pediatric Phase 1/2 study of pembrolizumab (Keytruda) in children with advanced solid tumors or lymphoma is currently recruiting. The tria…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Randomized, Double-Blind, Pharmacokinetic Similarity Study to Compare AVT32-DRL_PB With Keytruda® in Participants With Fully Resected Melanoma [Phase 1]
Phase 1 pharmacokinetic similarity study comparing AVT32-DRL_PB with Keytruda in participants with fully resected melanoma; not yet recruiti…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3] [Phase 3]
This Phase 3 trial IGNYTE-3 compares a VO oncolytic therapy plus nivolumab against physician's choice in advanced melanoma that progressed a…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study of Biological, Genetic, and Constitutional Factors and Non-invasive Monitoring to Assess Personal Cancer Risks
This clinical trial investigates how biological, genetic, and constitutional factors, plus non-invasive monitoring, can help assess individu…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of AMXT 1501 and DFMO with standard therapies in patients with advanced solid tumors, …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
A Mayo Clinic-sponsored phase 1/2 trial evaluating a personalized neoantigen peptide-based vaccine in combination with pembrolizumab for adv…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial update from Novartis assessing LXH254 combinations for efficacy and safety in patients with previously treated unre…