Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Identifying and Measuring Depression in Older Cancer Patients
This clinical trial studies methods to identify and measure depressive symptoms in older adults with cancer. The study is currently active b…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use [NA]
A clinical trial evaluating remotely delivered programs to address COVID-19-related stress, depression, and substance use has completed.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Painhunting Therapy for Interpersonal Loss-Related Depression [NA]
A clinical trial evaluating Painhunting Therapy for depression related to interpersonal loss; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis [NA]
Pilot study evaluating sensor-informed smartphone-based mental health interventions to improve mood in individuals with early psychosis; not…
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CLINICAL_TRIALS withdrawal · 2026-04-07Clinical Trial Update: Non-Inferiority RCT Comparing Online and On-Site CBT in MDDi [NA]
A non-inferiority randomized trial comparing online versus on-site cognitive-behavioral therapy for Major Depressive Disorder has been withd…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Brief Trial of ACT-i for Adults With Chronic Insomnia [NA]
This clinical trial update indicates that ACT-i for adults with chronic insomnia is currently recruiting. The study also lists co-occurring …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Solomiya App - CBT-based Self-help Intervention [NA]
This update describes the Solomiya CBT-based self-help app for the prevention of sleep disorders, PTSD, and depression, which is not yet rec…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Mindfulness Engaged Neurostimulation for Depression (MEND II) [Phase 2]
Phase 2 clinical trial evaluating Mindfulness Engaged Neurostimulation for Depression is not yet recruiting, studying treatment options for …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Low Voltage Electrical Stimulation for Depression in Parkinson's Patients [NA]
This clinical trial update reports that a study investigating low voltage electrical stimulation to treat depressive symptoms in Parkinson's…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Home tDCS for the Treatment of Major Depression. [NA]
A trial is evaluating home-based transcranial direct current stimulation for major depressive disorder. The study is currently not recruitin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Behavioral and Neuronal Correlates of Human Mood States [NA]
A Stanford University clinical trial investigating behavioral and neuronal correlates of mood states in adults with Major Depressive Disorde…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This clinical trial update notes that enrollment is ongoing for an intra-ovarian Muse cell injection (Muse cell therapy) aimed at alleviatin…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS [NA]
A University of Minnesota-led study is recruiting to evaluate vagal excitation and its anatomical connections in epilepsy and major depressi…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Implementing Depression and Adherence Treatment [NA]
A University of Miami-sponsored clinical trial aims to implement treatments for depression and medication adherence in people living with HI…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Psilocybin-Assisted Therapy in Treatment-Resistant Depression [Phase 3]
Phase 3 trial evaluating psilocybin-assisted therapy for treatment-resistant depression is currently recruiting at the University of North C…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Shortened LSD Intervention for Major Depressive Disorder [Phase 1]
A Phase 1 clinical trial update describes a shortened LSD intervention for major depressive disorder. The study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation (rTMS) and P50 Evoked Potential Component [Phase 2]
This Phase 2 trial evaluating repetitive transcranial magnetic stimulation (rTMS) and the P50 evoked potential component in depression and s…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents [NA]
Colorado State University completed a mindfulness-based intervention trial in adolescents addressing depression and insulin resistance, with…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: CARED : A Novel Rapid Treatment Paradigm for Depression [NA]
This clinical trial update outlines CARED, a novel rapid treatment paradigm for major depressive disorder, with the study listed as not yet …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Trial [NA]
This document describes a protocol for an adaptive, internet-delivered, transdiagnostic intervention for emotional disorders that personaliz…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Mindfulness Training During Accelerated TMS for Depression [NA]
A clinical trial evaluating mindfulness training during accelerated transcranial magnetic stimulation for depression is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Antidepressant Response of DMT Masked With Propofol [NA]
A clinical trial is investigating antidepressant responses when DMT is masked with Propofol. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Brief, High-dose rTMS for Depression [NA]
Clinical trial update notes an active-not-recruiting study evaluating high-dose repetitive transcranial magnetic stimulation for depression,…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Transcranial Magnetic Stimulation for MCI [NA]
A clinical trial evaluating transcranial magnetic stimulation for mild cognitive impairment and depression is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Efficacy of Spectrally Optimized Light on Cognitive Impairment in Major Depressive Disorder and Its Neuroimaging Mechanisms [NA]
This ClinicalTrials.gov entry describes a study evaluating whether spectrally optimized light can improve cognitive impairment in major depr…