Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Creating a Global Research Database That Connects Genetic Information and Long-term Health Data to Improve Personalized Treatment for People With Serious Mental Illness
This update describes an initiative to create a global research database that links genetic information with long-term health data to improv…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Engaging Traditional Birth Attendants to Reduce Maternal Depression in Rural Kenya [NA]
This is a completed clinical trial in rural Kenya evaluating whether engaging traditional birth attendants can reduce maternal depression. T…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Enhanced Brief CBT for Suicidal Inpatients With Mood Disorders [NA]
A clinical trial update describing an enhanced brief cognitive behavioral therapy program for suicidal inpatients with mood disorders; the s…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Mental Health Mission Mood Disorder Cohort Study
Clinical trial update from the University of Oxford for a mood disorder cohort study. The trial is currently not recruiting and covers major…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Effect of Theta-burst rTMS Therapy on the Clinical and Cognitive Symptoms of Patients With Therapy Resistant Depression and Response Prediction With Neuroimaging Methods. [NA]
An ongoing study evaluating theta-burst repetitive transcranial magnetic stimulation (rTMS) for therapy-resistant major depressive disorder,…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Effectiveness of CAT-GSH for Returning Patients [NA]
Clinical trial update on the effectiveness of CAT-GSH for patients with anxiety and depression; the study is currently recruiting.
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FDA approval · 2025-10-02FDA Approved: MIRTAZAPINE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved a generic form of mirtazapine (Camber Pharmaceuticals) via Original Application.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Semaglutide for the Treatment of Cognitive Dysfunction in Major Depressive Disorder [Phase 2]
A Phase 2 clinical trial evaluating semaglutide for cognitive dysfunction in adults with major depressive disorder has completed.
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment
This clinical trial update describes a retrospective observational study on intensity effects in psychedelic-assisted treatment for several …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline [NA]
The University of Delaware study on daily stress and vascular function in midlife explored whether stress-related vascular changes predict c…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Effects of Exercıse on Chronotype, Sleep Qualıty and Depressıon Symptom Level in Unıversıty Students [NA]
A university-based clinical trial is evaluating whether exercise influences chronotype, sleep quality and depressive/anxiety symptoms in stu…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression [Phase 4]
A Phase 4 clinical trial at Stanford University is evaluating propofol-enhanced assessment of ketamine for chronic pain and depression; the …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study [NA]
A clinical trial compares Mindfulness-based Cognitive Therapy with the Health Enhancement Program for managing chronic pain and depression a…
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FDA approval · 2025-10-01FDA Approved: BUPROPION HYDROCHLORIDE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' original-application for generic bupropion hydrochloride, authorizing a new generic entry of the antide…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families [NA]
This clinical trial update describes a hybrid Type 1 randomized pilot evaluating a peer-led family and social strengthening group interventi…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Behavioural Activation Therapy and Esketamine for Resistant Depression [NA]
A clinical trial evaluating behavioural activation therapy in combination with esketamine for treatment-resistant depression and related moo…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Evaluating the Big Five Intervention in Norway [NA]
This clinical trial update shows the Big Five Intervention trial in Norway is currently recruiting for participants with anxiety and depress…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: The Counselor Led Resident Wellness Study [NA]
A counselor-led resident wellness study sponsored by the University of Nevada, Reno, evaluating a wellness-program intervention for burnout,…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Death Anxiety, Depression and Anxiety: An Experimental Study [NA]
A recruiting clinical trial from Babes-Bolyai University investigating death anxiety, depression, and anxiety in an experimental study.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Prevention of ICU-Related Anxiety in Lung Transplantation by Virtual Reality Therapy - PIRAT Study [NA]
A completed clinical trial (PIRAT) evaluated virtual reality therapy to prevent ICU-related anxiety in patients undergoing lung transplantat…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms [NA]
The VA Office of Research and Development is sponsoring a clinical trial evaluating a self-help intervention for post-9/11 veterans with dep…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Link Between Reduction of Suicide Ideation by Esketamine in Add-On and Initial Levels of Psychological Pain and Anhedonia
A clinical trial update examines whether adding esketamine to ongoing treatment reduces suicidal ideation in major depressive disorder. It a…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems [NA]
Completed clinical trial evaluating the efficacy of a transdiagnostic sleep and circadian intervention for adults with depression, bipolar d…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Cognitive Behavioral and Faith Fellowship to Improve Thy Health [NA]
Clinical trial investigating cognitive behavioral therapy combined with faith fellowship to improve health in individuals with depression; c…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Engagement in CHildhood-Onset Systemic Lupus [NA]
A clinical trial at Montefiore Medical Center is enrolling by invitation for childhood-onset systemic lupus erythematosus, with depression a…