Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Decoding and Modulating Affective Brain States [NA]
Clinical trial from the University of Pennsylvania aims to decode and modulate affective brain states in people with major depressive disord…
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FDA approval · 2025-09-02FDA Approved: VENLAFAXINE HYDROCHLORIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved Sun Pharmaceutical Industries, Inc.'s supplemental application for a generic venlafaxine hydrochloride product.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Effect of Psilocybin Only and Psilocybin Assisted Cognitive Behavioral Therapy in the Management of Major Depressive Disorder and Associated Metabolic, Immune, Inflammatory, Neuroplasticity and Electrical Activity Markers [Phase 2]
Phase 2 clinical trial evaluating psilocybin alone and psilocybin-assisted cognitive behavioral therapy for major depressive disorder; the s…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN) [Phase 4]
Phase 4 clinical trial updates beta-arrestins’ relationship with venlafaxine response in adults with major depressive disorder. The study (D…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST) [NA]
A Northwestern University trial is recruiting to evaluate strategies for regulating emotions to prevent secondary trauma in professionals ex…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: The Impact of Coach-guided Risk Communication on the Risk of Major Depression [NA]
Dalhousie University is sponsoring a clinical trial to evaluate whether coach-guided risk communication can reduce the risk of major depress…
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CLINICAL_TRIALS other · 2025-09-02Clinical Trial Update: RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
RECOVERS is a clinical trial sponsored by the Medical University of South Carolina that is currently recruiting to evaluate realigning emoti…
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FDA approval · 2025-08-29FDA Approved: ESCITALOPRAM — Original Application (Almatica Pharma LLC)
FDA approved the original application for escitalopram from Almatica Pharma LLC, making a generic escitalopram available. The approval cover…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Treatment of Depression and/or Anxiety - the Tree Theme Method® (TTM) as an Intervention [NA]
The trial evaluating the Tree Theme Method as an intervention for depression and/or anxiety has completed; no results are provided in the sn…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault [NA]
This clinical trial update covers RESILIENT, a self-managed online platform for victims of sexual assault, studying its use in individuals w…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Virtual Reality-Augmented At-Home tDCS for Major Depression [NA]
This clinical trial update indicates that a study of VR-augmented at-home transcranial direct current stimulation for major depressive disor…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Early Psychological Intervention After Rape [NA]
This clinical trial evaluates an early psychological intervention after rape, with recruitment currently ongoing.
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine [Phase 2]
Phase 2 trial evaluating intravenous ketamine for reducing suicide risk in adolescents was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Efficacy of Metacognitive Training in Older Adults With Depression [NA]
Clinical trial investigating the efficacy of metacognitive training in older adults with depression has completed.
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD) [NA]
This clinical trial update reports on the feasibility of home-based intermittent 60Hz light therapy as a treatment for major depressive diso…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Geolocation Positional System (GPS) Experience [NA]
A University of Miami study on a Geolocation Positional System (GPS) Experience is currently recruiting. It lists emotions, anhedonia, and d…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Mobile Screening for Major Depressive Disorder in Adults From an Ethnically and Socioeconomically Diverse Population. [NA]
An ongoing Erasmus Medical Center study is evaluating mobile screening for Major Depressive Disorder in ethnically and socioeconomically div…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: rTMS for Youth Inpatients With Depression [NA]
A clinical trial update shows a study evaluating repetitive transcranial magnetic stimulation (rTMS) for youths inpatients with major depres…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Students [NA]
A Cairo University clinical trial will study how gender differences and exercise intensity affect depression and anxiety symptoms in univers…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Berries, Bugs, and the Blues [NA]
This entry reports the completion of a clinical trial assessing depressive symptoms, with results posted on 2025-08-22.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age [NA]
The University of Aarhus completed a clinical trial evaluating Cognitive Behavioural Therapy for complicated grief reactions in older adults…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder [NA]
This clinical trial update indicates that a study assessing intradermal acupuncture guided by acupoint biology for major depressive disorder…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Relevance of a Telemedicine Monitoring in the Management of Depression [NA]
A clinical trial in Paris is studying telemedicine monitoring as a management tool for Major Depressive Disorder and is currently recruiting…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode [Phase 3]
Phase 3 clinical trial investigating adding buprenorphine at analgesic doses to treat severe suicidal ideation during a major depressive epi…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Optimizing Care for Cancer Survivors With Depression: Project 3 [NA]
Clinical trial 'Optimizing Care for Cancer Survivors With Depression: Project 3' is currently recruiting at the Medical University of South …