Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS safety_alert · 2012-04-27Clinical Trial Update: Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function [Phase 4]
Phase 4 safety update examining whether artemether-lumefantrine and other malaria drugs affect auditory function.
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CLINICAL_TRIALS trial_result · 2012-04-26Clinical Trial Update: Trial of Malaria Seasonal IPTc Combined With Community Case Management [Phase 3]
Phase 3 trial evaluating seasonal intermittent preventive treatment in children (IPTc) with community case management for malaria has comple…
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CLINICAL_TRIALS trial_result · 2012-04-24Clinical Trial Update: Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers [Phase 1]
The Phase 1 trial evaluated safety and pharmacokinetics of a low-dose methotrexate in healthy Kenyan adult male volunteers and is completed.
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CLINICAL_TRIALS trial_result · 2012-04-19Clinical Trial Update: Intermittent Parasite Clearance (IPC) in Schools: Impact on Malaria, Anaemia and Cognition [NA]
Completed trial evaluating intermittent parasite clearance in schoolchildren and its impact on malaria, anemia, and cognitive outcomes.
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CLINICAL_TRIALS trial_result · 2012-04-18Clinical Trial Update: Effect of Blood Storage Age on the Resolution of Lactic Acidosis in Children With Severe Malarial Anemia at Mulago Hospital [NA]
This completed trial from Makerere University evaluated whether the storage age of donor packed red blood cells affects the resolution of la…
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CLINICAL_TRIALS trial_result · 2012-04-13Clinical Trial Update: Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in Brazil [Phase 4]
A Phase 4 trial assessing artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria in pregnant individuals in…
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CLINICAL_TRIALS withdrawal · 2012-04-13Clinical Trial Update: Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum Infection [Phase 2, Phase 3]
Clinical trial investigating the pharmacokinetics of the mefloquine-artesunate combination in pregnant women with uncomplicated Plasmodium f…
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CLINICAL_TRIALS research · 2012-03-28Clinical Trial Update: Parasite-based Diagnosis for Malaria in Uganda: Feasibility and Cost-Effectiveness [NA]
This update reports on a Uganda-based clinical trial assessing the feasibility and cost-effectiveness of parasite-based malaria diagnosis.
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CLINICAL_TRIALS trial_result · 2012-03-23Clinical Trial Update: Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra [Phase 4]
Phase 4 clinical trial evaluating whether adding primaquine to dihydroartemisinin-piperaquine reduces malaria transmission in Lampung Provin…
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs [NA]
A clinical trial update indicates the study evaluating rapid diagnostic testing in home management with ACTs for malaria and pneumonia has c…
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CLINICAL_TRIALS trial_result · 2012-03-13Clinical Trial Update: Study of the Environmental Factors Modulating Children Immune Response in Northern Senegal
The trial evaluating environmental factors affecting immune responses in children in Northern Senegal has completed, sponsored by the Biomed…
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EMA guidance · 2012-02-17European Medicines Agency recommends new anti-malaria treatment for use outside the European Union
EMA recommends a new anti-malaria treatment for use outside the European Union, expanding access internationally.
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: Treatment of Non-falciparum Malaria [NA]
This clinical trial update notes that a study on the treatment of acute non-falciparum malaria has completed.
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CLINICAL_TRIALS trial_result · 2011-11-15Clinical Trial Update: Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar
A completed clinical trial evaluating the effectiveness of rapid diagnostic tests for malaria in Zanzibar's low-endemic setting.
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CLINICAL_TRIALS trial_result · 2011-11-11Clinical Trial Update: Congenital and Neonatal Malaria in Mali
A completed clinical trial in Mali on congenital and neonatal malaria.
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CLINICAL_TRIALS trial_result · 2011-11-10Clinical Trial Update: Worm Infestation and Child Health in Zimbabwe
A completed University of Zimbabwe trial evaluated integrated control of malaria and polyparasitism to improve child health in Zimbabwe.
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CLINICAL_TRIALS trial_result · 2011-11-03Clinical Trial Update: Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children [Phase 2]
This Phase 2 trial evaluating fosmidomycin in combination with clindamycin for acute uncomplicated Plasmodium falciparum malaria in children…
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CLINICAL_TRIALS research · 2011-11-03Clinical Trial Update: Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults [Phase 2]
Phase 2 clinical trial evaluating fosmidomycin in combination with azithromycin for acute uncomplicated Plasmodium falciparum malaria in adu…
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CLINICAL_TRIALS trial_result · 2011-10-28Clinical Trial Update: Age of Exposure and Immunity to Malaria in Infants [NA]
A completed clinical trial study from Hospital Clinic of Barcelona examined how age of exposure affects immunity to malaria in infants.
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CLINICAL_TRIALS research · 2011-10-25Clinical Trial Update: Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana [Phase 4]
A Phase 4 clinical trial update on ACT-IPT in schoolchildren in Kassena-Nankana, Ghana. The study assesses intermittent preventive treatment…
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CLINICAL_TRIALS trial_result · 2011-10-21Clinical Trial Update: Insecticide Treated Polyethylene Sheeting for Prevention of Malaria in Emergencies [Phase 3]
A Phase 3 trial evaluating insecticide-treated polyethylene sheeting for malaria prevention in emergency settings has completed.
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CLINICAL_TRIALS withdrawal · 2011-09-27Clinical Trial Update: Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate [Phase 2]
A Phase 2 trial evaluating fosmidomycin with clindamycin, with or without artesunate, for malaria has been withdrawn.
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FDA approval · 2011-09-20FDA Approved: MEFLOQUINE HYDROCHLORIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for mefloquine hydrochloride from Teva Pharmaceuticals USA, Inc., likely authorizing changes to labe…
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CLINICAL_TRIALS trial_result · 2011-09-19Clinical Trial Update: Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc) [Phase 1, Phase 2]
This update reports pharmacokinetic results from Phase 1/2 studies of sulfadoxine-pyrimethamine plus amodiaquine used for intermittent preve…
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CLINICAL_TRIALS trial_result · 2011-09-16Clinical Trial Update: Phase II Artesunate Study in Severe Malaria [Phase 2]
Phase II trial evaluating artesunate for severe malaria has completed.