Malaria
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Malaria Molecular Surveillance in Mozambique (Phase 2)
Phase 2 malaria molecular surveillance trial in Mozambique is currently recruiting.
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Evaluation of a Comprehensive School Health Programme in Zambia [NA]
Status update on an ongoing trial in Zambia evaluating a comprehensive school health programme targeting helminth infections, malaria and re…
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Proactive Community Case Management for Malaria in Zambia [NA]
PATH-sponsored clinical trial on proactive community case management for malaria in Zambia has completed.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Studies of a Candidate Aminoquinoline Antimalarial (AQ-13) [Phase 2]
Phase 2 trials of AQ-13, a candidate aminoquinoline antimalarial, have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Anti-malaria MAb in Malian Children [Phase 2]
Phase 2 clinical trial of an anti-malaria monoclonal antibody in Malian children has completed, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Efficacy of Only IV Artesunate Versus IV Artesunate Plus IV Quinine in the Treatment of Severe Malaria in Children: A Comparative Study [NA]
A completed comparative trial in children with severe malaria evaluates the efficacy of IV artesunate alone versus IV artesunate plus IV qui…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities [NA]
A completed clinical trial evaluating mass drug administration with dihydroartemisinin-piperaquine and a single low-dose primaquine to accel…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Evaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda [NA]
Clinical trial evaluating the protective efficacy of a spatial repellent to reduce malaria prevalence in Uganda is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: Evaluating ATSBs for Malaria Reduction in Kenya [NA]
This document reports the completion of a clinical trial evaluating Attractive Targeted Sugar Baits (ATSBs) for malaria reduction in Kenya.
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: Controlled Human Malaria Infection Transmission Model - Phase A [Phase 1, Phase 2]
This update reports that the Phase A controlled human malaria infection transmission model trial (Phase 1/2) led by the University of Oxford…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age [Phase 2]
Phase 2 trial results update for GSK's malaria vaccine candidate SB257049, evaluating efficacy, safety and immunogenicity with schedules inc…
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FDA approval · 2024-05-20FDA Approved: HYDROXYCHLOROQUINE SULFATE — Supplemental Application (Amneal Pharmaceuticals NY LLC)
FDA approved a supplemental application for hydroxychloroquine sulfate from Amneal Pharmaceuticals NY LLC.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP [Phase 1]
Phase 1 study reports safety, tolerability, and antimalarial activity of single doses of OZ439 and PQP in malaria; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia [Phase 4]
Phase 4 trial update evaluating the efficacy of artesunate-amodiaquine and artemether-lumefantrine for treating uncomplicated Plasmodium fal…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in Mali [Phase 1]
A Phase 1 study of the malaria transmission-blocking vaccine Pfs230D1-EPA/Matrix-M in adults in Mali has completed and results have been pos…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria [NA]
This completed trial update reports results of TESTsmART Aim 2 in Nigeria, evaluating malaria diagnostic testing and conditional subsidies i…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali [Phase 2]
Phase 2 trial in Mali evaluating the safety and efficacy of CIS43LS, an anti-malaria monoclonal antibody, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Chemoprophylactic Activity of M5717 in PfSPZ Challenge Model [Phase 1]
Phase 1 trial update evaluating the chemoprophylactic activity of M5717 against malaria using the PfSPZ Challenge model in healthy volunteer…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar [NA]
This clinical trial update describes the efficacy of focal primaquine mass administration to eliminate Plasmodium vivax malaria in northern …
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays
This clinical investigation assesses the consistency and reproducibility of two consecutive mosquito feeding assays in malaria research; res…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar [NA]
This entry notes the completion of a clinical trial in rural Myanmar evaluating health education delivered by Buddhist monks to improve mala…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities [Phase 3]
Phase 3 trial update on innovative tools for vector-borne disease control in conflict-affected communities; study completed.
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: VAC071: A Study to Assess Efficacy of the ChAd63/MVA PvDBP Vaccines [Phase 2]
Phase 2 trial investigating the ChAd63/MVA PvDBP vaccines for Plasmodium vivax malaria has completed with results posted in 2024.
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FDA approval · 2024-04-02FDA Approved: ATOVAQUONE — Supplemental Application (Camber Pharmaceuticals, Inc.)
The FDA approved Camber Pharmaceuticals' supplemental application for atovaquone.
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique [Phase 4]
Phase 4 trial update on seasonal malaria chemoprevention in Mozambique under Malaria Consortium.