Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Neurophysiologic Predictors of Outcome With rTMS Treatment of Major Depressive Disorder [Phase 4]
Phase 4 trial update on repetitive transcranial magnetic stimulation for major depressive disorder, focusing on neurophysiologic predictors …
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Evaluation of States in Major Depressive Patients With Cancer, Hospitalized in a Hospital Palliative
A completed clinical trial evaluating states of major depressive symptoms in hospitalized cancer patients receiving palliative care.
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Trigeminal Nerve Stimulation for Depression: Dose Finding [Phase 2]
A Phase 2 dose-finding trial evaluating trigeminal nerve stimulation for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Adjunctive Transcranial Direct Current Stimulation for Cognition in Major Depression [Phase 4]
Phase 4 clinical trial assessing adjunctive transcranial direct current stimulation to improve cognition in adults with major depressive dis…
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Personalized Indicators for Predicting Response to SSRI Treatment in Major Depression (The PRISE-MD Study) [Phase 4]
Phase 4 study investigating personalized indicators to predict response to SSRI treatment in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication [Phase 4]
Phase 4 clinical trial update examining brain activity changes and treatment response in people with depression who are taking antidepressan…
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CLINICAL_TRIALS trial_result · 2013-02-04Clinical Trial Update: The Effect on Cognition of Terminating ECT Induced Seizures With Propofol [NA]
Completed clinical trial investigating the effect on cognition of terminating ECT-induced seizures with propofol in major depression.
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FDA approval · 2013-02-01FDA Approved: ZOLOFT — Supplemental Application (ROERIG)
FDA approved a supplemental application for ZOLOFT (sertraline hydrochloride) submitted by ROERIG.
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FDA label_change · 2013-02-01FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA supplemental approval for sertraline hydrochloride from Mylan to update labeling.
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FDA approval · 2013-01-29FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (Rising Pharma Holdings, Inc.)
FDA approved a supplemental application for sertraline hydrochloride from Rising Pharma Holdings, Inc., indicating approval of changes to th…
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury [Phase 1]
Phase 1 trial evaluating interpersonal psychotherapy for depressed adolescents engaging in non-suicidal self-injury; study completed with re…
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CLINICAL_TRIALS trial_result · 2013-01-25Clinical Trial Update: Comparison of Tianeptine Versus Escitalopram Patients Major Depressive Disorder [Phase 4]
A Phase 4 study comparing tianeptine with escitalopram in adults with major depressive disorder has completed, reporting results from the he…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Exercise to Treat Depression in Individuals With Coronary Heart Disease [Phase 3]
Phase 3 trial evaluating exercise as a treatment for depression in individuals with coronary artery disease has completed and posted results…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression [Phase 4]
Phase 4 trial updating paroxetine/bupropion in suicide attempters/ideators with major depression; study terminated with results posted in 20…
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CLINICAL_TRIALS research · 2013-01-23Clinical Trial Update: A Pilot Trial Of Transdiagnostic Cognitive Behavioural Therapy (tCBT) For Depression And Anxiety In Older People [NA]
A pilot trial of transdiagnostic cognitive behavioral therapy (tCBT) for depression and anxiety in older people.
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Cortical GABA Concentrations in Insomnia
A completed Yale University–sponsored trial examined cortical GABA concentrations in people with insomnia, with and without major depressive…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Quetiapine in Melancholic Depression [Phase 4]
Phase 4 clinical trial update evaluating quetiapine for melancholic depression has completed.
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Effectiveness of Deep Transcranial Magnetic Stimulation in Depression [Phase 2, Phase 3]
A completed Phase 2 and Phase 3 trial evaluated the effectiveness of deep transcranial magnetic stimulation for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Study of 6(S)-5-MTHF Among Selective Serotonin Reuptake Inhibitor-Resistant Outpatients With Major Depressive Disorder [Phase 4]
Phase 4 study evaluating 6(S)-5-MTHF (L-methylfolate) as an add-on in SSRI-resistant major depressive disorder; results from the trial were …
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CLINICAL_TRIALS trial_result · 2013-01-14Clinical Trial Update: Pilot Study of Open-label Placebo to Treat Major Depressive Disorder [Phase 2]
This update reports results from a Phase 2 open-label pilot study evaluating open-label placebo as a treatment for Major Depressive Disorder…
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CLINICAL_TRIALS trial_result · 2013-01-11Clinical Trial Update: Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS) [NA]
This update indicates the clinical trial examining cerebral function in patients with chronic hepatitis C infection has completed, assessing…
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FDA approval · 2013-01-10FDA Approved: VIIBRYD — Supplemental Application (Allergan, Inc.)
FDA approved Allergan's supplemental application for VIIBRYD (vilazodone hydrochloride), the antidepressant vilazodone.
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CLINICAL_TRIALS research · 2013-01-10Clinical Trial Update: Algorithm Guided Treatment Strategies for Major Depressive Disorder [Phase 4]
This document announces an ongoing Phase 4 clinical trial at Shanghai Mental Health Center evaluating algorithm-guided treatment strategies …
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Sedation and Psychopharmacology in Critical Care [NA]
The terminated clinical trial update reports a study sponsored by Virginia Commonwealth University evaluating sedation and psychopharmacolog…
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CLINICAL_TRIALS trial_result · 2013-01-08Clinical Trial Update: Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression [Phase 4]
Phase 4 trial evaluating whether quantitative EEG predictors can forecast response to psychotherapy versus antidepressant treatment in major…