Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria [Phase 2]
Phase 2 clinical trial evaluating oral activated charcoal to assess its impact on the effectiveness of an antimalarial drug in Malian childr…
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CLINICAL_TRIALS trial_result · 2018-02-01Clinical Trial Update: Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi [Phase 3]
Phase 3 clinical trial update evaluating delivery of malaria chemoprevention in post-discharge management of children with severe anaemia in…
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot [Phase 4]
Phase 4 trial update comparing lumefantrine concentrations in venous plasma versus dried capillary blood spots for malaria.
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FDA label_change · 2018-01-08FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for COARTEM (artemether and lumefantrine) submitted by Novartis Pharmaceuticals Corporation. The app…
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of artemisinin-based combination treatments for malaria conducted in the De…
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure [Phase 4]
Phase 4 clinical trial comparing artemether/lumefantrine vs dihydroartemisinin-piperaquine for uncomplicated malaria and evaluating parasite…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi [NA]
This completed trial evaluated whether sending text message reminders to health workers improves case management for malaria, pneumonia, and…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients [Phase 1]
Phase 1 clinical trial comparing mefloquine with sulfadoxine-pyrimethamine as malaria prophylaxis in pregnant HIV-positive patients has comp…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients [Phase 1]
Phase 1 clinical trial comparing azithromycin and sulfadoxine-pyrimethamine as malaria prophylaxis in HIV-positive pregnant women has comple…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women [Phase 3]
Phase 3 trial evaluating protease inhibitors to reduce malaria morbidity in HIV-infected pregnant women has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria [Phase 3]
Phase 3 study evaluating the efficacy and safety of pyronaridine-artesunate and artemether-lumefantrine in paediatric malaria; trial complet…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults [Phase 1]
Phase 1 trial evaluating safety and immunogenicity of the Plasmodium falciparum vaccine candidate FMP012 with AS01B in healthy malaria-naïve…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil [NA]
A clinical trial evaluating artemether-lumefantrine for treating Plasmodium falciparum malaria in Brazil has completed, with results posted …
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CLINICAL_TRIALS withdrawal · 2017-08-29Clinical Trial Update: Leiden University Medical Center Mini Donor Bank
Leiden University Medical Center's Mini Donor Bank trial (NCT02810613) has been withdrawn; the listed conditions include malaria, Schistosom…
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CLINICAL_TRIALS research · 2017-08-25Clinical Trial Update: Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method [NA]
A completed clinical trial update from Wageningen University assessing model parameters for applying the Retinol Isotope Dilution method, wi…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh [Phase 4]
Phase 4 clinical trial assessing safety of current standard malaria treatment and G6PD status in Southeast Bangladesh; study completed with …
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in Children [Phase 3]
A Phase 3 trial update reports consistency of immunogenicity and non-inferiority for GlaxoSmithKline's malaria vaccine lots in children.
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria [Phase 1]
A first-in-human Phase 1 study in healthy volunteers to investigate a new medicine for malaria conducted by GlaxoSmithKline has been termina…
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CLINICAL_TRIALS trial_result · 2017-07-31Clinical Trial Update: Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, Mali [Phase 1]
A Phase 1 safety study of the malaria vaccine FMP1/AS02A in healthy adults in Mali has been completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, Mali [Phase 1]
Phase 1 trial update for the malaria vaccine FMP2.1/AS02A in malaria-experienced adults in Mali; the study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region
This completed clinical trial assessed using Sysmex technology to differentiate malaria from bacterial infections in a malaria-endemic regio…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313 [Phase 1]
An update on a Phase 1 trial evaluating the safety and immunogenicity of two malaria vaccine candidates, ChAd63 Pfs25-IMX313 and MVA Pfs25-I…
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CLINICAL_TRIALS trial_result · 2017-07-14Clinical Trial Update: Impact Evaluation of Community-Based Health Programs in Rwanda [NA]
A completed clinical trial in Rwanda evaluated community-based health programs addressing diarrhea and malaria.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Phase 1 Study of the Safety, Reactogenicity, and Immunogenicity of AMA1-C1/ISA 720: Blood Stage Vaccine for Plasmodium Falciparum [Phase 1]
Phase 1 study evaluating safety, reactogenicity, and immunogenicity of the AMA1-C1/ISA 720 blood-stage malaria vaccine; study completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Malaria Vaccine in Children in Mali [Phase 1, Phase 2]
The document reports the completion of Phase 1 and Phase 2 clinical trials of a malaria vaccine studied in children in Mali.