Malaria
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART [EARLY_Phase 1]
This early-phase trial update compares malaria infection levels in HIV-infected infants and children on protease inhibitor–based HAART versu…
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CLINICAL_TRIALS trial_result · 2016-09-16Clinical Trial Update: Frequency and Distribution of Mixed Falciparum-vivax Infections in French Guiana
Completed clinical trial update reporting on the frequency and distribution of mixed Plasmodium falciparum–Plasmodium vivax infections in Fr…
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CLINICAL_TRIALS research · 2016-09-16Clinical Trial Update: Prevalence of Malaria Parasites in People Working in Illegal Gold Mining in French Guiana
A completed clinical trial assessing the prevalence of malaria parasites among people working in illegal gold mining in French Guiana. The s…
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Accelerating the Reduction of Malaria Transmission in Kanel, Ranérou and Linguère Districts [Phase 4]
A Phase 4 clinical trial sponsored by PATH evaluating strategies to reduce malaria transmission in Kanel, Ranérou and Linguère districts has…
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Evaluation of Seasonal Malaria Chemoprevention in Kita
A completed clinical trial in Kita evaluating Seasonal Malaria Chemoprevention (SMC), sponsored by the University of Bamako.
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia [Phase 2, Phase 3]
Phase 2/3 trial evaluating the safety of combining primaquine with dihydroartemisinin-piperaquine in G6PD-deficient males; the study was ter…
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CLINICAL_TRIALS research · 2016-09-09Clinical Trial Update: Research on the Economics of Artemisinin Combination Therapy (ACTs) for the Treatment of Malaria [NA]
A completed clinical trial evaluating the economics of artemisinin-based combination therapies for malaria treatment.
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Field Evaluation of Plant-based Mosquito Control [Phase 2]
Phase 2 field trial evaluating a plant-based mosquito control product has been completed, assessing its impact on malaria and arboviral infe…
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Bacillus Calmette-Guerin (BCG) Vaccine and Morbidity From Malaria [Phase 3]
A Phase 3 clinical trial evaluating whether the BCG vaccine affects malaria morbidity has completed.
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CLINICAL_TRIALS research · 2016-08-31Clinical Trial Update: A Comparison of Diagnostic Approaches for Malaria and Pneumonia
This document describes a clinical trial comparing diagnostic approaches for malaria and pneumonia; the current status of the study is unkno…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children [Phase 3]
Phase 3 trial assessing whether vitamin A with zinc and multivitamin supplementation reduces malaria morbidity in Ghanaian children; the stu…
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CLINICAL_TRIALS research · 2016-08-15Clinical Trial Update: Integrated Community Case Management Study in Eastern Province, Zambia [NA]
Clinical trial update on an integrated community case management study conducted in Eastern Province, Zambia, investigating malaria, diarrhe…
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects [Phase 1]
Phase 1 trial evaluating ACT-451840 for early blood-stage Plasmodium falciparum infection in healthy subjects completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-08-08Clinical Trial Update: Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum [NA]
A completed clinical trial evaluating how host iron status and iron supplementation influence the erythrocytic stage of Plasmodium falciparu…
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FDA approval · 2016-07-27FDA Approved: PRIMAQUINE PHOSPHATE — Supplemental Application (Sanofi-Aventis U.S. LLC)
The FDA approved a supplemental application for primaquine phosphate filed by Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Malaria Prevention Cambodia [NA]
A clinical trial in Cambodia studying malaria prevention has terminated; the update provides no results.
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FDA approval · 2016-06-23FDA Approved: PRIMAQUINE PHOSPHATE — Original Application (Ingenus Pharmaceuticals, LLC)
The FDA approved Ingenus Pharmaceuticals’ original application for primaquine phosphate, a generic antimalarial, to bring this product to ma…
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CLINICAL_TRIALS research · 2016-06-16Clinical Trial Update: Partnership and Dignity: a Mixed-methods Survey on Supporting and Retaining Uganda's Village Health Teams
A completed mixed-methods study from George Washington University evaluating how to support and retain Uganda's Village Health Teams, with i…
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar
This clinical trial update reports completion of a molecular surveillance study of artemisinin resistance in Plasmodium falciparum malaria i…
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FDA approval · 2016-06-01FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for COARTEM (artemether and lumefantrine) from Novartis Pharmaceuticals Corporation. The action expa…
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA) [Phase 1]
Phase 1 study (CHMI-SIKA) assessing controlled human malaria infection in semi-immune Kenyan adults; the trial status is currently unknown.
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: Novel mHealth Platform to Ensure Quality of Community-based Malaria Diagnosis [NA]
This entry reports the completion of a clinical trial evaluating a mobile health platform designed to improve the quality of community-based…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria [NA]
This completed clinical trial assesses the impact of widescale sulfadoxine-pyrimethamine use on newborn outcomes in Nigeria, focusing on mal…
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: Malaria Survey in the Tak Province Refugee Camps [NA]
This trial update notes the completion of a malaria survey conducted in refugee camps in Tak Province, sponsored by the University of Oxford…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults [Phase 1]
Phase 1 dose-escalation, randomized trial assessing safety, immunogenicity and efficacy of the PfSPZ Vaccine in Tanzanian adults; the study …