Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
Clinical trial update announcing the CDRIN Maritimes Registry, a prospective registry for depression and trauma-related disorders, currently…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: IM Ketamine vs Midazolam for Suicidal ER Patients [Phase 4]
A Phase 4 randomized trial comparing intramuscular ketamine to midazolam for emergency department patients with depression and suicidal idea…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use [NA]
A clinical trial evaluating whether genetic counselling can prevent mental health problems associated with cannabis use; the study is curren…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Decision Making Tool for Firearm Storage [NA]
This clinical trial update reports on a completed study evaluating a decision-making tool for firearm storage intended for individuals with …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Accelerated iTBS for Depression: Monitoring Brain Hemodynamics With Simultaneous iTBS/fNIRS [NA]
A clinical trial evaluating accelerated intermittent theta-burst stimulation (iTBS) for depression with concurrent fNIRS-based monitoring of…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Treatment Interrupts Depression Early [Phase 2]
A Phase 2 trial evaluating treatment interruption for depression is currently recruiting in Nova Scotia.
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: DBS for Depression [NA]
A Baylor College of Medicine study is recruiting participants for a deep brain stimulation trial to treat major depressive disorder. The ent…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Psilocybin Therapy for Depression in Parkinson's Disease [Phase 2]
Phase 2 clinical trial evaluating psilocybin therapy for depression in Parkinson's disease is currently recruiting. The study investigates p…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Effects of Schema Therapy vs. Cognitive Behavioral Therapy vs. Individual Supportive Therapy [NA]
A completed clinical trial compared schema therapy, cognitive behavioral therapy, and individual supportive therapy for major depressive dis…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: NQ TMS for MDD Therapy Using 1 Day x 3 Sessions Protocol for Adult Patient [NA]
A completed clinical trial update for NQ TMS therapy in adults with Major Depressive Disorder using a 1-day, 3-session protocol.
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients [NA]
Clinical trial update on an adjuvant accelerated piTBS approach to reduce suicidal ideation in patients with treatment-resistant major depre…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast Cancer [Phase 3]
A Phase 3 feasibility trial of Tele-IPT and tele-pharmacotherapy for patients with Major Depressive Disorder and non-metastatic breast cance…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Taiwan Post-Stroke Disability Study
Taiwan-based post-stroke disability study led by National Taiwan University Hospital is currently recruiting participants.
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Affect Treatment for Depression and Anxiety (TAD Pilot) [NA]
The TAD Pilot trial (NCT06488859) investigating affect treatment for depression and anxiety has completed.
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans [NA]
A randomized trial comparing yoga with coherent breathing versus walking in U.S. veterans with major depressive disorder and post-traumatic …
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community [NA]
This completed clinical trial evaluated a Screening, Brief Intervention, and Referral to Treatment (SBIRT) program for opioid-dependent pris…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD [NA]
This clinical trial update shows ongoing recruitment for a study to reduce suicide risk and depressive symptoms among aging caregivers of pe…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: GW117 ODT (Orally Disintegrating Tablets) Safety and Pharmacokinetics Study in Healthy Subjects [Phase 1]
Phase 1 safety and pharmacokinetics study of GW117 orally disintegrating tablets conducted in healthy subjects; Major depressive disorder is…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Preconception and Pregnancy Obesity Treatment and Prevention Among Women With a History of Depression [NA]
A clinical trial evaluating preconception and pregnancy obesity treatment and prevention in women with a history of depression has completed…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Scaling Well-Being for Educators During COVID-19 [NA]
A completed clinical trial from the University of Wisconsin, Madison investigated scaling well-being interventions for educators during COVI…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression
A clinical trial update from Max-Planck-Institute of Psychiatry describes deep phenotyping to infer treatment response in treatment-resistan…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets [Phase 2]
A completed Phase 2 study that uses high-field neuroimaging to map the neural circuits linked to irritability in people with major depressiv…
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FDA approval · 2025-05-08FDA Approved: MIRTAZAPINE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for mirtazapine by Aurobindo Pharma Limited under ANDA077376.
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT [Phase 4]
Phase 4 clinical trial evaluating esketamine/propofol anesthesia versus methohexital anesthesia for electroconvulsive therapy in depression;…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Cross-Cultural Differences in the Network Structure of Social Anxiety and Body Dysmorphic Symptoms
A completed clinical trial update examining cross-cultural differences in the network structure of social anxiety and body dysmorphic sympto…