Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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FDA approval · 2025-09-12FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA granted a supplemental approval for a generic quetiapine fumarate product from Hikma Pharmaceuticals USA Inc. (ANDA 090749). The approva…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain [NA]
A completed clinical trial evaluated transcranial direct current stimulation for veterans with chronic pain, including co-occurring PTSD and…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Demonstration Study of the Effect of the Transcranial Direct Current Stimulation (tDCS) on Depressed Patients [NA]
Completed clinical trial from Yonsei University evaluating transcranial direct current stimulation for depression; results were posted on 20…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Smart Light Therapy Glasses for Sleep and Mental Wellness [NA]
A completed clinical trial from the University of Waterloo evaluated smart light therapy glasses for improving depressive symptoms and sleep…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Project neuroARTEMIS [NA]
A clinical trial called Project neuroARTEMIS (NCT06814275), sponsored by Wake Forest University Health Sciences, is currently recruiting to …
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Trajectories of Anxiety and Depression in Cancer Patients, Risk and Predictive Factors and Supportive Care; Prognostic Awareness and Shared Decision Making.
This clinical trial evaluates trajectories of anxiety and depression in cancer patients, including risk factors, prognostic awareness, and s…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Predicting Illness Trajectories In Fully Remitted Major Depression Using Concurrent TBS/fNIRS [NA]
This clinical trial investigates predicting illness trajectories in individuals with major depressive disorder who are in remission, using c…
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EMA approval · 2025-09-10EMA Authorised: Spravato (esketamine hydrochloride) — Janssen-Cilag International NV
The EMA authorised Spravato (esketamine hydrochloride) for depressive disorders, with Janssen-Cilag International NV as the marketing author…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Measurement of Serum Inflammatory Markers in Patients Treatment-resistant Depression Given Psilocybin
A clinical trial update from King's College London evaluating changes in serum inflammatory markers in adults with treatment-resistant major…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: JoyPop Mobile Mental Health App With Youth [NA]
This entry reports that the JoyPop mobile mental health app trial in youth is currently recruiting. The study targets emotion regulation and…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: JoyPop Mobile Mental Health App With Transitional-Aged Youth [NA]
The JoyPop mobile mental health app trial for transitional-aged youth is currently recruiting to study effects on emotion regulation, depres…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive Disorder [NA]
Clinical trial evaluating the efficacy and safety of low-dose laser acupuncture for insomnia associated with major depressive disorder; curr…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations [NA]
A Massachusetts General Hospital clinical trial is evaluating transcranial direct current stimulation (tDCS) to enhance executive function a…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: JoyPop Mobile Mental Health App With Post-Secondary Students [NA]
A completed clinical trial evaluating the JoyPop mobile mental health app for post-secondary students focusing on emotion regulation and dep…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression [NA]
An update on a clinical trial comparing accelerated vs. standard fMRI-guided intermittent theta-burst stimulation for treating adolescents w…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Accelerated TMS for Perinatal Depression [NA]
This Clinical Trials entry reports an ongoing study testing accelerated transcranial magnetic stimulation for perinatal and postpartum depre…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Effectiveness and Cost Effectiveness of OkeyMind for Social Anxiety Among Youth [NA]
A clinical trial update indicates that OkeyMind is being studied for effectiveness and cost-effectiveness in treating social anxiety among y…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth [NA]
A Vanderbilt University-sponsored clinical trial is comparing CBT enhanced with social cognitive training versus CBT alone in depressed yout…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network [NA]
A clinical trial is studying the neural mechanisms of intermittent theta burst stimulation in the core depression network for major depressi…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Valuation in Depressed Mood, Anhedonia, and Anxiety [NA]
ClinicalTrials.gov entry notes that Virginia Tech is recruiting for a study on neurobehavioral components of reward and loss valuation relev…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Phase 2b Study of ALTO-100 in MDD [Phase 2]
Alto Neuroscience's Phase 2b trial of ALTO-100 for Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Neurofeedback to Treat Depression [NA]
A completed clinical trial evaluating neurofeedback as a treatment for major depressive disorder.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: A Study on Functional Connectome and rTMS Intervention of Cognitive Flexibility Impairment in Patients With Major Depressive Disorder [NA]
This clinical trial update describes a study evaluating functional connectome metrics and rTMS for cognitive flexibility impairment in major…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Assessment of Daily Stressors in Children With Depressive Symptoms for the Development of a Gamified Emotion Regulation App
A clinical trial led by Ludwig-Maximilians-Universität München is evaluating the relationship between daily stressors and depressive symptom…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Psilocybin-Assisted Therapy for Intergenerational Trauma [Phase 2]
A Phase 2 clinical trial evaluating psilocybin-assisted therapy for intergenerational trauma is currently recruiting, assessing effects on p…