Major Depressive Disorder
📧 Sign up to get email alerts when something new happens for Major Depressive Disorder.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty [NA]
A clinical trial update indicates RXWell is recruiting to test whether it can decrease post-operative opioid use in patients undergoing tota…
-
CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Electronic Media and Its Application in Psychotherapy [NA]
A clinical trial conducted by McLean Hospital evaluating electronic media in psychotherapy for anxiety disorders and depression has complete…
-
CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Comparing Behavior Therapy and Yoga for Treating Depression Among Adults [NA]
A clinical trial comparing behavior therapy and yoga as treatments for depression in adults; the study is currently active but not recruitin…
-
CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder [Phase 1]
Phase 1 clinical trial update for psilocybin in major depressive disorder; the Yale University study is currently active but not recruiting.
-
CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: TEAMS R34 #3: Team-Based Implementation Strategy for Pediatric Depression Screening [NA]
Update on the TEAMS R34 #3 trial evaluating a team-based implementation strategy for pediatric depression screening; the study is currently …
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Sleep TMS for Depression [NA]
A trial evaluating sleep-targeted transcranial magnetic stimulation for major depressive disorder has completed. No efficacy results are pro…
-
CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Neuromodulation for Comorbid Hoarding Disorder and Depression [NA]
Completed clinical trial evaluating neuromodulation as a treatment for hoarding disorder with comorbid depression.
-
CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)
ASPREE-XT is an extension study of the aspirin trial in older adults, with active but not recruiting status to continue evaluating aspirin's…
-
CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: An Open-label Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder [Phase 3]
Open-label Phase 3 trial evaluating lumateperone as adjunctive therapy for Major depressive disorder; results have been posted.
-
CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI) [NA]
The clinical trial update reports on the feasibility of the Individualized Positive Psychosocial Intervention (IPPI) for individuals with de…
-
CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial [NA]
A randomized controlled trial assessing an AI chatbot for postpartum education to aid recovery and reduce loneliness, with recruitment not y…
-
EMA approval · 2025-10-31EMA Authorised: Zurzuvae (zuranolone) — Biogen Netherlands B.V.
The EMA authorised Zurzuvae (zuranolone) by Biogen Netherlands B.V. for depression and postpartum depression.
-
CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Designing a Mobile App to Support Academic Success for Student Veterans [NA]
This completed study evaluated a mobile app to support academic success for student veterans. It reported results related to mental health c…
-
CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression [Phase 4]
Phase 4 clinical trial investigating the neural processes and circuitry underlying threat sensitivity as a treatment target for co-morbid an…
-
CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Pharmacologic Augmentation of TMS for Depression With D-serine [Phase 1]
A Phase 1 trial is assessing whether D-serine can augment transcranial magnetic stimulation for depression and it is currently recruiting.
-
CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2 [NA]
This document reports the completion of Study 2 evaluating hyperthermia as an adjunct treatment for major depressive disorder. Results have …
-
CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Message-Based Psychotherapy and Digital Treatment Sequences for Depression [NA]
A Talkspace-sponsored study evaluating message-based psychotherapy and digital treatment sequences for depressive disorder has completed, an…
-
CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety [Phase 2]
A Phase 2 mechanistic study to assess a single dose of CYB003 in participants with depression and anxiety, currently not recruiting.
-
CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of NBI-1070770 in Adults With Major Depressive Disorder [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of NBI-1070770 in adults with Major depressive disorder has completed.
-
CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) [Phase 3]
A Phase 3 clinical trial to evaluate the efficacy and safety of NBI-1065845 as adjunctive therapy for adults with Major Depressive Disorder …
-
CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: iCBT With TMS in Patients With MDD [NA]
This clinical trial update notes that a study of internet-based cognitive behavioral therapy combined with transcranial magnetic stimulation…
-
CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration [NA]
This ClinicalTrials.gov entry reports the completed results of the RISE program, a resilience intervention for men leaving incarceration, ev…
-
CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
A supplemental brain imaging study is investigating how cannabis use, neuroinflammation, and suicidal ideation relate to PTSD and depressive…
-
CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt [NA]
This update indicates WellPATH-PREVENT, a mobile intervention trial, is currently recruiting middle-aged and older adults hospitalized for s…
-
CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms [NA]
A clinical trial evaluating a mobile health intervention aimed at improving psychosocial functioning in veterans with post-traumatic stress …