Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: BIOMARKERS FOR DRUG SELECTION IN DEPRESSION
A clinical trial investigating biomarkers to guide drug selection for major depressive disorder has completed, sponsored by Neomente SAS.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorders [NA]
This clinical trial evaluates a mobile health intervention to improve medication adherence and reduce blood pressure in people with hyperten…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial [Phase 2]
This Phase 2 randomized, midazolam-controlled trial evaluates the combination of i-CBT and intravenous ketamine for suicidality in treatment…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Using Virtual Reality Technology on Depression, Anxiety, and Stress Among Palestinian Patients Undergoing Breast Biopsy [NA]
Clinical trial update about a study using virtual reality to address depression, anxiety, and stress in Palestinian patients undergoing brea…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT) [Phase 2]
This document provides an update on a Phase 2 trial evaluating D-Cycloserine augmentation of intermittent theta burst stimulation (iTBS) for…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: iTBS-Neurosplasticity for Female Youth With Depression [NA]
A clinical trial update for iTBS-based neuromodulation aiming to treat depressive disorder in female youth, currently not recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: A Qualitative Analysis of Youth Responses to Depression Education Delivered on Social Media
A completed qualitative study from Ludwig-Maximilians-Universität München examining how youth respond to depression education delivered via …
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: College Student Stress: Transitions Over Time [NA]
A completed clinical trial evaluating college student stress and depressive symptoms has posted results (NCT06583096).
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic
A completed clinical study evaluating post-traumatic stress, anxiety, depressive symptoms, and burnout among nursing home staff in Occitanie…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media [NA]
A clinical trial at Ludwig-Maximilians-Universität München evaluating a social media–based intervention to enhance depression literacy and r…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups
This clinical trial aims to subclass mental health conditions within diabetes using digital twins to enable precision mental health tracking…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Neurofeedback to Treat Depression - 2 [NA]
University of Pennsylvania-sponsored clinical trial evaluating neurofeedback as a treatment for major depressive disorder, currently recruit…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD) [NA]
This clinical trial update indicates ongoing recruitment for two studies evaluating Magnetic Seizure Therapy in bipolar depression and treat…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD) [Phase 2]
A Phase 2 clinical trial evaluating an SGLT2 inhibitor for major depressive disorder is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Validation of the French Translation of the Scale HSCL25 in the Diagnosis of Depression in Primary Care [NA]
This completed study validates the French translation of the Hopkins Symptoms Checklist-25 (HSCL-25) for screening and diagnosing depression…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: The Purpose of the Study is to Investigate if a Smartphone App Combined With Internet Based Cognitive Behavioural Therapy (ICBT) Leads to Improved Symtoms in Depressive Adults on Antidepressive Medicine, Compared to a Wait-list Control Condition [NA]
This clinical trial update describes a study designed to determine if a smartphone app combined with internet-based cognitive behavioral the…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: SMART-DAPPER: Leveraging the Depression And Primary-care Partnership for Effectiveness-implementation Research Project [NA]
The SMART-DAPPER study on depression and posttraumatic stress disorder in primary care has completed, with results posted on 2025-12-02.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Feasibility and Efficacy of rTMS in Depression in Patients With Autism Spectrum Disorder (ASD) [NA]
A clinical trial evaluating the feasibility and efficacy of repetitive transcranial magnetic stimulation for depression in individuals with …
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Healing Lodge First Face Training Evaluation Study [NA]
A completed evaluation of the Healing Lodge First Face Training program has posted results, assessing outcomes in individuals with addiction…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Assessment of the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Patients With Major Depressive Disorder [NA]
An ongoing clinical trial is evaluating the efficacy and safety of fecal microbiota transplantation for patients with major depressive disor…
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CLINICAL_TRIALS other · 2025-12-02Clinical Trial Update: INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco [NA]
The INNOV5-MH-MAROC trial aims to integrate mental health care for adolescents and adults in primary care centers and schools in Morocco. Th…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: A Phase II Study to Evaluate NH102 for Depression [Phase 2]
A Phase II study evaluating NH102 for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Tertulias Social Isolation Women's Groups Study [NA]
This is a completed clinical trial update from the University of New Mexico on a social isolation and depression study. The results have bee…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: EL-SHIN Therapy for Depressive Symptoms [NA]
EL-SHIN Therapy for depressive symptoms is currently recruiting in a Monash University Malaysia clinical trial for major depressive disorder…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
The VESPAR Project is a recruiting clinical trial from the University of Leicester investigating vascular mechanisms across stroke, dementia…