Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: ONC201 in Pediatric H3 K27M Gliomas [Phase 1]
Phase 1 trial update of ONC201 in pediatric H3 K27M gliomas including Diffuse Intrinsic Pontine Glioma and malignant glioma has been termina…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: 18F-DOPA-PET in Planning Surgery in Patients With Gliomas [EARLY_Phase 1]
A Phase 1 clinical trial evaluating 18F-DOPA-PET imaging to aid surgical planning for malignant glioma and recurrent brain neoplasms has com…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Psychological Intervention For Brain Tumor Caregivers [NA]
A Massachusetts General Hospital trial evaluating a psychological intervention for caregivers of brain tumor patients has completed. The stu…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma [Phase 1]
Phase 1 trial evaluating neo-adjuvant glioma lysate vaccines in WHO Grade II glioma has completed.
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CLINICAL_TRIALS other · 2024-10-31Clinical Trial Update: Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma [Phase 1]
Phase 1 clinical trial is recruiting to evaluate safety and preliminary efficacy of TS-2021 for recurrent malignant glioma, including gliobl…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma [Phase 1]
Phase 1 trial evaluates genetically modified T-cells (CAR-T) in patients with recurrent or refractory malignant glioma. Results have been po…
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CLINICAL_TRIALS withdrawal · 2024-10-26Clinical Trial Update: Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer [Phase 1]
A Phase 1 trial investigating chemotherapy and donor stem cell transplantation for high-grade brain cancers has been withdrawn. The study in…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastoma [Phase 1]
A Phase 1 trial investigating dexamethasone and azeliragon for post-resection cerebral edema in glioblastoma patients has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Glioma [Phase 1, Phase 2]
Clinical trial update indicates a Phase 1/2 study of a novel oncolytic virus for recurrent malignant glioma (including glioblastoma) has bee…
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: In Vitro Models From Pediatric Brain Tumors
The update describes a study focused on developing in vitro models of pediatric brain tumors, including malignant glioma, ependymoma, and me…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma [Phase 2]
A Phase 2 clinical trial assessing the addition of plerixafor to standard temozolomide-based chemoradiotherapy for glioblastoma has complete…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating the pharmacodynamics and pharmacokinetics of evolocumab (a PCSK9 inhibitor) in patients with mali…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
A pediatric MATCH phase 2 trial assessed olaparib in children with relapsed or refractory advanced solid tumors or non-Hodgkin lymphoma carr…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with radiation therapy and temozolomide for newly diagnosed malignant glioma; res…
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma [Phase 2]
Phase 2a study of CAN-2409 with standard radiation therapy in malignant glioma (including glioblastoma multiforme) has completed; results po…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas [Phase 2]
Phase 2 trial evaluating hypofractionated stereotactic radiotherapy combined with anlotinib for recurrent high-grade gliomas.
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas [Phase 1]
A pediatric Phase 1 trial evaluating selinexor in children with recurrent or refractory solid tumors and high-grade gliomas has completed. R…
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CLINICAL_TRIALS trial_result · 2023-11-14Clinical Trial Update: 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy [Phase 2]
Phase 2 trial evaluating 18F-DOPA-PET/MRI imaging in elderly patients with newly diagnosed grade IV malignant glioma or glioblastoma during …
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas [Phase 1]
Phase 1 trial evaluating hypofractionated stereotactic irradiation with pembrolizumab and bevacizumab for recurrent high-grade gliomas has c…
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide [Phase 2]
Phase 2 trial assessing rolapitant as an antiemetic for chemo-radiation–induced nausea and vomiting in malignant glioma patients receiving r…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy [Phase 4]
Phase 4 trial assessing Perampanel for reducing seizure frequency in patients with high-grade glioma and focal epilepsy has been terminated …
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous CMV-specific cytotoxic T cells with temozolomide in glioblastoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-09-29Clinical Trial Update: Psychological Intervention for Caregivers of Patients With Malignant Gliomas [NA]
The clinical trial evaluating a psychological intervention for caregivers of patients with malignant gliomas has completed and posted result…