Malignant Solid Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial) [Phase 2]
Phase 2 ComboMATCH trial evaluating AMG 510 (sotorasib) with panitumumab for KRAS G12C-mutant solid tumors; currently active but not recruit…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer [Phase 1]
This clinical trial update describes a Phase 1 study investigating the combination of trastuzumab deruxtecan (DS-8201a) and olaparib in HER2…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating the safety and potential efficacy of combining ZEN003694 with abemaciclib in adults and 12-17-year-old ped…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating the combination of ZEN003694 with nivolumab, with or without ipilimumab, in metastatic and recurrent solid…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma [Phase 1]
A Phase 1 clinical trial is evaluating the three-drug combination of Copanlisib, Nivolumab, and Ipilimumab in patients with advanced cancer …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors [Phase 1]
Clinical trial update detailing a Phase 1 safety study of GEN1042 in Japanese subjects with malignant solid tumors, currently active but not…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer [Phase 3]
Phase 3 clinical trial evaluating triptorelin to prevent chemotherapy-induced ovarian damage in adolescents and young adults with cancer is …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors [Phase 1]
This update notes that ISM6331 is being studied in a Phase 1 trial with recruitment ongoing for participants with malignant mesothelioma and…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I) [Phase 2]
Phase 2 MATCH subprotocol Z1I study evaluating AZD1775 (adavosertib) as a targeted treatment for cancers with BRCA genetic changes. The tria…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors [EARLY_Phase 1]
An early-phase trial is evaluating the safety and tolerability of ex vivo next-generation neoantigen-selected tumor-infiltrating lymphocyte …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: To Evaluate the Phase I Clinical Study of JSKN016 in Chinese Patients With Advanced Malignant Solid Tumors [Phase 1]
This clinical trial update announces the Phase I study of JSKN016 in Chinese patients with advanced malignant solid tumors and indicates rec…