Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression [NA]
An update on a clinical trial testing home-based cognitive rehabilitation plus transcranial direct current stimulation to improve cognition …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder [Phase 3]
This clinical trial update describes a Phase 3 study evaluating the efficacy and safety of esketamine for reducing symptoms of major depress…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Cancer Related Major Depression Treated With a Single Dose of Psilocybin [Phase 2]
A Phase 2 clinical trial is evaluating a single dose of psilocybin for cancer-related major depressive disorder, with recruitment ongoing.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)
This ClinicalTrials.gov study is recruiting to evaluate sleep EEG features in adults with major depressive disorder, sponsored by Janssen Re…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Can the Affects Conveyed by Baroque Music Reduce Anxiety in Patients With Major Depressive Disorder ? [NA]
A clinical trial tested whether listening to Baroque music can reduce anxiety in people with major depressive disorder. The study is complet…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ganoderma Spores Modulate the Gut-Brain Axis [NA]
A not-yet-recruiting clinical trial is evaluating Ganoderma spores as a potential modulator of the gut-brain axis in depression and thyroid …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Predictors and Clinical Outcomes of Patients With Coronary Heart Disease Co-morbid Depression Post Percutaneous Coronary Intervention
Clinical trial update evaluating predictors and clinical outcomes in patients with coronary heart disease and co-morbid depression after per…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Evaluation of the Bounce Back Program [NA]
The Bounce Back Program trial for depression (NCT01324648) has been terminated.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder [Phase 2]
A Phase 2 clinical trial assessing the efficacy of JNJ-89495120 for Major depressive disorder; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Adaptive Messaging to Support Depression Self-Management [NA]
A completed Northwestern University clinical trial evaluated adaptive messaging to support self-management of depression.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: CAMH PARTNERs Integrated Care Study [NA]
The CAMH PARTNERs Integrated Care Study is currently active but not recruiting. It investigates integrated care approaches for depression, a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of a Collaborative Behavioral Health Program Implementation in Primary Care
Clinical trial update describing the evaluation of a collaborative behavioral health program implemented in primary care to address depressi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Racial Disparities in Antidepressant Treatment After a Psychiatric Consultation
This clinical trial update describes ongoing research into racial disparities in antidepressant treatment after psychiatric consultation.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of an Online ACT and Compassion-based Intervention for Disorders of Gut-Brain Interaction [NA]
A clinical trial is evaluating an online Acceptance and Commitment Therapy (ACT) and compassion-based intervention for disorders of gut-brai…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Voice Activated Personal Assistant for Depression Among Older Adults [NA]
This ClinicalTrials.gov entry describes an active-but-not-recruiting study evaluating a voice-activated personal assistant for depression in…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth [NA]
A study evaluating behavioral telehealth in low-resource primary care settings for anxiety and depression in youth is currently enrolling by…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Combining Data Sources to Identify Effect Moderation for Personalized Mental Health
Johns Hopkins Bloomberg School of Public Health completed a study on combining data sources to identify effect moderation for personalized m…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Community-based Approach to Lowering Stress Through Mindfulness [NA]
Northwestern University is recruiting participants for a community-based mindfulness program aimed at lowering stress, with potential releva…
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FDA approval · 2026-04-09FDA Approved: DULOXETINE HYDROCHLORIDE — Supplemental Application (Alembic Pharmaceuticals Limited)
FDA approves a supplemental application for duloxetine hydrochloride as a generic product from Alembic Pharmaceuticals Limited.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Perioperative Mental Health in Orthopedic Surgery [NA]
This clinical trial evaluating perioperative mental health in older adults undergoing orthopedic surgery has completed and posted results.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures [NA]
This clinical trial evaluated behavioral activation and medication optimization for depression and anxiety in older adults undergoing cardia…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS) [NA]
Pilot clinical trial evaluating personalized aperiodic transcranial alternating current stimulation for antenatal depression, currently recr…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: IBDminds - Mapping the Influence of aNxiety and DepreSsion on IBD
This clinical trial update indicates the IBDminds study, which investigates how anxiety and depression influence inflammatory bowel disease,…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: The Role of Bioelements in Fibromyalgia: Disease Activity or Depression-Anxiety?
A completed clinical trial investigating the role of Bioelements in fibromyalgia and its association with anxiety and depression.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
A clinical trial update describes retrospective analyses of the Greenbrook Database evaluating mental health treatments, sponsored by Neuron…