Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Teach Back Method on Depression Levels in Hemodialysis Patients [NA]
Completed clinical trial evaluating the Teach Back Method on depression levels in adults undergoing hemodialysis.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Sleep/Wake Cycle and Depression: An Imaging and Treatment Study [NA]
A clinical trial studying the sleep/wake cycle in depression using imaging and treatment approaches has completed. Sponsored by Stony Brook …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Evaluation Study of Medical-Social Collaboration Model for Middle-aged and Older Adults With Depressive Symptoms [NA]
An evaluation study by The University of Hong Kong is examining a medical-social collaboration model for depressive symptoms in middle-aged …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Benefits of Exergames on Neurocognitive Functions in Adults Suffering From Depression [NA]
MAP Institute is sponsoring a clinical trial to evaluate whether exergames improve neurocognitive function in adults with depression; the st…
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CLINICAL_TRIALS other · 2025-07-17Clinical Trial Update: Repetitive Versus Deep Transcranial Magnetic Stimulation for Major Depression [NA]
A clinical trial update indicates a study comparing repetitive transcranial magnetic stimulation versus deep transcranial magnetic stimulati…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain [NA]
This is an update on an ongoing clinical trial evaluating Just-In-Time Adaptive Interventions (JITAIs) in a digital mental health program fo…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Impact of Musical Therapeutic Intervention on Depression in Dementia Patients and Caregiver Burden [NA]
A completed clinical trial assessing the impact of musical therapy on depression in dementia patients and caregiver burden.
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Resilience and Satir Model Training for Adolescent Depression [NA]
This is a completed clinical trial assessing resilience and Satir model-based training for depression in adolescents. It lists The First Hos…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Evaluating a Personalised Online Program With Human Support for Women With Depression and Its Impact on Mental Health and Biological Changes [NA]
A clinical trial evaluating a personalised online program with human support for women with depression and its impact on mental health and b…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Somatic Symptoms and Depression in Undergraduate Physiotherapy Students: A Community-Based Cross-Sectional Study
A completed cross-sectional study from Cairo University examined somatic symptoms and depression among undergraduate physiotherapy students …
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses [NA]
RAND-sponsored clinical trial addressing opioid use disorder and related conditions has completed. The study focuses on improving addiction …
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression [Phase 2]
This clinical trial update describes a Phase 2 study comparing Ketamine-Assisted Psychotherapy (KAP) to ketamine alone for Major Depressive …
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FDA approval · 2025-07-15FDA Approved: ESCITALOPRAM OXALATE — Original Application (Ascent Pharmaceuticals, Inc)
FDA approved escitalopram oxalate as a generic product for Ascent Pharmaceuticals, Inc (ANDA 215177). It is intended to be used for the same…
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating roflumilast as an adjunct to antidepressants in adults with major depressive disorder has been w…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking [NA]
This clinical trial is recruiting to test combining repetitive transcranial magnetic stimulation (rTMS) with aerobic exercise to treat depre…
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: The Phosphodiesterase 5 Inhibitor Sildenafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients [NA]
The study evaluating sildenafil as an adjunct to antidepressants for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating vildagliptin as an adjunctive treatment for major depressive disorder was withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: The Phosphodiesterase Inhibitor Tadalafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients [Phase 1, Phase 2]
A Phase 1/2 trial evaluating tadalafil as an adjunct to antidepressants for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention [NA]
A completed Yale University clinical trial evaluated whether adding cognitive behavioral therapy after esketamine treatment can prevent rela…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Multicentre Clinical Study
A multicenter clinical study sponsored by Zhongda Hospital on objective diagnosis of depression; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Impact of Exercise Groups on Patient Mental Health and Wellbeing in an Acute Psychiatric Inpatient Unit [NA]
Johns Hopkins University reports an ongoing enrollment-by-invitation study evaluating the impact of structured exercise groups on mental hea…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Change My Story Task Shifted Mental Health Intervention [NA]
This clinical trial update notes a task-shifted mental health intervention called 'Change My Story' for people with HIV and depression, and …
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Computerized Depression Intervention in Veterans [NA]
A VA-sponsored clinical trial is testing a computerized depression intervention in veterans and is currently recruiting.
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FDA approval · 2025-07-11FDA Approved: FLUOXETINE — Supplemental Application (QUALLENT PHARMACEUTICALS HEALTH LLC)
FDA approved a supplemental application for fluoxetine hydrochloride submitted by Quallent Pharmaceuticals Health LLC, indicating an update …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents [NA]
A University of Alabama at Birmingham study is evaluating neural-derived plasma exosomal microRNAs as biomarkers for suicidality and treatme…