Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-11-29Clinical Trial Update: A Study to Assess the Effectiveness of a New Malaria Vaccine Candidate by Infecting Vaccinated Volunteers With Malaria Parasites [Phase 1, Phase 2]
A Phase 1/2 clinical trial at the University of Oxford evaluating a new malaria vaccine candidate by deliberately infecting vaccinated volun…
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CLINICAL_TRIALS trial_result · 2012-11-29Clinical Trial Update: Safety and Immunogenicity of New Malaria Vaccine Candidate ChAd63 CS Administered Alone and With MVA CS [Phase 1]
Phase 1 study assessing safety and immunogenicity of the malaria vaccine candidate ChAd63 CS administered alone or with MVA CS; early immuno…
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CLINICAL_TRIALS trial_result · 2012-11-27Clinical Trial Update: Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria Infection [NA]
A completed clinical trial comparing three Plasmodium falciparum isolates in a controlled human malaria infection to assess differences in i…
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CLINICAL_TRIALS trial_result · 2012-11-27Clinical Trial Update: Reducing the Burden of Malaria by Targeting Hotspots of Malaria Transmission [NA]
The document reports a completed clinical trial aimed at reducing malaria transmission by targeting hotspots of transmission.
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: Impact of Insecticide Resistance on Vector Control [Phase 4]
This Phase 4 clinical trial update examines how insecticide resistance impacts vector control strategies for malaria.
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CLINICAL_TRIALS trial_result · 2012-10-22Clinical Trial Update: Hyperphenylalaninemia in Cerebral Malaria
A University of Utah–sponsored study investigating hyperphenylalaninemia in cerebral malaria (associated with Plasmodium falciparum malaria)…
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CLINICAL_TRIALS trial_result · 2012-10-12Clinical Trial Update: Introducing Rapid Diagnostic Tests Into the Private Health Sector [NA]
This update reports a completed clinical trial evaluating the introduction of rapid diagnostic tests into the private health sector for feve…
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CLINICAL_TRIALS trial_result · 2012-10-12Clinical Trial Update: Role and Effectiveness of Rapid Diagnostic Tests in Home-based Management of Malaria [NA]
A completed trial evaluated the role and effectiveness of rapid diagnostic tests in home-based management of malaria. The sponsor was DBL - …
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CLINICAL_TRIALS trial_result · 2012-10-03Clinical Trial Update: Safety and Immunogenicity of AdCh63 ME-TRAP and MVA ME-TRAP Vaccines in Malaria Endemic Areas [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of AdCh63 ME-TRAP and MVA ME-TRAP malaria vaccines in malaria-endemic areas has compl…
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CLINICAL_TRIALS research · 2012-10-03Clinical Trial Update: Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali [Phase 1]
Phase 1b malaria trial investigating Argemone mexicana in healthy adults in Mali; the update provides no results.
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CLINICAL_TRIALS trial_result · 2012-10-03Clinical Trial Update: The Combined Use of Indoor Residual Spraying (IRS) and Long-lasting Insecticidal Nets (LLINs) for Malaria Prevention [Phase 4]
This Phase 4 clinical trial update examines the combined use of indoor residual spraying and long-lasting insecticidal nets for malaria prev…
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FDA approval · 2012-09-28FDA Approved: QUININE SULFATE — Original Application (Teva Pharmaceuticals USA, Inc.)
FDA approved the Original Application for Quinine Sulfate from Teva Pharmaceuticals USA, Inc., marking the approval of a generic antimalaria…
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya [Phase 4]
A Phase 4 trial in pregnant women in Western Kenya evaluated whether folic acid affects the efficacy of sulfadoxine-pyrimethamine against ma…
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: Intermittent Preventive Treatment With Antimalarials in Kenyan Infants [NA]
This entry notes that a trial of intermittent preventive treatment with antimalarials in Kenyan infants is completed; no results are provide…
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria [Phase 4]
This Phase 4 trial evaluated the efficacy of a sulfadoxine-pyrimethamine and artemisinin-containing combination therapy for uncomplicated ma…
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy [Phase 4]
Phase 4 trial evaluated the efficacy of a combination therapy to prevent malaria-related effects during pregnancy and has completed.
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines [NA]
Clinical trial completed comparing chloroquine plus sulfadoxine-pyrimethamine against artemether plus lumefantrine for uncomplicated Plasmod…
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CLINICAL_TRIALS trial_result · 2012-09-07Clinical Trial Update: A Study to Assess the Immunogenicity, Tolerability and Safety of a Malaria Vaccine and Also Its Protective Efficacy in a Malaria Challenge Model [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of a malaria vaccine, assessing immunogenicity, tolerability, safety, and …
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CLINICAL_TRIALS trial_result · 2012-08-22Clinical Trial Update: Evaluation of SP Resistance and Effectiveness of IPTp in Nigeria [Phase 4]
A Phase 4 clinical trial update from Malaria Consortium evaluating resistance to sulfadoxine-pyrimethamine and the effectiveness of intermit…
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CLINICAL_TRIALS trial_result · 2012-08-22Clinical Trial Update: A Study of AdCh63 ME-TRAP Alone and With MVA ME-TRAP [Phase 1]
Phase 1 study of AdCh63 ME-TRAP alone and in combination with MVA ME-TRAP for malaria has completed.
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CLINICAL_TRIALS trial_result · 2012-08-16Clinical Trial Update: Artemether-Lumefantrine Clinical Effectiveness Study [Phase 4]
Phase 4 clinical trial assessing the effectiveness of artemether-lumefantrine for malaria, sponsored by the Papua New Guinea Institute of Me…
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FDA label_change · 2012-08-06FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for COARTEM (artemether-lumefantrine) from Novartis. This action updates the labeling and/or exp…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Feasibility and Impact of Malaria Rapid Diagnostic Tests in the African Retail Sector [NA]
A completed clinical trial assessing the feasibility and impact of malaria rapid diagnostic tests in the African retail sector.
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CLINICAL_TRIALS trial_result · 2012-05-31Clinical Trial Update: Antioxidant Micronutrients in Malaria [Phase 3]
This update reports on a Phase 3 trial evaluating antioxidant micronutrients for malaria, with the study status listed as completed.
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CLINICAL_TRIALS research · 2012-05-25Clinical Trial Update: Trial for Malaria Vaccine Candidate, PfPEBS (P. Falciparum Pre-Erythrocytic and Blood Stage) [Phase 1, Phase 2]
Clinical trial update for the PfPEBS malaria vaccine candidate from Vac4All, spanning Phase 1 and Phase 2; current status is unknown.