Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma [Phase 1]
Phase 1 trial evaluates genetically modified T-cells (CAR-T) in patients with recurrent or refractory malignant glioma. Results have been po…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Glioma [Phase 1, Phase 2]
Clinical trial update indicates a Phase 1/2 study of a novel oncolytic virus for recurrent malignant glioma (including glioblastoma) has bee…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma [Phase 2]
A Phase 2 clinical trial assessing the addition of plerixafor to standard temozolomide-based chemoradiotherapy for glioblastoma has complete…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating the pharmacodynamics and pharmacokinetics of evolocumab (a PCSK9 inhibitor) in patients with mali…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
A pediatric MATCH phase 2 trial assessed olaparib in children with relapsed or refractory advanced solid tumors or non-Hodgkin lymphoma carr…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with radiation therapy and temozolomide for newly diagnosed malignant glioma; res…
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma [Phase 2]
Phase 2a study of CAN-2409 with standard radiation therapy in malignant glioma (including glioblastoma multiforme) has completed; results po…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas [Phase 2]
Phase 2 trial evaluating hypofractionated stereotactic radiotherapy combined with anlotinib for recurrent high-grade gliomas.
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas [Phase 1]
A pediatric Phase 1 trial evaluating selinexor in children with recurrent or refractory solid tumors and high-grade gliomas has completed. R…
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CLINICAL_TRIALS trial_result · 2023-11-14Clinical Trial Update: 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy [Phase 2]
Phase 2 trial evaluating 18F-DOPA-PET/MRI imaging in elderly patients with newly diagnosed grade IV malignant glioma or glioblastoma during …
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas [Phase 1]
Phase 1 trial evaluating hypofractionated stereotactic irradiation with pembrolizumab and bevacizumab for recurrent high-grade gliomas has c…
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide [Phase 2]
Phase 2 trial assessing rolapitant as an antiemetic for chemo-radiation–induced nausea and vomiting in malignant glioma patients receiving r…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy [Phase 4]
Phase 4 trial assessing Perampanel for reducing seizure frequency in patients with high-grade glioma and focal epilepsy has been terminated …
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous CMV-specific cytotoxic T cells with temozolomide in glioblastoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-09-29Clinical Trial Update: Psychological Intervention for Caregivers of Patients With Malignant Gliomas [NA]
The clinical trial evaluating a psychological intervention for caregivers of patients with malignant gliomas has completed and posted result…
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma [Phase 2]
Phase 2 trial update on TTFields combined with pulsed bevacizumab for recurrent glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2022-06-09Clinical Trial Update: Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases [NA]
Trial update for Ferumoxytol assessing its utility in improving MR imaging for high-grade brain tumors and cerebral metastases; study comple…
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CLINICAL_TRIALS trial_result · 2022-06-08Clinical Trial Update: Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab [Phase 1, Phase 2]
Phase 1/2 trial evaluating marizomib with bevacizumab, then marizomib alone, then marizomib with bevacizumab in malignant glioma/glioblastom…
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: Combination Chemotherapy With or Without Sodium Thiosulfate in Preventing Low Platelet Count While Treating Patients With Malignant Brain Tumors [Phase 2]
Phase 2 clinical trial evaluating chemotherapy with or without sodium thiosulfate to prevent low platelet counts in malignant glioma patient…
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CLINICAL_TRIALS trial_result · 2022-04-18Clinical Trial Update: Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma [Phase 2]
Phase 2 trial evaluating tremelimumab and durvalumab, alone or in combination, for recurrent malignant glioma including recurrent glioblasto…
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CLINICAL_TRIALS trial_result · 2022-03-09Clinical Trial Update: Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers [Phase 1]
Phase 1 trial assessing cabiralizumab with nivolumab in selected advanced cancers has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-12-09Clinical Trial Update: Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and Over [Phase 3]
Phase 3 trial evaluating the impact of surgery on treatment outcomes for supratentorial malignant gliomas in subjects aged 70 and over. Comp…
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma [Phase 2]
A Phase 2 trial evaluating a combination of sorafenib, valproic acid, and sildenafil in patients with recurrent high-grade glioma has comple…