Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
A clinical trial update investigating genetic factors that influence SSRI-induced behavioral activation in patients with major depressive di…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Youth to Text or Telehealth for Engagement in HIV Care [NA]
A completed clinical trial evaluating whether text-based or telehealth interventions improve engagement in HIV care among youth, including p…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: SMART Trial to Predict Anhedonia Response to Antidepressant Treatment [Phase 4]
Phase 4 SMART trial to predict anhedonia response to antidepressant treatment in Major Depressive Disorder has completed.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use [Phase 1]
Phase 1 clinical trial evaluating a generative AI chatbot to help with anxiety and depression in people with cannabis use disorder; currentl…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV [NA]
Trial update on a remotely delivered Tai Chi/Qigong program to address depressive symptoms in older adults living with HIV. The study is cur…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Esketamine vs ECT for Acute Suicidality [NA]
A completed clinical trial comparing esketamine with electroconvulsive therapy for acute suicidality in mood disorders has finished.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression [Phase 4]
A Phase 4 trial evaluated low-dose ketamine infusions in adolescents with treatment-resistant depression and major depressive disorder. The …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Effect of Aerobic Exercise on Biomarkers in Depression [NA]
A clinical trial is evaluating the effect of aerobic exercise on biomarkers in individuals with major depressive disorder and the study is c…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: PRISM Neurofeedback Training for MDD Anhedonic Patients [NA]
The clinical trial evaluating PRISM neurofeedback training for patients with major depressive disorder and anhedonia has completed; sponsor …
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Adaptation and Evaluation of the KEEP Model [NA]
The KEEP Model study has completed its adaptation and evaluation for depression, anxiety, and post-traumatic stress disorder.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Precision Care for Major Depressive Disorder [Phase 4]
A Phase 4 clinical trial focused on precision care for major depressive disorder is currently enrolling by invitation. The study is sponsore…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: JoyPop Mobile Mental Health App With Indigenous Transitional-Aged Youth [NA]
Clinical trial update for JoyPop, a mobile mental health app for Indigenous transitional-aged youth; recruitment is ongoing to study its imp…
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FDA approval · 2025-09-04FDA Approved: SELEGILINE HYDROCHLORIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental application for Selegiline Hydrochloride from Chartwell RX, LLC, enabling the generic product's approval.
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients [Phase 3]
Phase 3 clinical trial comparing esketamine nasal spray with aripiprazole for treatment-resistant major depressive disorder in elderly patie…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Depression and Facial Identity Recognition Abilities in Patients With Multiple Sclerosis
This completed clinical trial studied depression and facial identity recognition abilities in patients with multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children [NA]
The trial evaluates the feasibility of a culturally adapted emotional-behavioral prevention program for American Indian children, focusing o…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life Depression [Phase 2]
Phase 2 clinical trial update evaluating clemastine to improve white matter integrity and antidepressant response in late-life depression; c…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-Life Depression
University of Illinois at Chicago is conducting a trial examining recurrence markers, cognitive burden, and neurobiological homeostasis in l…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury [NA]
This clinical trial is testing a scalable model of care to improve access to mental health services for patients after traumatic injury. It …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)
The UnMASCK study aims to unobtrusively monitor affective symptoms and cognition using keyboard dynamics, and the trial is currently active …
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
A clinical trial is evaluating artificial intelligence models to detect Autism Spectrum Disorder, Major Depressive Disorder and other mental…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Electroencephalographic Study of the Mechanisms of Inhibition of Emotional Memories in Young Healthy Subjects [NA]
A completed EEG study investigating neural mechanisms of inhibiting emotional memories in young healthy subjects, with related conditions in…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients [Phase 3]
This is a Phase 3 clinical trial comparing ketamine plus venlafaxine to placebo with venlafaxine in adults with a major depressive episode, …
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Digital Phenotypes for Predicting Depression
Clinical trial update describing a study that uses digital phenotypes to predict depression, sponsored by Korea University Anam Hospital. Th…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Group Drumming for Improving the Health of Community-Dwelling Elderly [NA]
A clinical trial update for a group drumming program aimed at improving health outcomes in community-dwelling elderly, with measures includi…