Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Pivotal U.S. Clinical Validation of AI-COA® for Depression and Anxiety
The document describes a pivotal U.S. clinical validation study for the AI-COA digital outcome assessment in depression and anxiety, with th…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: The Effects of Exercise and Music Combination on Drug Cravings, Depression and Self-Efficacy Among Drug Addicts [NA]
This completed clinical trial evaluated whether a combination of exercise and music could reduce drug cravings and depression and improve se…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Mechanism of Action of Transcranial Magnetic Stimulation [NA]
This clinical trial update describes the mechanism of action study of transcranial magnetic stimulation for major depressive disorder, with …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress [NA]
A clinical trial exploring how mindfulness-based interventions affect psychopathology and symptoms in people with depression, anxiety, and e…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Cognitive Remediation in Forensic Mental Health Care [NA]
This trial entry indicates that a cognitive remediation study for forensic mental health care is currently recruiting participants, examinin…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program [NA]
This clinical trial update reports that the SWAG-R program from Nova Southeastern University is currently recruiting to assess effects on an…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Brain Markers of Depression Vulnerability: the Case of Prefrontal Haemodynamic Response
The clinical trial investigating brain markers of depression vulnerability using prefrontal haemodynamic response has completed.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Aging and Reward System Response to Inflammation and Anxiety Study [Phase 1]
Phase 1 clinical trial from UCLA evaluating how aging and inflammation interact with anxiety to affect reward system response; the study has…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Study of Sleep Inertia in Major Depressive Disorder by the Psychomotor Vigilance Task
The document describes a recruiting clinical trial examining sleep inertia in individuals with major depressive disorder using the psychomot…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya [NA]
This Kenya-based clinical trial update describes a study sponsored by Florida International University testing mental health treatment to re…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.
This update covers an ongoing clinical trial investigating the mechanisms of synaptic degeneration and how these mechanisms relate to clinic…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Improving Treatment for Depression in General Practice Using a Step-by-Step Care Plan. [NA]
Aalborg University Hospital is recruiting a clinical trial to test a step-by-step care plan aimed at improving depression treatment in gener…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics [NA]
Recruitment is ongoing for a stepped-care intervention addressing perinatal mood and anxiety disorders in women attending maternal and child…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Brain Stimulation and Decision-making [NA]
Emory University is conducting a clinical trial to study brain stimulation and decision-making in depression, and participant recruitment is…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, or Bipolar Disorder Attending a Psychiatric Day Hospital in Taiwan [NA]
A completed clinical trial in Taiwan evaluated the effectiveness of Traditional Chinese Metacognitive Training for schizophrenia, major depr…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Sustained Mood Improvement With Laughing Gas Exposure [Phase 3]
A Phase 3 clinical trial sponsored by Women's College Hospital is investigating nitrous oxide exposure for sustained mood improvement in maj…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Research on Three-level Prevention and Intervention for Elderly Depression in Urban Community [NA]
A clinical trial evaluating a three-level prevention and intervention approach for depression in elderly urban residents has completed.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Mood Lifters for Undergraduates [NA]
A completed University of Michigan clinical trial studying mood-related interventions for undergraduates with depression and anxiety.
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS [NA]
A clinical trial update notes an active-not-recruiting study evaluating repetitive transcranial magnetic stimulation (rTMS) for acute depres…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Personalized Integrated Chronotherapy for Perinatal Depression [NA]
Rhode Island Hospital-sponsored trial investigating personalized integrated chronotherapy for perinatal depression has completed and posted …
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE) [NA]
Active, not recruiting clinical trial (INSPIRE) from Henry Ford Health System investigating insomnia and depression in expecting mothers. Th…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Multimodal Intervention for Older Adults After an Earthquake [NA]
A completed clinical trial evaluated a multimodal intervention for frailty, PTSD, depression, malnutrition, and falls in older adults after …
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Ketamine for the Treatment of Depression in Parkinson's Disease [Phase 2]
Phase 2 clinical trial of ketamine for depression in Parkinson's disease has completed.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Enoxolone in Major Depression - Biomarker-outcome Relationship [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial investigates enoxolone in major depressive disorder, focusing on biomarker–outcome relationships, and is cu…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: At-Home tDCS as Maintenance Therapy [NA]
The document reports a ClinicalTrials.gov study evaluating at-home transcranial direct current stimulation as maintenance therapy for major …