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CLINICAL_TRIALS research · 2026-04-24

Clinical Trial Update: Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial) [Phase 2]

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Summary

Phase 2 ComboMATCH trial evaluating AMG 510 (sotorasib) with panitumumab for KRAS G12C-mutant solid tumors; currently active but not recruiting.

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Diseases / indications

Drugs mentioned

  • LUMAKRAS (sotorasib)
  • Vectibix (panitumumab)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm | Phase 2 | Status: ACTIVE_NOT_RECRUITING