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CLINICAL_TRIALS research · 2026-04-23

Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine [Phase 3]

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Summary

Phase 3 trial evaluating adjunctive KarXT (xanomeline/trospium) for mania in adults with Bipolar I Disorder on lithium, valproate, or lamotrigine. Recruitment i…

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Diseases / indications

Drugs mentioned

  • KarXT (xanomeline-trospium)

Snippet

Sponsor: Bristol-Myers Squibb | Conditions: Mania, Bipolar Disorder | Phase 3 | Status: RECRUITING