Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression [Phase 2]
Phase 2 trial evaluating an adaptive algorithm-based approach for treating adolescent depression has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Lipopolysaccharide (LPS) Challenge in Depression [Phase 1]
A Phase 1 study evaluating a lipopolysaccharide challenge in individuals with Major Depressive Disorder has completed, and results have been…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder [NA]
A Yale-sponsored clinical trial is evaluating transcranial magnetic stimulation as a treatment for depression in individuals with autism spe…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: An Evaluation of the Effect of Vitamin D Supplementation on Depressive Symptoms Among Chinese Early Adolescents [NA]
This clinical trial from Anhui Medical University evaluated whether Vitamin D3 (Cholecalciferol) supplementation can affect depressive sympt…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Family Support Intervention in Intensive Care Units [NA]
A completed clinical trial evaluating a family support intervention in intensive care units to improve outcomes for post-ICU survivors and t…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: EEG-Triggered rTMS and Group Therapy for Adolescents With Depression and Self-Harm [NA]
A completed clinical trial evaluating EEG-triggered repetitive transcranial magnetic stimulation (rTMS) in combination with group therapy fo…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Individualized Exploration of Aerobic Exercise-assisted Treatment of Depression [NA]
A clinical trial sponsored by Peking University is recruiting to evaluate aerobic exercise-assisted treatment for major depressive disorder.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Acute Psychological Sleep Stabilisation for Patients Hospitalised With Depression [NA]
Karolinska Institutet is conducting a clinical trial to evaluate acute psychological sleep stabilization for hospitalized patients with depr…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Assessment of an App-based Anxiety/Depression Program in a Population With Elevated Anxiety/Depression [NA]
A completed clinical trial assessed an app-based program for individuals with elevated anxiety and depression.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Association Between Sleep Disorders, Neck Pain, and Depression
A university-sponsored clinical trial is recruiting to study the associations between sleep disorders, neck pain, and depression in the cont…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Neuromodulation in Patients With Neuropathic Pain and Depression. [NA]
A clinical trial investigating neuromodulation for neuropathic pain and depression is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Intern Health Study
Clinical trial update indicates a depression study led by the University of Michigan is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder [Phase 3]
Phase 3 clinical trial evaluating lumateperone as adjunctive therapy for major depressive disorder is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Development and Evaluation of a Digital Aftercare Program for Adolescents (12-17 Years) With Depressive Symptoms After Hospital Discharge (Mind-WIN Pilot Study) (Mind-WIN Pilot) [NA]
This clinical trial update describes Mind-WIN Pilot, a digital aftercare program for adolescents (12-17) with depressive symptoms after hosp…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Depression and Pain Perseverance Through Empowered Recovery Intervention [NA]
A Johns Hopkins–sponsored trial of the Depression and Pain Perseverance Through Empowered Recovery Intervention has completed with results p…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Depression Trial) [NA]
This clinical trial update reports completion of a depression and opioid pragmatic trial in pharmacogenetics sponsored by Duke University, w…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Unified Protocol for Transdiagnostic Treatment for Depression and Anxiety in Adults [NA]
A completed clinical trial (NCT06002087) investigates a Unified Protocol transdiagnostic treatment for depression and anxiety in adults.
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity [NA]
A clinical trials update on digitally implementing the German S3 guideline for multimorbidity across several conditions, currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Vulnerability Markers for Depression
A completed clinical trial from The Hong Kong Polytechnic University examining vulnerability markers for depression, focusing on major depre…
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FDA approval · 2025-06-27FDA Approved: AMITRIPTYLINE HYDROCHLORIDE — Supplemental Application (AiPing Pharmaceutical, Inc.)
FDA approved AiPing Pharmaceutical, Inc.'s supplemental application for Amitriptyline Hydrochloride, resulting in changes to the approved pr…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Treatment Outcomes and Predictive Factors of the Effectiveness and Adherence of Moodpep: an Online Self-help Intervention for College Students With Depressive Symptoms [NA]
Completed clinical trial update of Moodpep, an online self-help intervention for depressive symptoms in college students, focusing on treatm…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression [Phase 1]
This update reports the completion of a Phase 1 study evaluating the acceptability and feasibility of a family-based prevention program to r…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans [Phase 1]
A Phase 1 trial evaluating repeated ketamine infusions for veterans with co-occurring Post-Traumatic Stress Disorder and Major Depressive Di…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Ketamine Associated ACC GABA and Glutamate Change and Depression Remission: [EARLY_Phase 1]
This early-phase trial reports ketamine-associated changes in ACC GABA and glutamate and notes depression remission. The study targets major…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Long-term Efficacy of Pramipexole in Anhedonic Depression [Phase 3]
A Phase 3 clinical trial evaluating the long-term efficacy of pramipexole in anhedonic depression is currently recruiting.