Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Using rTMS to Treat Depression
This entry notes an ongoing clinical trial at Florida International University evaluating repetitive transcranial magnetic stimulation (rTMS…
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EMA approval · 2025-10-15EMA Authorised: Duloxetine Viatris (previously Duloxetine Mylan) (duloxetine) — Viatris Limited
The European Medicines Agency authorised a duloxetine product marketed as Duloxetine Viatris by Viatris Limited for several indications incl…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis [NA]
A clinical trial update for a closed-loop mobile application designed to manage depression in people with multiple sclerosis; the study is a…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Psilocybin in Chronic Low Back Pain and Depression [Phase 1]
A Phase 1 clinical trial at Johns Hopkins is evaluating the safety and potential effects of psilocybin for chronic low back pain and depress…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Effect of Vagal Nerve Stimulation on Gastric Motor Functions [NA]
A Mayo Clinic study is currently recruiting to evaluate the effect of vagus nerve stimulation on gastric motor function in people with depre…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Audio-based Mental Health Intervention Study [NA]
Penn State University completed a clinical trial evaluating an audio-based intervention for depressive symptoms. The study status is listed …
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Our Voices Matter: Intervention for Depression in Youth [NA]
This clinical trial update notes a youth depression intervention is currently recruiting. It will evaluate depressive symptoms, allostatic l…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Cognitive Fitness for Depression in Older Adults [NA]
This clinical trial update indicates that the study titled 'Cognitive Fitness for Depression in Older Adults' has completed, assessing cogni…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Intravenous Ketamine for Treatment-Resistant Depression [Phase 2]
Phase 2 clinical trial evaluating intravenous ketamine for treatment-resistant depression is currently recruiting.
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FDA approval · 2025-10-09FDA Approved: SPRAVATO — Supplemental Application (Janssen Pharmaceuticals Inc.)
The FDA approved a supplemental application for SPRAVATO (esketamine hydrochloride) filed by Janssen Pharmaceuticals Inc.
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FDA approval · 2025-10-09FDA Approved: ESCITALOPRAM — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for Escitalopram oxalate (escitalopram) from Sun Pharmaceutical Industries, authorizing its marketin…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness [NA]
A clinical trial record describing a study on the acceptability and feasibility of a work-oriented social-cognitive skills training for vete…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change [NA]
This completed VA-sponsored trial evaluated a one-day life skills workshop for veterans with traumatic brain injury, chronic pain, and co-oc…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: PEERS Plus mHealth Enhanced Peer Support [NA]
The PEERS Plus mHealth Enhanced Peer Support trial for depression in older adults has completed, and results were posted on 2025-10-08.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Evaluation of Dalia Solution For Depressed Patient [NA]
This clinical trial update indicates a planned evaluation of Dalia Solution for depression, with the study currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Exercise Plus Duloxetine for Knee Osteoarthritis [Phase 2]
Phase 2 trial evaluating exercise plus duloxetine for knee osteoarthritis with comorbid depression; the study has completed.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients
Clinical trial update indicating that Zealand University Hospital is enrolling by invitation in a study using speech-based AI to detect deme…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment) [NA]
Clinical trial update for IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment) showing status as Recruiting…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Investigating Neural Response Variability as a Single-patient Predictor of Successful CBT in Clinical Psychiatry
Karolinska Institutet's clinical trial investigates whether neural response variability can serve as a single-patient predictor of successfu…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Disorder [NA]
This update describes a study validating a composite medical device that uses a blood biomarker-based algorithm and the MDQ to diagnose Bipo…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ) [Phase 2]
A Phase 2 randomized proof-of-concept study evaluating the efficacy of a psilocybin and trazodone combination for treatment-resistant depres…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Computerized Substance Use and Depression Screening and Behavioral Treatment in HIV Primary Care [NA]
This Clinical Trial Update notes that the study evaluating computerized substance-use and depression screening with a behavioral treatment i…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback [NA]
A University of Michigan-led clinical trial is recruiting to test real-time fMRI neurofeedback targeting large-scale brain networks in major…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors [Phase 2]
Phase 2 study evaluating Brief Behavioral Activation to treat depression in older adult cancer survivors. The trial is currently active but …
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FDA approval · 2025-10-06FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Micro Labs Limited)
FDA approved a supplemental application for Bupropion hydrochloride from Micro Labs Limited.