Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors [Phase 1]
Phase 1 trial evaluating ribociclib with everolimus in pediatric patients with recurrent or refractory malignant brain tumors; completed wit…
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma [Phase 1]
Phase 1 trial evaluating CMV RNA-pulsed dendritic cells in pediatric and young adult patients with recurrent malignant glioma and related br…
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CLINICAL_TRIALS trial_result · 2020-12-02Clinical Trial Update: Bevacizumab Beyond Progression (BBP) [Phase 2]
Phase 2 clinical trial update on Bevacizumab Beyond Progression in malignant glioma including glioblastoma and gliosarcoma; results posted a…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas [Phase 2]
Phase II trial of perifosine for recurrent/progressive malignant gliomas completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-09-03Clinical Trial Update: Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma [Phase 1, Phase 2]
Clinical trial update for ABT-414 in Japanese subjects with malignant glioma (phase 1/2) completed.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 study of Sym004 in adults with recurrent glioblastoma has completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: SarCNU in Treating Patients With Recurrent Malignant Glioma [Phase 2]
Phase 2 clinical trial update for SarCNU in patients with recurrent malignant glioma.
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy [Phase 2]
A Phase 2 study evaluating 18F-DOPA-PET imaging to locate tumors in patients with newly diagnosed malignant glioma undergoing radiation ther…
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: Nivolumab With DC Vaccines for Recurrent Brain Tumors [Phase 1]
Phase 1 trial evaluating nivolumab in combination with dendritic cell vaccines for recurrent brain tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: First in Patient Study for PF-06840003 in Malignant Gliomas [Phase 1]
Phase 1 trial update for PF-06840003 in malignant gliomas has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII [Phase 1, Phase 2]
Phase 1/2 trial of EGFRvIII-targeted CAR T cell therapy for malignant gliomas expressing EGFRvIII has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Lacosamide in Preventing Seizures in Participants With Malignant Glioma [NA]
Clinical trial update for lacosamide in preventing seizures in participants with malignant glioma; study terminated with results posted in 2…
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CLINICAL_TRIALS trial_result · 2018-09-28Clinical Trial Update: PVSRIPO for Recurrent Glioblastoma (GBM) [Phase 1]
Phase 1 clinical trial update for PVSRIPO in recurrent glioblastoma (GBM) completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas [Phase 1]
Phase 1 clinical trial update reporting completion of DNX-2401 (Delta-24-RGD-4C) for recurrent malignant gliomas.
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy
A clinical trial update indicates that the adherence monitoring system trial to manage myelosuppression in newly diagnosed malignant glioma …
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma [Phase 1]
Phase 1 trial investigating imatinib mesylate in malignant glioma included tumor tissue analyses to assess biological effects of the drug.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Fenretinide in Treating Patients With Recurrent Malignant Glioma [Phase 2]
Phase 2 clinical trial evaluating fenretinide for recurrent malignant glioma has been completed.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating irinotecan for progressive or recurrent malignant glioma has completed. The trial's status is listed as …
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma [Phase 1, Phase 2]
This update reports completion of a Phase 1/2 clinical trial evaluating Imatinib Mesylate in patients with recurrent malignant glioma or men…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Gene Therapy in Treating Patients With Recurrent Malignant Gliomas [Phase 1]
A Phase 1 gene therapy trial for patients with recurrent malignant gliomas has completed enrollment and a status update has been posted.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma [Phase 1]
This update describes a Phase 1 trial of gefitinib plus temozolomide in patients with malignant primary glioma.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: O(6)-Benzylguanine in Treating Patients With Malignant Glioma [Phase 1]
A Phase 1 clinical trial of O6-benzylguanine in patients with malignant glioma has completed, with an update on the study status.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma [Phase 1]
A phase 1 clinical trial evaluating the combination of temozolomide and irinotecan in patients with recurrent malignant glioma has completed…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: CCI-779 in Treating Patients With Malignant Glioma [Phase 1, Phase 2]
Completed Phase 1/2 trial evaluating CCI-779 (temsirolimus) in patients with malignant glioma.
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Tipifarnib in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
Clinical trial update reporting completion of a Phase 1/2 study of tipifarnib for malignant glioma.