Malignant Glioma
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Sign up freeTop drugs studied for this disease
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FDA approval · 2018-08-22FDA Approved: GLEOLAN — Supplemental Application (Medexus Pharma, Inc.)
FDA approved a supplemental application for Gleolan (aminolevulinic acid hydrochloride) submitted by Medexus Pharma, Inc. This action consti…
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas [Phase 1]
Phase 1 clinical trial update reporting completion of DNX-2401 (Delta-24-RGD-4C) for recurrent malignant gliomas.
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy
A clinical trial update indicates that the adherence monitoring system trial to manage myelosuppression in newly diagnosed malignant glioma …
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma [Phase 1]
Phase 1 trial investigating imatinib mesylate in malignant glioma included tumor tissue analyses to assess biological effects of the drug.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Fenretinide in Treating Patients With Recurrent Malignant Glioma [Phase 2]
Phase 2 clinical trial evaluating fenretinide for recurrent malignant glioma has been completed.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating irinotecan for progressive or recurrent malignant glioma has completed. The trial's status is listed as …
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma [Phase 1, Phase 2]
This update reports completion of a Phase 1/2 clinical trial evaluating Imatinib Mesylate in patients with recurrent malignant glioma or men…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Gene Therapy in Treating Patients With Recurrent Malignant Gliomas [Phase 1]
A Phase 1 gene therapy trial for patients with recurrent malignant gliomas has completed enrollment and a status update has been posted.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma [Phase 1]
This update describes a Phase 1 trial of gefitinib plus temozolomide in patients with malignant primary glioma.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: O(6)-Benzylguanine in Treating Patients With Malignant Glioma [Phase 1]
A Phase 1 clinical trial of O6-benzylguanine in patients with malignant glioma has completed, with an update on the study status.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma [Phase 1]
A phase 1 clinical trial evaluating the combination of temozolomide and irinotecan in patients with recurrent malignant glioma has completed…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: CCI-779 in Treating Patients With Malignant Glioma [Phase 1, Phase 2]
Completed Phase 1/2 trial evaluating CCI-779 (temsirolimus) in patients with malignant glioma.
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Tipifarnib in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
Clinical trial update reporting completion of a Phase 1/2 study of tipifarnib for malignant glioma.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas
A completed clinical trial evaluating rotating frame relaxation and diffusion-weighted imaging in patients with gliomas.
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FDA approval · 2018-06-12FDA Approved: GLEOLAN — Supplemental Application (Medexus Pharma, Inc.)
FDA approved a supplemental application for Gleolan (aminolevulinic acid hydrochloride) submitted by Medexus Pharma, Inc.
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery [Phase 1, Phase 2]
Phase 1/2 trial evaluating cetuximab-IRDye 800CW for intraoperative detection of tumors in malignant glioma patients undergoing surgery; stu…
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma [Phase 2]
Phase 2 trial evaluating bevacizumab, temozolomide, and hypofractionated radiotherapy in newly diagnosed malignant glioma; study status comp…
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiforme [Phase 2]
Phase II study of rindopepimut (CDX-110) in glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Thalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignant Glioma [Phase 2]
A Phase 2 trial evaluated thalidomide, celecoxib, and combination chemotherapy in patients with relapsed or refractory malignant glioma; the…
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FDA approval · 2017-06-06FDA Approved: GLEOLAN — Original Application (Medexus Pharma, Inc.)
The FDA approved Gleolan (aminolevulinic acid hydrochloride) from Medexus Pharma under NDA208630 for use in fluorescence-guided visualizatio…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma [NA]
A terminated clinical trial evaluating stem cell radiotherapy with temozolomide for newly diagnosed high-grade glioma has posted results.
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Bevacizumab in the Radiation Treatment of Recurrent Malignant Glioma [NA]
This Clinical Trial Update reports that a trial of Bevacizumab in combination with radiation therapy for recurrent malignant glioma has comp…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Vaccination-Dendritic Cells With Peptides for Recurrent Malignant Gliomas [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating vaccination with dendritic cells loaded with peptides for recurrent malignant glioma; completed with res…
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FDA approval · 2017-04-26FDA Approved: TEMOZOLOMIDE — Original Application (CivicaScript LLC)
FDA approved Temozolomide under CivicaScript LLC's original application (ANDA207658), marking the approval of a generic Temozolomide product…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Dendritic Cell Vaccine With Imiquimod for Patients With Malignant Glioma [Phase 1]
Phase 1 trial evaluating a dendritic cell vaccine with Imiquimod in malignant glioma has been completed. The study investigates safety and p…