Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer [Phase 1]
Phase 1 trial update on MK-2206 plus hydroxychloroquine for advanced solid tumors, including melanoma, prostate cancer, and renal cell carci…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of TRK-950 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This ClinicalTrials.gov entry reports an ongoing Phase 1/2 study of TRK-950 in patients with advanced solid tumors, including melanoma, that…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy [Phase 1, Phase 2]
Clinical trial evaluating oral 7HP349 (Alintegimod) in combination with ipilimumab, followed by nivolumab monotherapy, in patients with adva…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis [EARLY_Phase 1]
An EARLY Phase 1 trial evaluating RP1 in primary melanoma to reduce the risk of sentinel lymph node metastasis; the study is currently recru…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies [Phase 1]
Phase 1 trial update evaluating cediranib maleate and selumetinib sulfate in patients with solid malignancies, including metastatic melanoma…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07) [Phase 2]
A Phase 2 trial evaluating Acasunlimab alone and in combination with pembrolizumab for advanced melanoma that has relapsed after prior check…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: CD8+ T Cell Imaging During Pre-surgery Immunotherapy in People With Melanoma [Phase 2]
This update describes a Phase 2 clinical trial investigating CD8+ T cell imaging during pre-surgery immunotherapy in people with melanoma. T…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS) [Phase 1]
Phase 1 study of ADP-A2M4CD8 as monotherapy or in combination with nivolumab or pembrolizumab in HLA-A2+ patients with MAGE-A4-positive tumo…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: PROSECCO: A Phase 2, Single Arm, Neoadjuvant Study Evaluating Combination Cemiplimab, Fianlimab, And Ipilimumab In Patients With Surgically Resectable Melanoma [Phase 2]
This document describes a Phase 2, single-arm neoadjuvant trial of cemiplimab, fianlimab, and ipilimumab in surgically resectable melanoma. …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metastases [NA]
Clinical trial update on a Gallium-68 labeled PSMA PET/CT tracer being studied to differentiate radiation necrosis from tumor progression in…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants [Phase 1]
Phase 1 study evaluating autologous tumor-infiltrating lymphocytes in pediatric, adolescent, and young adult participants with soft tissue s…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy [NA]
A clinical trial update comparing single-dose versus multiple-dose radiation in cancer patients with brain metastases who are receiving immu…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain [Phase 3]
Phase 3 trial comparing longer-duration radiation therapy versus standard radiation therapy for patients with cancer that has spread to the …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. [Phase 3]
Phase 3 trial evaluating lifileucel plus pembrolizumab versus pembrolizumab alone in untreated advanced melanoma (metastatic/unresectable); …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma [Phase 1]
Phase 1 clinical trial comparing pharmacokinetics, safety, and immunogenicity of Biocon Biologics' Bmab1700 versus Opdivo (nivolumab) as adj…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Testing the Addition of the Anti-cancer Drug, Tazemetostat, to the Usual Treatment (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment [Phase 1, Phase 2]
A Phase 1/2 trial is evaluating whether adding tazemetostat to dabrafenib and trametinib improves outcomes in patients with metastatic melan…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease [Phase 1]
Phase 1 study evaluating intravenous and intrathecal nivolumab for leptomeningeal disease in melanoma and non-small cell lung cancer patient…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients [Phase 2]
Phase 2 trial evaluating a sequence of interleukin-2 with ipilimumab followed by nivolumab for stage III or IV melanoma; currently recruitin…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers [Phase 1]
Phase 1 clinical trial update for PF-08046032 in people with advanced cancers; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma [Phase 2]
A Phase 2 neoadjuvant and adjuvant trial evaluating anti-PD1 therapy alone or in combinations for locoregionally advanced melanoma is curren…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial [NA]
The DUO Trial is studying whether combining high-intensity exercise with a high-fiber diet affects immunotherapy outcomes in melanoma patien…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Zimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory Melanoma [Phase 2]
Phase 2 trial update of zimberelimab (AB122) with domvanalimab (AB154) in PD-1 relapsed/refractory melanoma; the study is currently active b…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours [Phase 1, Phase 2]
Ipsen is conducting a Phase 1/2 trial of IPN01194 as a single-agent therapy for adults with advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating CD40L-augmented tumor-infiltrating lymphocytes for advanced melanoma is currently recruiting.