Malignant Pleural Effusion
📧 Sign up to get email alerts when something new happens for Malignant Pleural Effusion.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Intrapleural Catheter Daily Versus Three Times a Week Drainage [Phase 2]
This Phase 2 trial update compares daily intrapleural catheter drainage with drainage three times a week in patients with advanced cancer an…
-
CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors [Phase 1]
Phase 1 trial evaluating Fast TILs, a tumor-infiltrating lymphocyte therapy, for malignant pleural effusions arising from epithelial or meso…
-
CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions
A clinical trial evaluating indwelling pleural catheters with or without doxycycline for malignant pleural effusions due to pleural neoplasm…
-
CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions [NA]
This document outlines an ongoing clinical trial comparing pleuroscopy first versus thoracentesis first in patients with suspected malignant…
-
CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease [Phase 1]
Phase 1 clinical trial evaluating rapid expansion of tumor-infiltrating lymphocytes (TILs) to treat metastatic pleural disease, including ma…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion [Phase 1, Phase 2]
This early-phase study investigates intrapleural administration of toluene sulfonamide in patients with malignant pleural effusions, includi…
-
CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis [NA]
A clinical trial update comparing talc slurry and talc insufflation for pleurodesis, noting the study is not yet recruiting and will evaluat…
-
CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions [Phase 3]
Phase 3 trial evaluating systemic cisplatin added to intracavitary cisplatin versus placebo with intracavitary cisplatin for malignant pleur…
-
CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion [EARLY_Phase 1]
This source reports an early-phase 1 trial evaluating alteplase delivered through an indwelling pleural catheter to manage symptomatic septa…
-
CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Pleurodesis in Small-bore Chest Tube [NA]
The University of Hong Kong is conducting a trial on pleurodesis via small-bore chest tube for malignant pleural effusion. The study status …
-
CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Biomarker Levels During Indwelling Pleural cAtheter Sample Testing
This clinical trial update reports on biomarker level testing in samples from indwelling pleural catheters for malignant pleural effusions. …
-
CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: UNC Pleural Fluid Registry
UNC Pleural Fluid Registry trial is currently recruiting to collect pleural fluid data from patients with several conditions including lung …
-
CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: The Experiences of Patients Living With Malignant Pleural Effusions
This clinical trial update reports on the experiences of patients living with malignant pleural effusion; the study is completed.
-
CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound [NA]
A clinical trial at Ain Shams University is recruiting to evaluate whether patient rotation affects the success and patient comfort of chemi…
-
CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Impact of Pleural Manometry on the Assessment and Treatment of Malignant Pleural Effusion: A Pilot Clinical Trial [NA]
Pilot clinical trial evaluating the impact of pleural manometry on the assessment and management of malignant pleural effusion; the study is…
-
CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Bevacizumab Combined With Cisplatin Versus Cisplatin Monotherapy in Malignant Serous Effusions [Phase 2]
A Phase 2 trial comparing bevacizumab plus cisplatin against cisplatin alone for malignant serous effusions is currently recruiting.
-
CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC [Phase 1, Phase 2]
This entry announces an ongoing Phase Ib/II trial of M701 for malignant pleural effusions caused by non-small cell lung cancer (stage IV), c…
-
CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer [Phase 1]
Phase 1 trial evaluating delivery of tocilizumab via pleural and peritoneal catheters in patients with advanced metastatic cancer, including…
-
CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion [NA]
A clinical trial protocol comparing intercostal tube drainage, pigtail catheter drainage, and ultrasound-guided aspiration for treating mass…
-
CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG [NA]
A clinical trial called ARMSTRONG is evaluating air entraintment versus standard treatment in non-expandable lung conditions and is currentl…
-
CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. [NA]
Clinical trial assessing first local anesthesia thoracoscopy for diagnosing pleural effusion in patients with suspected malignant lung disea…
-
CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion [Phase 1]
This document reports a Phase Ib study of JMKX000197 injection for malignant pleural effusion that is currently recruiting.
-
CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion [NA]
The University of Hong Kong-sponsored trial comparing different sizes of small-bore chest drains for malignant pleural effusion in stage IV …
-
CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: A Study of MT027 in Patients with Pleural Malignant Tumors [Phase 1]
Phase 1 clinical trial evaluating MT027 in patients with pleural malignant tumors, currently recruiting.
-
CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Pleural Carcinomatosis Tissue Banking
Enrollment is underway for a pleural tissue banking study focused on malignant pleural effusion. The update does not report results or effic…