Mania
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-22Clinical Trial Results: Aripiprazole Pharmacokinetics (PK) and Tolerability Study in Children and Adolescents [Phase 1]
Phase 1 pharmacokinetics and tolerability study of aripiprazole in children and adolescents with schizophrenia or mania completed; results p…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine [Phase 3]
Phase 3 trial evaluating adjunctive KarXT (xanomeline/trospium) for mania in adults with Bipolar I Disorder on lithium, valproate, or lamotr…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania [Phase 2]
Phase 2 clinical trial assessing efficacy, safety, and pharmacokinetics of NBI-1117568 in adults with Bipolar I Disorder experiencing mania;…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Clocks in Sync - Circadian Rhythm and Bipolar Mania [NA]
A completed clinical trial from the Ottawa Hospital Research Institute examining circadian rhythm in bipolar mania.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features [Phase 3]
A Phase 3 trial evaluating cariprazine for preventing relapse in Bipolar I Disorder patients currently in manic or depressive episodes (with…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: A Study of the Efficacy and Safety of Intramuscular Ziprasidone Followed by Oral Ziprasidone for the Treatment of Psychosis [Phase 4]
Phase 4 trial updating the efficacy and safety of intramuscular ziprasidone followed by oral ziprasidone for psychosis in schizophrenia/mani…
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CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Participants With Bipolar I Disorder. [Phase 3]
Phase 3 trial evaluating the safety and tolerability of brexpiprazole in adults with Bipolar I Disorder and acute mania has completed with r…
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CLINICAL_TRIALS trial_result · 2019-03-01Clinical Trial Update: Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study [Phase 2]
Phase 2 double-blind, placebo-controlled trial evaluating taurine as an anti-manic agent in bipolar disorder with mania.
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: Treatment of Bipolar Mania in Older Adults [Phase 4]
Phase 4 clinical trial update on treatments for bipolar mania in older adults; results posted after completion.
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CLINICAL_TRIALS withdrawal · 2018-07-20Clinical Trial Update: Open-Label Study of Latuda for the Treatment of Mania in Children and Adolescents 6-17 Years Old [Phase 4]
Open-label Phase 4 study of lurasidone (Latuda) for mania in youths aged 6-17 was withdrawn.
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CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: Allopurinol Maintenance Study for Bipolar Disorder [Phase 4]
A Phase 4 clinical trial evaluating maintenance allopurinol for bipolar disorder has been terminated; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Safety and Efficacy of Cariprazine for Mania [Phase 3]
Phase 3 trial results assessing the safety and efficacy of cariprazine for mania in bipolar disorder.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Safety and Efficacy of Cariprazine for Bipolar I Disorder [Phase 3]
Phase 3 trial assessing the safety and efficacy of cariprazine for Bipolar I Disorder with mania; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Efficacy of Allopurinol and Dypiridamole in Acute Mania [Phase 4]
Phase 4 clinical trial evaluating the efficacy of allopurinol and dipyridamole in acute mania has completed.
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Methylphenidate for the Treatment of Acute Mania [Phase 3]
A Phase 3 clinical trial evaluating methylphenidate for the treatment of acute mania has completed.
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Neurochemical Effects of Omega-3 Fatty Acids in Adolescents at Risk for Mania [Phase 2]
A Phase 2 trial evaluating neurochemical effects of omega-3 fatty acids in adolescents at risk for mania has completed with results posted.
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: Virtual Darkness as Additive Treatment in Mania [NA]
A completed clinical trial evaluating virtual darkness as an additive treatment for mania in bipolar disorder.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Peroxisomal Defects and Familial Risk for Bipolar Disorder
A completed clinical trial from the University of Cincinnati investigated peroxisomal defects and familial risk factors for bipolar disorder…
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Effects of Pentazocine Versus Lorazepam on Manic Symptoms [Phase 2]
Phase 2 trial comparing pentazocine to lorazepam for manic symptoms in bipolar and schizoaffective disorders; results posted after completio…
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CLINICAL_TRIALS trial_result · 2014-08-11Clinical Trial Update: Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/Dependence [Phase 3]
A Phase 3 trial evaluating citicoline therapy in mania/hypomania with cocaine use disorder has completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: Study of Depakote ER for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder [Phase 4]
Phase 4 trial evaluating Depakote ER for mania in children aged 6-12 with bipolar disorder; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder [Phase 4]
Aripiprazole was studied in a Phase 4 clinical trial for treating mania in children and adolescents with bipolar disorder, and the study sta…
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CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: Ziprasidone for the Treatment of Mania in Children and Adolescents With Bipolar Disorder [Phase 4]
Phase 4 trial of ziprasidone for mania in children and adolescents with bipolar disorder has completed; the update summarizes pediatric effi…
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CLINICAL_TRIALS trial_result · 2013-05-06Clinical Trial Update: Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder [Phase 4]
This document reports the completion of a Phase 4 trial comparing risperidone to olanzapine for mania in preschool children aged 4 to 6 with…
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CLINICAL_TRIALS trial_result · 2012-05-08Clinical Trial Update: Allopurinol for Mania: A Randomized Trial Administering Allopurinol vs. Placebo as add-on to Mood Stabilizers and/or Antipsychotics in Patients in a Bipolar Manic Episode [Phase 3]
A Phase 3 randomized trial evaluated allopurinol as an add-on to mood stabilizers/antipsychotics for mania in bipolar disorder; the study ha…