Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression [Phase 4]
Phase 4 clinical trial evaluating how ovarian hormone withdrawal influences anhedonia and reward sensitivity in women with premenstrual exac…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers [NA]
A completed clinical trial (MAC) evaluated an intervention to reduce anxiety in older adults with cancer and their caregivers. The study was…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression [NA]
A clinical trial is currently recruiting to test accelerated neuromodulation of the anterior cingulate cortex for major depressive disorder.
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults [NA]
Ongoing study evaluating Deep Transcranial Magnetic Stimulation (Deep TMS) for comorbid depression and cognitive impairment in older adults;…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression [NA]
The VA-sponsored trial assessed whether adding a tailored cognitive behavioral therapy mobile skills app can influence depression outcomes; …
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II [Phase 2]
A Phase 2 trial called SWIPED Stage II is testing whether propofol-induced slow-wave sleep can treat depression; the study is currently recr…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: Neighborhood-based Physical and Social Activity for Older Black Caregivers and People Living With Dementia [NA]
Completed clinical trial from Oregon Health and Science University evaluating neighborhood-based physical and social activity for older Blac…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: RESISTance Exercise for Depression Trial [NA]
Clinical trial update for the RESISTance Exercise for Depression trial investigating exercise as a treatment for Major Depressive Disorder. …
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Stress Dynamics and Familial Risk for Depression in Female Adolescents [NA]
This clinical trial update shows the study 'Stress Dynamics and Familial Risk for Depression in Female Adolescents' is currently recruiting …
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FDA approval · 2025-10-22FDA Approved: ARIPIPRAZOLE — Original Application (QUAGEN PHARMACEUTICALS LLC)
FDA approved the original application for aripiprazole from Quagen Pharmaceuticals LLC, marking the availability of a generic aripiprazole p…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: South Asians With Type 2 Diabetes at Risk for Depression [NA]
This clinical trial update notes a study examining depression risk among South Asian individuals with Type 2 diabetes. The trial is currentl…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics [NA]
A clinical trial is investigating digital therapeutics to target network dysfunction in apathy associated with late-life depression and is c…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Assessing an EEG Biomarker of Response to TMS for Major Depression
An ongoing clinical trial is evaluating an EEG biomarker to predict which patients with major depressive disorder respond to transcranial ma…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Training Reward Responsiveness Through Virtual Reality [Phase 2]
A Phase 2 clinical trial sponsored by the University of California, Los Angeles is evaluating training reward responsiveness using virtual r…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder [Phase 3]
A Phase 3 randomized trial compares Azetukalner to placebo in Major Depressive Disorder, with recruitment currently ongoing.
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Mindful Moms Randomized Control Trial [NA]
Mindful Moms is an ongoing randomized controlled trial at Virginia Commonwealth University. It tests a mindfulness-based intervention for de…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: Open-Label of SPN-820 in Adults With Major Depressive Disorder [Phase 2]
A Phase 2 open-label study of SPN-820 in adults with major depressive disorder has completed and posted results.
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
This clinical trial update describes research into the nociceptin/orphanin FQ receptor as a potential target for major depressive disorder a…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression [NA]
This completed clinical trial evaluated online interventions to increase help-seeking for anxiety and depression among sexual and gender min…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Mental Health CPR for Cancer Survivors [NA]
Recruitment is open for a clinical trial evaluating mental health CPR for cancer survivors, focusing on depression and anxiety disorders in …
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Assessment of Music Experiences in Navigating Depression [NA]
A clinical trial evaluating music-based experiences for navigating depression has completed. The study is sponsored by Icahn School of Medic…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Assessment of Music Experiences in Navigating Depression Part 2 [NA]
This clinical trial update indicates a recruiting study by Icahn School of Medicine at Mount Sinai exploring how music experiences can help …
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Cancer Within a Pandemic: A Telemental Health Intervention [NA]
A Wake Forest University Health Sciences trial evaluating a telemental health intervention for cancer patients during the pandemic was termi…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: fMRI Accelerated TMS Depression
An ongoing clinical trial at Medical University of South Carolina is evaluating accelerated, fMRI-guided transcranial magnetic stimulation f…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety [NA]
A Stanford-sponsored clinical trial investigated a novel sleep intervention aimed at modulating the emotion regulation brain network to trea…