Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma [Phase 2]
Open-label Phase 2 trial evaluating OKN-007 in combination with temozolomide for recurrent glioblastoma has completed.
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas. [Phase 2]
Phase 2 clinical trial evaluating whether hydrogen-rich water improves quality of life in patients receiving radiotherapy for high-grade mal…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Imaging of Solid Tumors Using 18F-TRX [Phase 1]
A Phase 1 study is evaluating imaging of solid tumors with the radiotracer 18F-TRX. The trial is currently recruiting and includes prostate …
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Lerapolturev in Recurrent Malignant Glioma [Phase 2]
Phase 2 clinical trial results update for Lerapolturev in recurrent malignant glioma; the study has completed and results have been posted.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Fimepinostat in Treating Brain Tumors in Children and Young Adults [EARLY_Phase 1]
This is an early-phase 1 trial update on fimepinostat for pediatric and young adult brain tumors, including DIPG, recurrent anaplastic astro…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma [Phase 1]
Phase 1 clinical trial update for PEP-CMV in recurrent medulloblastoma and malignant glioma.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial [NA]
Clinical trial update for Proton Pulsed Reduced Dose Rate Radiotherapy (PPRDR) in recurrent CNS malignancies; the trial is currently recruit…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating the safety and tolerability of Fb-PMT in patients with recurrent glioblastoma, with recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas [Phase 1, Phase 2]
The study evaluates pembrolizumab in combination with MRI-guided laser ablation for recurrent malignant gliomas, with Phase 1/2 results post…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: 18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas [NA]
A clinical trial comparing 18F-FET-PET/MRI planning to standard MRI planning for stereotactic radiotherapy in patients with malignant glioma…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases [NA]
Clinical trial comparing intraoperative sonography to fluorescence-guided resection for contrast-enhancing gliomas and brain metastases has …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases [NA]
This clinical trial update reports a recruitment-status study (NCT05474573) evaluating fluorescence- and ultrasound-guided eradication of co…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4) [Phase 3]
A Phase III clinical trial is evaluating resection efficacy using fluorescence-guided surgery with 5-ALA HCl versus conventional white-light…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: D2C7-IT With Atezolizumab for Recurrent Gliomas [Phase 1]
Phase 1 clinical trial update of D2C7-IT in combination with atezolizumab for recurrent malignant glioma; study currently active but not rec…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma [Phase 1]
An update reports the completion of a Phase 1 pilot immunotherapy trial (Antisense102) for newly diagnosed malignant glioma. The study evalu…
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CLINICAL_TRIALS other · 2025-05-06Clinical Trial Update: Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma [Phase 1]
Phase 1 clinical trial update for D2C7-IT in combination with 2141-V11 in recurrent malignant glioma; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults [Phase 1]
Phase 1 clinical trial evaluating immunotherapy before and after surgery for recurrent or progressive high-grade glioma in children and youn…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Pilot Immunotherapy Trial for Recurrent Malignant Gliomas [Phase 1]
A Phase 1 pilot immunotherapy trial for recurrent malignant gliomas has completed (status COMPLETED).
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: 5G-EMERALD: Amivantamab in Malignant Brain Tumours [Phase 1]
A Phase 1 clinical trial of amivantamab for malignant brain tumors, including glioblastoma and related gliomas, is currently recruiting in t…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors [Phase 1]
Volitinib is being studied in a Phase 1 trial for patients with recurrent or refractory primary CNS tumors, with the study currently listed …
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) [Phase 1]
A Phase 1 clinical trial investigating a laparoscopically harvested omental autograft to bypass the blood-brain barrier in recurrent gliobla…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas
This clinical trial update outlines an integrated analysis of how embryonal tumors and gliomas respond to therapy and develop resistance, in…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma [Phase 1]
Phase 1 trial evaluating a neoepitope-specific cancer vaccine for progressive malignant glioma has completed. The update indicates the study…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Modulation of Ciliogenesis in Glioma Stem Cells [NA]
This clinical trial update reports on a study investigating modulation of ciliogenesis in glioma stem cells for glioblastoma and malignant g…