Malignant Pleural Effusion
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
A completed Travera Inc trial evaluating TraveraRTGx and a tumor-cell biomarker intended to guide rapid therapy decisions across multiple ca…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Furmonertinib Plus Radiotherapy for EGFR+ NSCLC With Pleural Effusion [Phase 2]
Phase 2 clinical trial evaluating furmonertinib plus radiotherapy for EGFR-positive non-small cell lung cancer with malignant pleural effusi…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: PMCF Study of the CE-marked Drainova® ArgentiC Catheter
This PMCF study of the CE-marked Drainova ArgentiC Catheter by ewimed GmbH has completed. It evaluated its use for pleural effusion (includi…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions [NA]
A pilot study evaluating the safety and effectiveness of a new pleural catheter for symptomatic, recurrent malignant pleural effusions; the …
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy [NA]
MD Anderson's NCT03868579 evaluated rapid on-site evaluation of pleural touch preparations during pleuroscopy to diagnose malignant pleural …
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion [Phase 4]
A Phase 4 study comparing thoracoscopic talc pleurodesis versus a bleomycin-tranexamic acid mixture injected via chest tube for malignant pl…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural Effusion [EARLY_Phase 1]
The document reports an early-phase trial update on the outcome of inserting an intercostal tube or performing pleurodesis to treat malignan…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Quantitative C-Reactive Protein for Differentiating Tuberculous and Malignant Pleural Effusion: a Cross-Sectional Study
This cross-sectional study evaluated whether quantitative C-reactive protein can differentiate tuberculous pleural effusion from malignant p…
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CLINICAL_TRIALS trial_result · 2024-01-26Clinical Trial Update: Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesothelioma [Phase 1, Phase 2]
A clinical trial update for RSO-021 in malignant pleural effusion due to advanced/metastatic solid tumors including mesothelioma across Phas…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion [Phase 4]
Phase 4 randomized trial evaluating talc instillation plus daily drainage via tunneled pleural catheter for outpatient pleurodesis in malign…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions [Phase 3]
Phase 3 trial investigating bleomycin, doxycycline, or talc for treating malignant pleural effusions has completed.
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CLINICAL_TRIALS trial_result · 2022-09-02Clinical Trial Update: Tunneled Pleural Catheter in Partially Entrapped Lung [Phase 2]
Phase 2 clinical trial update evaluating a tunneled pleural catheter in patients with malignant pleural effusion.
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CLINICAL_TRIALS trial_result · 2022-04-15Clinical Trial Update: A Study of Intrapleural Administration of Bevacizumab and Camrelizumab for Malignant Pleural Effusion [Phase 1, Phase 2]
A combined Phase 1/2 clinical trial evaluating intrapleural administration of bevacizumab and camrelizumab for malignant pleural effusion is…
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion [Phase 1, Phase 2]
Phase 1/2 trial of nivolumab plus intrapleural talimogene laherparepvec for malignant pleural effusion has been terminated with results post…
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population [Phase 2]
A Phase 2 clinical trial evaluating the effectiveness of doxycycline for treating malignant pleural effusions in an outpatient population.
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CLINICAL_TRIALS trial_result · 2020-08-13Clinical Trial Update: Safety and Effectiveness of a New Pleural Catheter for Symptomatic, Recurrent, MPEs Versus Approved Pleural Catheter [NA]
A completed clinical trial evaluated a new pleural catheter for symptomatic, recurrent malignant pleural effusions against an approved cathe…
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CLINICAL_TRIALS trial_result · 2020-01-23Clinical Trial Update: Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion [Phase 3]
Phase 3 trial comparing iodopovidone to talc for palliation in malignant pleural effusion has completed.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis [Phase 4]
Phase 4 trial comparing doxycycline versus saline for pleurodesis via indwelling pleural catheter in patients with malignant pleural effusio…
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CLINICAL_TRIALS trial_result · 2019-06-14Clinical Trial Update: A Randomized Study of Primary Tumor Radiotherapy for Patients With MPE Stage IV NSCLC [Phase 2]
A Phase 2 randomized study evaluating primary tumor radiotherapy for patients with malignant pleural effusion in stage IV non-small cell lun…
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CLINICAL_TRIALS trial_result · 2019-03-29Clinical Trial Update: Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating intrapleural bevacizumab for malignant pleural effusion in non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2019-03-08Clinical Trial Update: Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer [Phase 2]
Phase 2 clinical trial investigating intrapleural docetaxel administration via medical pleuroscopy for malignant pleural effusion in non-sma…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion [Phase 2]
Phase 2 clinical trial evaluating tumor cell-derived microparticles carrying chemotherapeutic drugs for malignant pleural effusion.
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CLINICAL_TRIALS trial_result · 2018-12-20Clinical Trial Update: Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis [Phase 1, Phase 2]
Clinical trial updating the management of malignant pleural effusion comparing indwelling pleural catheter versus silver nitrate pleurodesis…
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CLINICAL_TRIALS trial_result · 2018-11-08Clinical Trial Update: A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites [Phase 1, Phase 2]
A clinical trial update for Syngenon (BSG-001) in inhalation therapy for malignant pleural effusion and malignant ascites across Phase 1 and…
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: Bevacizumab in the Treatment of Malignant Pleural Effusions of Non-squamous Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating bevacizumab for malignant pleural effusions in patients with non-squamous non-small cell lung cancer.