Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Evaluating an Online Acceptance and Commitment Training Program for Individuals with Chronic Health Conditions [NA]
Completed clinical trial evaluating an online acceptance and commitment training program for adults with chronic health conditions, aiming t…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Suubi-Mhealth: A Mobile Health Intervention to Address Depression Among Youth [NA]
Recruiting study of Suubi-Mhealth, a mobile health intervention to address depression among youth living with HIV infection.
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Combining Antidepressants and Attention Bias Modification in Depression [NA]
A clinical trial in depressive disorder evaluating the combination of antidepressants with attention bias modification, currently recruiting…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Evaluation of a Male-specific Psychotherapeutic Program for Major Depressive Disorders [NA]
An ongoing clinical trial is evaluating a male-specific psychotherapeutic program for adults with major depressive disorder and is currently…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Targeted ACT Compared to Supportive Therapy for Depression RCT [NA]
A completed randomized trial comparing Targeted Acceptance and Commitment Therapy to supportive therapy for depression.
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Treating Depression With Text Messaging [NA]
A completed clinical trial from the University of Tennessee evaluated treating moderate depression with a text messaging intervention.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation [NA]
Clinical trial evaluating the integration of behavioral approaches with vagus nerve stimulation for Major Depressive Disorder has completed …
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: PERsonalized Mood Augmentation Trial for Depressed Mood [NA]
This clinical trial update indicates that the PERsonalized Mood Augmentation Trial for depressed mood has completed.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Dose-Response Effect Exercise and Depression [NA]
This clinical trial update reports a completed study evaluating the dose-response effect of exercise on depression, sponsored by the Univers…
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CLINICAL_TRIALS other · 2025-03-27Clinical Trial Update: ACT for Mental Health in Neurological Disorders [NA]
Clinical trial update for ACT (Acceptance and Commitment Therapy) targeting mental health in neurological disorders shows the study is curre…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Tai Chi Versus Conventional Exercise to Alleviate Depression in Insomniacs [NA]
A completed clinical trial evaluating Tai Chi versus conventional exercise for reducing depressive symptoms in adults with chronic insomnia.
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Pharmacologic Treatment Augmentation in Chronic Depression [Phase 2]
A Phase 2 clinical trial evaluating pharmacologic augmentation strategies for chronic depression, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Adherence to Antidepressants During Pregnancy
A completed clinical trial evaluated adherence to antidepressant treatment among pregnant women. The study was conducted by Assistance Publi…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Effectiveness of an Ecological Momentary Emotion Regulation Intervention [NA]
A Heidelberg University–sponsored clinical trial is evaluating an ecological momentary emotion regulation intervention for major depressive …
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CLINICAL_TRIALS other · 2025-03-27Clinical Trial Update: METRIKAMIND - Development of a Digital Mental Health Ecosystem for Workplace Environments
Clinical trial update for METRIKAMIND exploring a digital mental health ecosystem for workplaces; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD) [Phase 1]
This document reports a Phase 1 pharmacokinetics and safety study of zuranolone in adolescent participants with major depressive disorder.
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Aerobic Versus Leisure Group for Adolescents With Depression [NA]
A clinical trial is evaluating aerobic exercise versus a leisure activity control in adolescents with major depressive disorder and is curre…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Collaborative Stepped-Care and Productive Ageing Program for Older People With Depressive Symptoms [NA]
Completed clinical trial evaluating a collaborative stepped-care and productive ageing program for older people with depressive symptoms.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Multicenter Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder [Phase 3]
A Phase 3 multicenter trial evaluating lumateperone as adjunctive therapy for adults with major depressive disorder has completed and result…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Depressive State After Sleeve Gastrectomy
This ClinicalTrials.gov entry reports a completed study investigating depressive states following sleeve gastrectomy in individuals with mor…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi [NA]
A recruiting clinical trial in Malawi is evaluating enhanced problem-solving therapy plus HIV engagement support to improve perinatal mental…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk [NA]
This clinical trial update concerns a psychophysiological study of pain perception in patients with major depressive disorder and suicidal r…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: A Randomized Control Trial of Enhanced Cognitive Behavioural Group Therapy for Older Adults with Depression: Efficacy Across Older Age-Groups [NA]
A randomized control trial evaluating enhanced cognitive behavioural group therapy for older adults with major depressive disorder, assessin…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Cognitive Function and EEG Brain Network Remodeling Among Users of Hearing Aids With ARHL
This clinical trial update describes an ongoing study evaluating cognitive function and EEG brain network remodeling in older adults with ag…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Effect of Psychedelic VR-augmented Therapy on Patients With Clinical Depression [NA]
A clinical trial is evaluating psychedelic VR-augmented therapy for depression, with recruitment currently ongoing and no results yet.