Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Evaluating Conversational Artificial Intelligence for Depression Management [NA]
George Mason University is evaluating a conversational AI system for depression management in a clinical trial that is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE [NA]
This NOT_YET_RECRUITING clinical trial is testing a collaborative care intervention for cancer patients and their family caregivers (LITE).
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression [NA]
Clinical trial update notes the study evaluating magnesium supplementation in combination with fluoxetine for cognitive function in adults w…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Retrospective Analyses of TrakStar Database
A clinical trial update describing retrospective analyses of the TrakStar database in depression and obsessive-compulsive disorder, with Neu…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial named RISE for Black Pregnant Women, sponsored by Cedars-Sinai, studying pregnancy-related mental health (dep…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pharmacogenetic-Guided Antidepressant Treatment in Depression [NA]
A clinical trial update for pharmacogenetic-guided antidepressant treatment in major depressive disorder, with the study currently not yet r…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families [NA]
Duke University is conducting a family-based intervention (SER Familia) to address syndemic conditions—including substance use, intimate par…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Prevention of Alzheimer's Disease With CR Plus tDCS in Mild Cognitive Impairment and Depression (PACt-MD) [NA]
The PACt-MD clinical trial investigates whether CR Plus transcranial direct current stimulation can help prevent Alzheimer's disease in indi…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Youth Emotional and Behavioral Treatment Study [NA]
Clinical trial update for a youth emotional and behavioral treatment study sponsored by Florida State University. The study investigates dep…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Anesthesia-Masked Psilocybin Therapy for Major Depression [Phase 2]
Stanford University's Phase 2 trial of anesthesia-masked psilocybin therapy for major depressive disorder is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Study Evaluating Safety and Efficacy of Ropanicant in MDD Patients [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of Ropanicant in adults with Major Depressive Disorder has completed.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe Depression [Phase 2, Phase 3]
A phase 2/3 clinical trial is evaluating the effectiveness and safety of JS1-1-01 Tablet for moderate-to-severe depression; the study is not…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Digital Intervention for the Modification of Lifestyles (iGame) [NA]
The University of Malaga–sponsored iGame digital lifestyle modification trial has completed. It investigates a digital intervention applicab…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: An Evaluation of the Impact of Pharmacist Comprehensive Medication Management With Pharmacogenomic Results to Improve Depression Outcomes in Community Pharmacies. [NA]
This clinical trial update investigates whether pharmacist comprehensive medication management guided by pharmacogenomic results can improve…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Identifying and Treating Depression in the Orthopaedic Trauma Population [Phase 4]
Phase 4 clinical trial investigating identification and treatment of depression in patients with orthopaedic trauma; currently recruiting. S…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3) [Phase 3]
A Phase 3 randomized study investigating azetukalner versus placebo for major depressive disorder is currently recruiting (X-NOVA3).
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: The Brain-Heart-Gut Connection [NA]
The update notes the completion of a clinical trial studying the brain-heart-gut connection in patients with major depressive disorder and f…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Treating Immuno-metabolic Depression With Anti-inflammatory Drugs [Phase 3]
This clinical trial update describes a Phase 3 study evaluating anti-inflammatory drugs for immuno-metabolic depression, with the trial curr…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study to Assess the Safety and Effectiveness of NMRA-335140-501 [Phase 3]
This clinical trial update describes a Phase 3 study (NMRA-335140-501) evaluating safety and effectiveness in Major Depressive Disorder, whi…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder [Phase 3]
This document provides a status update for a Phase 3 trial evaluating the oral NMRA-335140 in major depressive disorder, noting the study is…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Deaf CBT-TS to Reduce Suicide Risk [NA]
Update on a clinical trial evaluating Deaf CBT-TS for reducing suicide risk. The study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
NIMH-sponsored clinical trial evaluating mood and anxiety disorders, including bipolar disorder and major depressive disorder, is currently …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder [Phase 3]
Phase 3 clinical trial update evaluating oral NMRA-335140 versus placebo in adults with Major Depressive Disorder; study status shows as act…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of Ropanicant in patients with Major Depressive Disorder has completed.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Stress, Inflammation and Neuroimaging in Major Depressive Disorder as Compared to Premenstrual Dysphoric Disorder
A recruiting study comparing stress, inflammation, and neuroimaging features in individuals with major depressive disorder versus premenstru…