Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Heart-Smile Training Intensive Introduction Program [NA]
A completed clinical trial update for a depression-focused training program called Heart-Smile Training Intensive Introduction Program, spon…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Long Term Follow Up KET-PD
An ongoing Yale-sponsored long-term follow-up study (KET-PD) for Parkinson's disease, including depressive symptoms, is currently enrolling …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Predictors of Cognitive Outcomes in Geriatric Depression [Phase 4]
Phase 4 clinical trial update examining predictors of cognitive outcomes in older adults with major depressive disorder; the study is curren…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit [NA]
Completed clinical trial evaluating procedures for a study of the AYA Survivors Coping and Emotional Needs Toolkit. The trial addressed depr…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents [NA]
A clinical trial is recruiting to evaluate a digital mood-enhanced CBT-I program designed to improve depressive symptoms in adolescents with…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: 6 Weeks Right-Amygdala TIS for Depression [NA]
A clinical trial update indicates a study of right-amygdala TIS therapy for major depressive disorder is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Caregiver Stress and Sleep Study [NA]
A University of Pittsburgh–led clinical trial is recruiting to study caregiver stress and sleep, assessing depressive symptoms and caregiver…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder [NA]
Clinical trial update reporting on the efficacy of a dextromethorphan-bupropion combination compared with selective serotonin reuptake inhib…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Music Interventions for Dementia and Depression in Elderly Care [NA]
A completed clinical trial evaluating music interventions for dementia and depression in elderly care settings. The sponsor is NORCE Norwegi…
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FDA approval · 2025-07-08FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for quetiapine fumarate from Aurobindo Pharma Limited to market the generic product for the same ind…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Real-life Assessment of Brexpiprazole (Rexulti) in Schizophrenia and in Depressive Disorders
This clinical trial update reports a real-world assessment of brexpiprazole (Rexulti) for schizophrenia and depressive disorders, currently …
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression [NA]
This update covers StratCare Trial 2, which is evaluating the clinical and cost-effectiveness of AI-driven stratified care for depression. T…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Effectiveness of a Guided Mental Health Chatbot for Youth Living in Lithuania [NA]
A clinical trial in Lithuania is evaluating the effectiveness of a guided mental health chatbot for youth with symptoms of depression and an…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Mental Health Assessment and Prescribing by Alberta Pharmacists [NA]
A completed University of Alberta study investigates mental health assessment and prescribing practices by Alberta pharmacists for major dep…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Intern Health Study 2025 [NA]
The University of Michigan's Intern Health Study 2025 is currently enrolling by invitation, focusing on Major Depressive Disorder and relate…
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FDA approval · 2025-07-03FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for Bupropion Hydrochloride XL, adding an extended-release formulation of bupro…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Study on the Intervention of Mindfulness-integrated Volleyball Course [NA]
A completed clinical trial assessing the effects of a mindfulness-integrated volleyball course on individuals with depression and anxiety.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Mood Effects of Serotonin Agonists: Depression [EARLY_Phase 1]
A Phase 1 study from the University of Chicago assessing mood-related effects of the serotonin agonist LSD in individuals with Major Depress…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Feasibility of Empowerment Group Therapy on Ukrainian Adult Outpatients [NA]
Feasibility study evaluating empowerment group therapy for depression in Ukrainian adult outpatients; currently recruiting.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Neural Circuit Effects of Ketamine in Depression [Phase 4]
A Phase 4 clinical trial studying the neural circuit effects of ketamine in major depressive disorder is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Optimizing Suicide Prevention Strategies for Pediatric Primary Care [NA]
A pediatric primary care trial is recruiting to optimize suicide prevention strategies for youth, focusing on suicidal ideation, self-injuri…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: The Medication Experience Study [NA]
The Medication Experience Study sponsored by Wake Forest University has completed, examining patients with hypertension, hyperlipidemia, dia…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Effect of Music Activities on Depression and Sleep Quality in Frail Older Adults [NA]
This clinical trial update reports a study assessing whether music activities can impact depression and sleep quality in frail older adults;…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Clinical Effect and Mechanism Study of Five Elements Music Therapy(FEMT) on Depression Disorder [NA]
A clinical trial evaluating the clinical effect and mechanism of Five Elements Music Therapy on depression.
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CLINICAL_TRIALS other · 2025-07-03Clinical Trial Update: Building Regulations in Dual Generations at KIDTHINK [NA]
ClinicalTrials.gov entry showing that a University of Manitoba study at KIDTHINK exploring depression, child development, and self-regulatio…