Malaria
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) [Phase 4]
Phase 4 trial update on enhancing preventive therapy for malaria in children with sickle cell anemia in East Africa; results have been poste…
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan [Phase 3]
Phase 3 clinical trial evaluating the effectiveness, feasibility, and acceptability of seasonal malaria chemoprevention in Aweil South Count…
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: Intermittent Preventive Treatment of Malaria in Schoolchildren [Phase 3]
A Phase 3 clinical trial updates on intermittent preventive treatment of malaria in schoolchildren; results have been posted following compl…
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Childbearing Potential in Mali [Phase 2]
Phase 2 trial assessing safety, immunogenicity, and protective efficacy of radiation-attenuated PfSPZ vaccine during malaria transmission se…
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate [Phase 2]
A Phase 2 study comparing a 1-step injectable artesunate with the conventional 2-step injectable artesunate in severe malaria has completed.
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Aggressive Antipyretics for Fever Reduction in CNS Malaria [Phase 2]
Phase 2 trial update on aggressive antipyretics for fever reduction in cerebral malaria with seizures; results completed and posted in 2024.
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CLINICAL_TRIALS research · 2024-02-23Clinical Trial Update: Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso [Phase 3]
A Phase 3 trial investigating malaria as a risk factor for COVID-19 in Western Kenya and Burkina Faso has completed.
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CLINICAL_TRIALS research · 2024-02-20Clinical Trial Update: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya [NA]
Clinical trial update on malaria diagnostic testing and subsidies to improve ACT access in Kenya; study completed with results posted in 202…
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: PfSPZ Vaccine Trial in Malian Children [Phase 2]
Phase 2 clinical trial update for PfSPZ Vaccine in Malian children with malaria, completed with results posted in 2024.
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FDA approval · 2024-02-02FDA Approved: CHLOROQUINE PHOSPHATE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
FDA approved a supplemental application for CHLOROQUINE PHOSPHATE from Amneal Pharmaceuticals of New York LLC. This action approves changes …
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CLINICAL_TRIALS research · 2024-02-02Clinical Trial Update: Malaria Therapeutic Efficacy Study, Rwanda [Phase 4]
Phase 4 clinical trial update on malaria treatment efficacy in Rwanda has completed.
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FDA approval · 2024-01-24FDA Approved: HYDROXYCHLOROQUINE SULFATE — Supplemental Application (Ipca Laboratories Limited)
FDA approved a supplemental application for hydroxychloroquine sulfate manufactured by Ipca Laboratories Limited. The approval updates the p…
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Repeat Ivermectin Mass Drug Administrations for MALaria Control II [Phase 3]
Phase 3 clinical trial results have been posted for repeat ivermectin mass drug administrations to help control malaria. The study is comple…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers [Phase 1]
Phase 1 trial reporting relative bioavailability of pyronaridine-artesunate tablet versus granule formulations in healthy volunteers.
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate [Phase 1]
Phase 1 clinical trial update examining drug interaction between pyronaridine-artesunate and metoprolol, plus redosing study of pyronaridine…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax Malaria [Phase 2]
Phase 2 trial assessing the efficacy of SJ733 in adults with uncomplicated Plasmodium falciparum or vivax malaria has completed with results…
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FDA approval · 2023-11-29FDA Approved: HYDROXYCHLOROQUINE SULFATE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approved a supplemental application for HYDROXYCHLOROQUINE SULFATE from Dr. Reddy's Laboratories Inc.
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso [Phase 3]
Phase 3 clinical trial update exploring intermittent preventive treatment strategies to reduce malaria burden in school-age children in Burk…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas [Phase 4]
Phase 4 clinical trial evaluating strategies to reduce risk of Plasmodium vivax after Plasmodium falciparum infections in co-endemic areas, …
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: Effectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementation Study [Phase 4]
Phase 4 hybrid implementation study evaluating the effectiveness of seasonal malaria chemoprevention in Nampula Province, Mozambique.
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Chemoprevention Efficacy Study in Burkina Faso [Phase 4]
Phase 4 clinical trial update assessing chemoprevention efficacy for malaria in Burkina Faso.
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Effectiveness and Chemoprevention Efficacy of Implementing Seasonal Malaria Chemoprevention in Karamoja Region, Uganda [Phase 4]
Phase 4 trial update evaluating effectiveness and chemoprevention efficacy of seasonal malaria chemoprevention in Karamoja, Uganda.
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CLINICAL_TRIALS trial_result · 2023-10-16Clinical Trial Update: First-in-Human Trial of Single Ascending Dose, Multiple Ascending Dose and Malaria Challenge Model in Healthy Participants [Phase 1]
Phase 1 first-in-human trial evaluating single ascending dose, multiple ascending dose, and a malaria challenge model in healthy participant…
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CLINICAL_TRIALS trial_result · 2023-10-13Clinical Trial Update: Trial to Evaluate L9LS in Healthy Adults [Phase 1]
Phase 1 trial evaluating the monoclonal antibody L9LS in healthy adults to assess safety and pharmacokinetics for malaria. The study has com…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Early Childhood Malaria Prevention With Maloprim in The Gambia [Phase 4]
Phase 4 clinical trial assessing early childhood malaria prevention with Maloprim in The Gambia has completed.