Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children [Phase 3]
A Phase 3 trial evaluating four regimens for malaria prevention in Senegalese children has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: A New Approach to Deliver Malaria Preventions to Pregnant Women at a Community Level in Uganda [NA]
This completed clinical trial evaluated a community-based approach to delivering malaria prevention to pregnant women in Uganda, focusing on…
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: Navrongo Drug Options for IPT in Pregnancy Trial [Phase 2, Phase 3]
Clinical trial update noting the completion of the Navrongo IPT in Pregnancy trial (Phase 2/Phase 3) evaluating drug options to prevent mala…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: A Trial of Improved Financial Access to Healthcare in Ghana [Phase 4]
Phase 4 clinical trial in Ghana evaluating improved financial access to healthcare for malaria; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Phase 2 Efficacy Study of Primaquine and Methylene Blue [Phase 2]
Phase 2 efficacy trial evaluating the combination of primaquine and methylene blue for malaria has completed.
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CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: School-based Programme of Malaria Diagnosis and Treatment in Southern Malawi [NA]
Completed clinical trial evaluating a school-based program for malaria diagnosis and treatment in southern Malawi.
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CLINICAL_TRIALS trial_result · 2016-12-09Clinical Trial Update: Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenya [Phase 3]
Phase 3 trial evaluating community-based mass screening and treatment for falciparum malaria in Western Kenya has completed.
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria [Phase 3]
A Phase 3 trial comparing Chlorproguanil-Dapsone-Artesunate (CDA) to Chlorproguanil-Dapsone (LAPDAP) for uncomplicated falciparum malaria ha…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa [Phase 3]
Phase 3 clinical trial evaluating susceptibility testing of antimalarial drugs to improve management of drug-resistant malaria in Sub-Sahara…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection [Phase 2]
Phase 2 study evaluating KAE609 (cipargamin) for Plasmodium falciparum malaria in adult males has completed and posted results.
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) [NA]
A completed study (NIDIAG-Fever) evaluated rapid diagnostic tests and clinical/laboratory predictors to diagnose tropical diseases in patien…
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Study of the Safety of Intravenous Artesunate [Phase 1]
A Phase 1 trial evaluated the safety of intravenous artesunate for malaria and has completed.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women [NA]
A completed clinical trial assessing the pharmacokinetics, efficacy, gametocyte carriage, and birth outcomes of intermittent presumptive tre…
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Artesunate Plus Sulfadoxine-pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria [NA]
A terminated clinical trial update evaluating artesunate plus sulfadoxine-pyrimethamine in pregnant women with malaria, examining pharmacoki…
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CLINICAL_TRIALS research · 2016-10-26Clinical Trial Update: Genetic Association Mapping of Malaria Resistance in Anopheles Gambiae
This clinical trial update reports genetic association mapping studies investigating malaria resistance in the Anopheles gambiae mosquito, e…
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: Azithromycin + Artesunate v Artemether-lumefantrine in Uncomplicated Malaria. [Phase 3]
Phase 3 trial comparing Azithromycin + Artesunate against Artemether-lumefantrine for uncomplicated malaria has completed.
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy [Phase 3]
This update notes the completion of a Phase 3 trial comparing Intermittent Preventive Treatment in pregnancy (IPTp) to approaches using Rapi…
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FDA label_change · 2016-10-11FDA Approved: MEFLOQUINE HYDROCHLORIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA approved a supplemental application for mefloquine hydrochloride (Teva), indicating changes to the product labeling.
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FDA approval · 2016-10-11FDA Approved: MEFLOQUINE HYDROCHLORIDE — Supplemental Application (Chartwell RX, LLC)
The FDA approved a supplemental application for generic mefloquine hydrochloride from Chartwell RX, LLC.
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CLINICAL_TRIALS withdrawal · 2016-10-06Clinical Trial Update: Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM) [NA]
A malaria-focused clinical trial in Zambia evaluating spatial repellent products has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-10-06Clinical Trial Update: Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Kenya [NA]
A clinical trial evaluating spatial repellent products for malaria prevention in Kenya has been withdrawn from the registry.
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CLINICAL_TRIALS withdrawal · 2016-10-06Clinical Trial Update: Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Tanzania [NA]
A clinical trial evaluating spatial repellent products for malaria control in Tanzania has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-10-05Clinical Trial Update: Dolutegravir Interactions With Artemisinin-based Combination Therapies [Phase 1]
Phase 1 trial completed examining potential interactions between dolutegravir and artemisinin-based combination therapies in malaria and HIV…
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Community-based Screening and Treatment of Malaria in Pregnancy: a Cluster-randomized Trial [NA]
This document reports the completion of a cluster-randomized trial evaluating community-based screening and treatment of malaria in pregnanc…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: A Study to Evaluate the Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Malaria Vaccine RTS,S/AS02A, When Administered to Children Aged 1 to 4 Years Living in a Malaria-endemic Region of Mozambique. [Phase 2]
Phase 2 trial of GlaxoSmithKline's RTS,S/AS02A malaria vaccine in children aged 1 to 4 years in Mozambique completed. The study assessed saf…