Melanoma
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Intratumoral Targeted Hyperthermia Therapy (THT) for Stage 3C/3D/4M1 Cutaneous Metastatic Melanoma [NA]
This ClinicalTrials.gov entry describes a trial evaluating intratumoral targeted hyperthermia therapy (THT) for stage 3C/3D/4M1 cutaneous me…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Perioperative Treatment With Tranexamic Acid in Melanoma [Phase 3]
This document details a Phase 3 clinical trial evaluating perioperative tranexamic acid in patients with melanoma that is currently recruiti…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Real-life Pharmacological Monitoring of Encorafenib-Binimetinib in the Treatment of Metastatic Melanoma
A real-world pharmacological monitoring study of the encorafenib and binimetinib combination for metastatic melanoma is currently recruiting…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: A Phase I/ II Study of Fragmented Autoantigen Stimulated T-cell-immunotherapy Combined with Radiotherapy (FAST-CR) [EARLY_Phase 1]
Phase I/II study of Fragmented Autoantigen Stimulated T-cell-immunotherapy (FAST-CR) combined with radiotherapy. The trial targets breast ca…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: In Vivo Liquid Biopsy of Melanoma (Cytophone) [NA]
Registration indicates a Cytophone-based in vivo liquid biopsy trial for melanoma evaluating circulating tumor cells, including metastatic m…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: FMT to Convert Response to Immunotherapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial at The Netherlands Cancer Institute is evaluating fecal microbiota transplant to convert response to immunotherap…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Improving Early Detection of Melanoma Recurrence With Circulating Tumor DNA (ctDNA)
A clinical trial update exploring the use of circulating tumor DNA (ctDNA) to detect melanoma recurrence earlier than current methods.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Assessment of Circulating Tumor Cells and microRNAs in Patients With Metastatic Non-cutaneous Melanoma
This clinical trial update describes an ongoing study evaluating circulating tumor cells and microRNAs in patients with metastatic melanoma,…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Review of the Literature and Serie of Patients Who Underwent Reconstruction After Wide Local Excision of Nail Apparatus for Melanoma
A review of the literature and a case series of patients who underwent reconstruction after wide local excision of nail apparatus melanoma.
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Fluzoparib in Combination With Camrelizumab and Temozolomide in Advanced Melanoma [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating Fluzoparib in combination with Camrelizumab and Temozolomide for advanced melanoma and is currently…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Precision Radiation of Immune Checkpoint Therapy Resistant Melanoma Metastases [NA]
Clinical trial update describing a study investigating precision radiation for metastatic melanoma that has become resistant to immune check…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: WoW - Single- vs Two-staged Excisions of Thin Melanoma [NA]
Clinical trial investigating single- versus two-staged excisions for thin melanoma; the study is currently recruiting in the Vastra Gotaland…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Camrelizumab Plus Apatinib and Temozolomide as Neoadjuvant in High Risk Acral Melanoma [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant study of camrelizumab plus apatinib and temozolomide in high-risk acral melanoma …
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Observational Study of Patients With Advanced Melanoma (Skin Cancer) to Assess if IOpener®-Melanoma Test Can Predict Response to Immunotherapy.
An observational clinical trial update evaluating whether the IOpener-Melanoma Test can predict response to immunotherapy in patients with a…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Precision Medicine for L/GCMN and Melanoma 1
This clinical trial update describes a precision medicine study for large/giant congenital melanocytic nevus (L/GCMN) and melanoma, and the …
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Safe Stop Ipilimumab-nivolumab (IPI-NIVO) Trial [NA]
Clinical trial update indicates the Ipilimumab-nivolumab (IPI-NIVO) combination trial for melanoma (stage III/IV) is currently recruiting at…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Precision Medicine for L/GCMN and Melanoma 2
A clinical trial update indicates a precision medicine study for large/giant congenital melanocytic nevus and melanoma is currently recruiti…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma [Phase 3]
This update describes a Phase 3 trial evaluating BCD-217 (Nurulimab + Proglolimab) followed by anti-PD-1 therapy versus anti-PD-1 monotherap…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Understanding the Transition from Normal Melanocytes to Nevus to Melanoma
This clinical trial update describes a study on the transition from normal melanocytes to nevi to melanoma, sponsored by Fundacion Clinic pe…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Ex VIvo DEtermiNed Cancer Therapy
An ongoing clinical trial for an Ex Vivo Determined Cancer Therapy is currently recruiting and spans multiple cancers, including bladder and…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists [NA]
A clinical trial update aimed at identifying predictive factors of response to PD-1/PD-L1 inhibitors across multiple cancers, including mela…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma [Phase 2]
Phase 2 neoadjuvant trial evaluating PD-1 blockade in patients with stage IIB/C melanoma is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: A Prospective Study of Plasma Genotyping as a Noninvasive Biomarker for Genotype-directed Cancer Care
This entry describes a prospective clinical trial evaluating plasma genotyping as a noninvasive biomarker to guide genotype-directed cancer …
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Genomic Investigation of Unusual Responders
This clinical trial update describes a University Health Network study investigating genomic factors in unusual responders across multiple c…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL) [Phase 2]
Phase 2 clinical trial evaluating a pragmatic adoptive cell therapy approach using an IL2 analog (ANV419) versus high-dose IL-2 after tumor-…