Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Resettled Refugee Families for Healing [NA]
The study 'Resettled Refugee Families for Healing' led by Washington University School of Medicine is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease [NA]
Completed clinical trial from the University of North Carolina investigated central neurophysiologic correlates of non-motor symptoms in Par…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Prevention of Psychological Health Problems Via Integrated Operational Support [NA]
New York University is recruiting for a clinical trial testing an integrated operational support approach to prevent psychological health pr…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Targeting IL-17A for Treatment-Resistant Depression [Phase 2]
Phase 2 trial investigating an IL-17A-targeting therapy for treatment-resistant depression has completed and posted results.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence [NA]
This document is a study protocol for a culturally adapted psychological support program aimed at reducing depression, anxiety, PTSD symptom…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: A Feasibility Study of Nature-based Health Interventions for People With Mild to Moderate Anxiety, Depression and Stress [NA]
A feasibility study is evaluating nature-based health interventions for adults with mild to moderate anxiety, depression, and stress, and is…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Cortical/Subcortical Circuits in Late-Life Depression
A completed clinical trial examining cortical and subcortical brain circuits in late-life depression.
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Augmenting Single-session Behavioral Activation (BA) With Delta-beta Transcranial Alternating Current Stimulation (tACS) for the Treatment of Depression [NA]
A completed clinical trial evaluated adding delta-beta transcranial alternating current stimulation (tACS) to single-session Behavioral Acti…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Myelin, Glia and Depression in Type 2 Diabetes
A completed clinical trial examining the roles of myelin and glial cells in depression among people with type 2 diabetes.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Accelerated iTBS for Depression and Suicidality [NA]
A clinical trial update shows Accelerated intermittent theta-burst stimulation for Major Depressive Disorder with suicidality is not yet rec…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
This clinical trial update describes a study led by Douglas Mental Health University Institute examining behavioural development, long-term …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Pain Reduction Through Empowered Recovery (PRIME) Study [NA]
The PRIME clinical trial, led by Johns Hopkins University, focuses on pain reduction and depressive symptoms and is currently active but not…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: DIALOG: Understanding Disorganisation: A Language-focused Global Initiative in Psychosis
This entry describes the DIALOG study, a language-focused global initiative in psychosis led by Douglas Mental Health University Institute. …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder [EARLY_Phase 1]
A Phase 1 clinical trial is recruiting to evaluate xenon inhalation therapy for major depressive disorder and bipolar disorder.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT [NA]
An ongoing randomized trial in Greece is evaluating trauma-focused cognitive behavioral therapy for post-traumatic stress disorder and relat…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling [NA]
A Stanford University-sponsored trial investigates ketogenic metabolic therapy (ketogenic dieting) for schizophrenia, bipolar disorder, and …
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Salivary Oxytocin as a Biomarker in Psychedelic Assisted Psychotherapy
A completed clinical trial evaluating salivary oxytocin as a biomarker in psychedelic-assisted psychotherapy for depression and anxiety.
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FDA approval · 2025-05-15FDA Approved: SPRAVATO — Supplemental Application (Janssen Pharmaceuticals Inc.)
The FDA approved a supplemental application for Spravato (esketamine hydrochloride) submitted by Janssen Pharmaceuticals. The action updates…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study [NA]
A feasibility study investigating patient- and family-centered care in the adult intensive care unit, sponsored by Herlev Hospital; the tria…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: SKY Breath Intervention
A UCSF-sponsored study of the SKY Breath Intervention is currently active but not recruiting, evaluating its effects on depression and anxie…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder [Phase 2]
Phase 2 clinical trial update comparing psilocybin with pimavanserin versus psilocybin alone for major depressive disorder; recruitment is o…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Skills for Wellness [NA]
This is a clinical trial update for the Skills for Wellness study. It is currently recruiting participants with schizophrenia, bipolar disor…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Exercise to Augment TMS in Those With Treatment Resistant Depression [NA]
A clinical trial update describes a study evaluating exercise as an adjunct to transcranial magnetic stimulation for treatment-resistant dep…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Personalized Indications for CBT and Antidepressants in Treating Depression [Phase 4]
This clinical trial update outlines a Phase 4 study exploring personalized indications for cognitive behavioral therapy (CBT) and antidepres…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Depression and Anxiety Among Chronic Pain Patients in the Netherlands
A clinical trial conducted at Amsterdam UMC (VUmc) evaluating chronic pain with comorbid depression and anxiety has completed.