Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Mood And Kids diEt (MAKE-It) Pilot Trial [NA]
Pilot trial MAKE-It (Mood And Kids diEt) is investigating mood and diet interventions in adolescents with major depressive disorder and is c…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Holistic Integration for Healthy Longevity and Aging in Place [NA]
A clinical trial update from National Taiwan University Hospital describes a holistic aging-in-place program targeting cognitive decline, sa…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: EFCT vs. BCT for Depression and Anxiety in Married Couples [NA]
A clinical trial update indicates Beykoz University is actively recruiting for a study comparing EFCT and BCT to treat depression and anxiet…
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FDA approval · 2025-03-24FDA Approved: SPRAVATO — Supplemental Application (Janssen Pharmaceuticals Inc.)
FDA approved Janssen's supplemental application for SPRAVATO (esketamine hydrochloride) under NDA 211243, updating the product's indications…
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FDA approval · 2025-03-24FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
FDA approved a supplemental application for Bupropion Hydrochloride (generic) from Amneal Pharmaceuticals of New York LLC.
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: OSU6162 as add-on in SSRI/SNRI-resistant Depression [Phase 2]
A Phase 2 clinical trial evaluating OSU6162 as an add-on therapy for SSRI/SNRI-resistant depression; it is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: A Scalable Psychological Intervention for Earthquake Survivors in Türkiye [NA]
A completed clinical trial evaluating a scalable psychological intervention for earthquake survivors in Türkiye, focusing on reducing psycho…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Use of a Digitally Enabled App With Clinical Team Interface in the Management of Depression [NA]
This clinical trial update reports results from a completed study evaluating a digitally enabled app with a clinical team interface for mana…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Efficacy and Safety of tACS for Depression: a Multicenter RCT Study [NA]
A multicenter randomized controlled trial is evaluating the efficacy and safety of transcranial alternating current stimulation (tACS) for d…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: FMRI-neurofeedback in Depression [NA]
A clinical trial update shows ongoing recruitment for an fMRI-based neurofeedback study in unipolar depression at Maastricht University Medi…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Feasibility of SOLAR Group Program Among MHPSS Workers After the Earthquake [NA]
Koç University reports a feasibility study of the SOLAR Group Program for mental health and psychosocial support workers after the earthquak…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: SAINT for MDD in an Inpatient Setting Follow-on [Phase 2, Phase 3]
A Phase 2/3 clinical trial of the SAINT approach for major depressive disorder in an inpatient setting has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition [Phase 2, Phase 3]
Phase 2 and Phase 3 trials of the SAINT Neuromodulation System for Major depressive disorder have been terminated, including consideration o…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Cancer Caregiver Burden: Targeting Emotion Regulation in a Trial [NA]
Completed clinical trial from the University of Aarhus evaluating an emotion-regulation intervention to reduce caregiver burden in cancer ca…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Effects of Tuijing Therapy on Heart Rate Variability and Psychological Symptoms [NA]
Recruitment is ongoing for a study evaluating Tuijing Therapy's effects on heart rate variability and depressive symptoms. The trial is spon…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: The BIomarker Guided (BIG) Study for Depression [Phase 4]
Phase 4 biomarker-guided study in major depressive disorder has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Group Therapy for Women Prisoners With Comorbid Substance Use and Depression [NA]
Completed clinical trial evaluating group therapy for women prisoners with co-occurring substance use disorders and depression.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Near Infrared Spectroscopy (NIRS) for Assessment of Depression [NA]
This clinical trial is evaluating the use of Near Infrared Spectroscopy to assess depression in individuals with Major Depressive Disorder. …
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Mechanisms of Change in Psychotherapy [NA]
Clinical trial update indicating completion of a study on mechanisms of change in psychotherapy for depression, sponsored by Oslo University…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Treating Common Mental Disorders in Women in Mozambique by Addressing Intimate Partner Violence in Couples [NA]
This clinical trial in Mozambique aims to treat common mental disorders in women by addressing intimate partner violence in couples; the stu…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder [Phase 3]
Clinical trial update reports completion of a Phase 3 study evaluating lumateperone as monotherapy in bipolar depression and major depressiv…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Evaluation of a Training Course for Educational Professionals [NA]
A completed trial evaluating a training course for educational professionals aimed at addressing depression in children and adolescents.
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Behavioral Activation for Depression: A Randomized Controlled Trial [NA]
A randomized controlled trial evaluating Behavioral Activation for Depression conducted by the University of Aarhus; the study is currently …
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Frontline Clinician Psilocybin Study [Phase 3]
Phase 3 trial evaluating psilocybin for burnout in frontline clinicians has completed, with results posted in 2025. The study also explored …
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women [NA]
A completed clinical trial evaluated a healthy lifestyle intervention for high-risk minority pregnant women; results have been posted.