Medulloblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET [Phase 3]
A Phase 3 clinical trial update reports on chemotherapy and radiation therapy for newly diagnosed high-risk medulloblastoma/PNET in young pa…
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET [Phase 3]
Phase 3 clinical trial evaluating chemotherapy and radiation therapy in newly diagnosed, high-risk medulloblastoma/PNET in young patients ha…
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CLINICAL_TRIALS trial_result · 2020-03-31Clinical Trial Update: Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults [Phase 1, Phase 2]
Multicenter pilot study in adults with medulloblastoma completed, evaluating a therapy across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-12-10Clinical Trial Update: A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors [Phase 2]
Phase 2 trial evaluating pomalidomide monotherapy in children and young adults with recurrent or progressive primary brain tumors, including…
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors [Phase 2]
Phase 2 trial evaluating temozolomide and irinotecan with or without bevacizumab in young patients with recurrent or refractory medulloblast…
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma [Phase 2]
Phase 2 trial evaluating low-dose radiation plus combination chemotherapy after surgery in children with newly diagnosed medulloblastoma; st…
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CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma [Phase 2]
Phase 2 trial update exploring combination chemotherapy in younger patients with newly diagnosed, non-metastatic desmoplastic medulloblastom…
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CLINICAL_TRIALS trial_result · 2018-10-24Clinical Trial Update: Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma [Phase 3]
This Phase 3 clinical trial evaluated upfront combination chemotherapy followed by peripheral stem cell transplant in children with newly di…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children [Phase 2, Phase 3]
This document is an update on a Phase 2/Phase 3 therapy optimization trial for relapsed or refractory pediatric brain tumors, which has comp…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing plerixafor after radiation therapy and temozolomide in newly diagnosed high-grade glioma has completed wi…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Yoga Therapy in Treating Patients With Malignant Brain Tumors [NA]
This entry notes a terminated clinical trial at Wake Forest evaluating yoga therapy for adults with malignant brain tumors.
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs [Phase 1, Phase 2]
Phase I/II trial of decitabine with a vaccine therapy in relapsed/refractory pediatric high-grade gliomas, medulloblastoma, and CNS primitiv…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor [Phase 1]
Phase 1 trial evaluating autologous dendritic cells loaded with brain tumor stem cells for progressive malignant brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2017-08-21Clinical Trial Update: Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma [NA]
A completed clinical trial evaluating proton beam radiation therapy in young patients after biopsy or surgery for medulloblastoma or pineobl…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors [Phase 1]
This Phase 1 trial tests the safety of the p28 peptide in younger patients with recurrent or progressive central nervous system tumors and t…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma [Phase 3]
Phase 3 trial comparing different radiation therapy regimens in combination with chemotherapy for young patients with newly diagnosed standa…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) [Phase 2]
Phase II study evaluating oral LDE225 (sonidegib) in Hedge-Hog pathway-activated relapsed medulloblastoma; the trial completed with results …
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma [Phase 3]
Phase 3 trial evaluating radiation therapy regimens with chemotherapy in newly diagnosed standard-risk medulloblastoma in young patients; re…
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases [NA]
A clinical trial comparing gadobutrol to gadopentetate dimeglumine or gadobenate dimeglumine before DCE-MRI in patients with multiple sclero…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma [Phase 1]
Phase 1 trial update reporting results for TPI-287 in patients with refractory or recurrent neuroblastoma or medulloblastoma. The study stat…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma [Phase 1, Phase 2]
Phase 1/2 safety and efficacy study of TPI-287 in neuroblastoma and medulloblastoma was terminated. Results were posted on 2016-10-28.
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB [Phase 1, Phase 2]
Phase I dose-finding and safety study of LDE225 (sonidegib) in children with recurrent or refractory medulloblastoma, with a Phase II portio…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma [Phase 2]
Phase 2 study of vismodegib in adults with recurrent or refractory medulloblastoma completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma [Phase 2]
Phase 2 results for vismodegib in younger patients with recurrent or refractory medulloblastoma have been posted.