Melanoma
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CLINICAL_TRIALS research · 2013-02-04Clinical Trial Update: A Phase II Study of Imatinib Versus Interferon as Adjuvant Therapy in KIT-mutated Melanoma [Phase 2]
Phase II randomized trial comparing imatinib to interferon as adjuvant therapy for KIT-mutated melanoma; the document provides a trial statu…
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CLINICAL_TRIALS research · 2012-10-10Clinical Trial Update: Safety and Toxicity Study of Vaccination for Advanced Metastatic Melanoma Patients [Phase 1, Phase 2]
This clinical trial update describes a vaccination therapy being evaluated for safety and toxicity in patients with advanced/metastatic mela…
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CLINICAL_TRIALS research · 2012-09-07Clinical Trial Update: In-vivo Optical Coherence Tomography Imaging in Dermatooncology
This trial update discusses the use of in-vivo optical coherence tomography (OCT) imaging to study dermatooncology lesions, including melano…
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CLINICAL_TRIALS research · 2012-09-03Clinical Trial Update: The Value of Preoperative Dynamic Lymphscintigraphy and Ultrasoundscanning, Eventually With FNA, for Identification of Malignant Sentinel Node(s) in Patients With Melanoma [NA]
Clinical trial update on using preoperative dynamic lymphoscintigraphy and ultrasound (with FNA if needed) to identify malignant sentinel ly…
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CLINICAL_TRIALS research · 2012-06-07Clinical Trial Update: Phase I and Consecutive Phase II, Two-arm, Randomized Multi-center Trial in Patients With Advanced Melanoma [Phase 1, Phase 2]
Two-arm, randomized Phase I/II study in advanced melanoma conducted at multiple centers (University of Regensburg). The current status is UN…
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CLINICAL_TRIALS research · 2012-04-25Clinical Trial Update: Clinical Trial of a Therapeutic Vaccine With NY-ESO-1 in Combination With the Adjuvant Monophosphoryl Lipid A (MPLA) [Phase 1, Phase 2]
This entry describes a Phase 1/2 clinical trial of an NY-ESO-1–based therapeutic vaccine with the MPLA adjuvant, evaluated in melanoma, ovar…
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CLINICAL_TRIALS research · 2012-02-13Clinical Trial Update: A Study of Transgenic Lymphocyte Immunization (TLI) Against Telomerase in Subjects With Stage III Melanoma [Phase 2]
A Phase 2 clinical trial update for transgenic lymphocyte immunization targeting telomerase in stage III melanoma patients (Stage IIIB/IIIC)…
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CLINICAL_TRIALS research · 2011-11-16Clinical Trial Update: High-Dose or Low-Dose Interferon Alfa Compared With No Further Therapy Following Surgery in Treating Patients With Stage III Melanoma [Phase 3]
Phase 3 trial evaluating high-dose or low-dose interferon alfa versus no further therapy after surgery for stage III melanoma; current statu…
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CLINICAL_TRIALS research · 2011-11-08Clinical Trial Update: Tesetaxel as Second-line Therapy for Patients With Advanced Melanoma and Normal Serum LDH [Phase 2]
A Phase 2 clinical trial update evaluating tesetaxel as second-line therapy for patients with advanced melanoma and normal serum LDH.
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CLINICAL_TRIALS research · 2011-08-04Clinical Trial Update: TACE With Drug Eluting Beads Loaded With Doxorubicin in Liver Metastases From Melanoma Patients [Phase 1, Phase 2]
Clinical trial evaluating transarterial chemoembolization using drug-eluting beads loaded with doxorubicin. The trial targets unresectable l…
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CLINICAL_TRIALS research · 2011-01-24Clinical Trial Update: Role of SLURP-1 in Melanoma and Melanoma Stem Cells
This entry summarizes a clinical trial investigating the role of SLURP-1 in melanoma and melanoma stem cells. The status of the trial is unk…
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CLINICAL_TRIALS research · 2010-10-18Clinical Trial Update: A Survey Study to See if Patients Diagnosed With Parkinson's Disease Have Higher Incidence of Melanoma
A completed survey study investigating whether patients with Parkinson's disease have a higher incidence of melanoma.
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CLINICAL_TRIALS research · 2010-10-07Clinical Trial Update: Sorafenib and Temozolomide in Treating Patients With Stage III or Stage IV Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of Sorafenib and Temozolomide in patients with stage III or stage IV melanoma.
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CLINICAL_TRIALS research · 2010-04-26Clinical Trial Update: Long-term Data Collection for Subjects in MDX-010 Studies
An update indicating ongoing long-term data collection for subjects enrolled in MDX-010 studies (ipilimumab) for metastatic melanoma.
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CLINICAL_TRIALS research · 2009-12-08Clinical Trial Update: Safety Study of Combined Chemotherapy and Endostar to Untreated Patients With Advanced Melanoma [Phase 2]
A Phase 2 safety study evaluating the combination of chemotherapy and Endostar in untreated patients with advanced melanoma.
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CLINICAL_TRIALS research · 2009-10-27Clinical Trial Update: The Identification of Novel Prognostic Markers in Melanoma
This document reports a clinical trial update focused on identifying novel prognostic markers in melanoma.
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CLINICAL_TRIALS research · 2009-06-03Clinical Trial Update: Evaluation of the Effects of Local Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Adjuvant Administration on Dendritic Cells in Skin of Melanoma Patients and in Sentinel Lymph Nodes: MEL38 [NA]
A completed clinical trial (MEL38) evaluated local GM-CSF as an adjuvant in melanoma patients, analyzing dendritic cell effects in the skin …
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CLINICAL_TRIALS research · 2007-12-06Clinical Trial Update: Randomized Trial of ATN-224 and Temozolomide in Advanced Melanoma [Phase 2]
Clinical trial update for a Phase 2 randomized study of ATN-224 in combination with temozolomide in advanced melanoma; current status is unk…
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CLINICAL_TRIALS research · 2006-12-06Clinical Trial Update: Melanoma Inhibitory Activity (MIA): A Serological Marker for Metastatic Uveal Melanoma
This clinical trial update discusses Melanoma Inhibitory Activity (MIA) as a serological marker for metastatic uveal melanoma. The sponsor i…
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CLINICAL_TRIALS research · 2006-06-21Clinical Trial Update: Standard Palliative Care Versus Standard Palliative Care Plus Polychemotherapy in Metastasized Malignant Melanoma [Phase 4]
An ongoing Phase 4 trial compares standard palliative care alone versus standard palliative care plus polychemotherapy in metastatic melanom…