Medulloblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs [Phase 1, Phase 2]
Phase I/II trial of decitabine with a vaccine therapy in relapsed/refractory pediatric high-grade gliomas, medulloblastoma, and CNS primitiv…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor [Phase 1]
Phase 1 trial evaluating autologous dendritic cells loaded with brain tumor stem cells for progressive malignant brain tumors has completed.
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CLINICAL_TRIALS withdrawal · 2017-08-25Clinical Trial Update: Dosimetry Guided PRRT With 90Y-DOTATOC [Phase 2]
A Phase 2 trial evaluating dosimetry-guided peptide receptor radionuclide therapy using 90Y-DOTATOC has been withdrawn. The study covered ne…
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CLINICAL_TRIALS trial_result · 2017-08-21Clinical Trial Update: Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma [NA]
A completed clinical trial evaluating proton beam radiation therapy in young patients after biopsy or surgery for medulloblastoma or pineobl…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors [Phase 1]
This Phase 1 trial tests the safety of the p28 peptide in younger patients with recurrent or progressive central nervous system tumors and t…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma [Phase 3]
Phase 3 trial comparing different radiation therapy regimens in combination with chemotherapy for young patients with newly diagnosed standa…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) [Phase 2]
Phase II study evaluating oral LDE225 (sonidegib) in Hedge-Hog pathway-activated relapsed medulloblastoma; the trial completed with results …
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma [Phase 3]
Phase 3 trial evaluating radiation therapy regimens with chemotherapy in newly diagnosed standard-risk medulloblastoma in young patients; re…
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CLINICAL_TRIALS withdrawal · 2017-04-28Clinical Trial Update: Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors [NA]
A clinical trial evaluating 68Ga-DOTATOC PET-CT for brain tumors in children and young adults has been withdrawn from the study.
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases [NA]
A clinical trial comparing gadobutrol to gadopentetate dimeglumine or gadobenate dimeglumine before DCE-MRI in patients with multiple sclero…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma [Phase 1]
Phase 1 trial update reporting results for TPI-287 in patients with refractory or recurrent neuroblastoma or medulloblastoma. The study stat…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma [Phase 1, Phase 2]
Phase 1/2 safety and efficacy study of TPI-287 in neuroblastoma and medulloblastoma was terminated. Results were posted on 2016-10-28.
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CLINICAL_TRIALS research · 2016-08-17Clinical Trial Update: Radiation Therapy and Combination Chemotherapy for Medulloblastoma [Phase 2]
This is an update on a Phase 2 clinical trial evaluating radiation therapy in combination with chemotherapy for medulloblastoma.
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB [Phase 1, Phase 2]
Phase I dose-finding and safety study of LDE225 (sonidegib) in children with recurrent or refractory medulloblastoma, with a Phase II portio…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma [Phase 2]
Phase 2 study of vismodegib in adults with recurrent or refractory medulloblastoma completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma [Phase 2]
Phase 2 results for vismodegib in younger patients with recurrent or refractory medulloblastoma have been posted.
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CLINICAL_TRIALS withdrawal · 2015-05-22Clinical Trial Update: Valproic Acid in Childhood Progressive Brain Tumors [Phase 1]
The trial withdrawal notice states that the Phase 1 study of valproic acid for childhood progressive brain tumors has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia [Phase 1]
Phase 1 study of RO4929097, a gamma-secretase inhibitor, in pediatric patients with relapsed or refractory solid tumors, CNS tumors, lymphom…
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CLINICAL_TRIALS trial_result · 2014-08-01Clinical Trial Update: Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma [Phase 3]
A Phase 3 trial investigated radiation therapy plus combination chemotherapy in children with medulloblastoma; the study has completed.
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma [Phase 2]
Phase 2 trial evaluating etoposide plus radiation therapy followed by combination chemotherapy in children with newly diagnosed advanced med…
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors [Phase 2]
Phase 2 clinical trial evaluating combination chemotherapy followed by bone marrow or peripheral stem cell transplantation in patients with …
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma [Phase 3]
A Phase 3 clinical trial update investigates radiation therapy plus combination chemotherapy for children with medulloblastoma; the current …
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment [Phase 1]
A Phase 1 study evaluating GDC-0449 (vismodegib) in young patients with recurrent or treatment-refractory medulloblastoma has been completed…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor [Phase 3]
Phase 3 clinical trial evaluating treatment for newly diagnosed medulloblastoma, supratentorial PNET, or atypical teratoid rhabdoid tumor; s…